NOTCH2 stimulates transcription of HES5

Stable Identifier
R-HSA-2197564
Type
Reaction [BlackBoxEvent]
Species
Homo sapiens
Compartment
nucleoplasm
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NOTCH2 stimulates transcription of HES5
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NOTCH2 coactivator complex bound to HES5 promoter stimulates HES5 transcription (Shimizu et al. 2002).

Literature References
PubMed ID Title Journal Year
11866432 Functional diversity among Notch1, Notch2, and Notch3 receptors

Shimizu, K, Hirai, H, Kumano, K, Hamada, Y, Saito, T, Chiba, S

Biochem Biophys Res Commun 2002
Participants
Input
Output
Participates
as an event of
This event is regulated
Positively by
Regulator
NOTCH2 Coactivator Complex:HES5 gene [nucleoplasm] (Homo sapiens)
Active Unit
NOTCH2 Coactivator Complex [nucleoplasm]
Inferred From
Notch2 stimulates transcription of Hes5 (Mus musculus)
Authored
Orlic-Milacic, M  (2013-01-11)
Reviewed
Ilagan, MXG  (2013-04-25)
Boyle, S  (2013-04-25)
Created
Orlic-Milacic, M  (2012-04-12)
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