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Fusion of COPII vesicle with Golgi complex
Stable Identifier
R-HSA-2213243
Type
Reaction [dissociation]
Species
Homo sapiens
Compartment
Golgi membrane
,
ER to Golgi transport vesicle membrane
,
endoplasmic reticulum membrane
ReviewStatus
5/5
Locations in the PathwayBrowser
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Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
MHC class II antigen presentation (Homo sapiens)
Fusion of COPII vesicle with Golgi complex (Homo sapiens)
General
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
The COPII vesicle uncoats and fuses with the cis-Golgi, releasing the MHC II:Ii complex into the Golgi.
Literature References
PubMed ID
Title
Journal
Year
11790530
Trafficking of MHC class II molecules in the late secretory pathway
Roche, PA
,
Hiltbold, EM
Curr Opin Immunol
2002
10480952
Direct transport of newly synthesized HLA-DR from the trans-Golgi network to major histocompatibility complex class II containing compartments (MIICS) demonstrated using a novel tyrosine-sulfated chimera
Davidson, HW
J Biol Chem
1999
Participants
Input
Nonameric complex in COPII vesicle [ER to Golgi transport vesicle membrane]
(Homo sapiens)
Output
COPII [endoplasmic reticulum membrane]
(Homo sapiens)
Nonameric complex [Golgi membrane]
(Homo sapiens)
Participates
as an event of
MHC class II antigen presentation (Homo sapiens)
Orthologous Events
Fusion of COPII vesicle with Golgi complex (Bos taurus)
Fusion of COPII vesicle with Golgi complex (Canis familiaris)
Fusion of COPII vesicle with Golgi complex (Danio rerio)
Fusion of COPII vesicle with Golgi complex (Mus musculus)
Fusion of COPII vesicle with Golgi complex (Rattus norvegicus)
Fusion of COPII vesicle with Golgi complex (Sus scrofa)
Authored
Garapati, P V (2012-02-21)
Reviewed
Neefjes, J (2012-05-14)
Created
Garapati, P V (2012-04-30)
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