Type XII and XIV collagens associate with type I and type II fibrils.

Stable Identifier
Reaction [omitted]
Homo sapiens
Locations in the PathwayBrowser
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Certain fibril-associated collagens with interrupted triple helices (FACITs) associate with the surface of collagen fibrils, where they may serve to limit fibril fusion and thereby regulate fibril diameter (Ansorge et al. 2009, Gordon & Hahn 2010). Type XII and XIV colalgens are found in association with type I (Walchli et al. 1994) and type II (Watt et al. 1992, Eyre 2002).

Literature References
PubMed ID Title Journal Year
1400327 Characterization of collagen types XII and XIV from fetal bovine cartilage

Watt, SL, Lunstrum, GP, McDonough, AM, Keene, DR, Burgeson, RE, Morris, NP

J Biol Chem 1992
8207089 Tissue-specific expression of the fibril-associated collagens XII and XIV

Wälchli, C, Koch, M, Chiquet, M, Odermatt, BF, Trueb, B

J Cell Sci 1994
Participant Of
Orthologous Events
Cite Us!