Reactome | USE1 [endoplasmic reticulum membrane]

USE1 [endoplasmic reticulum membrane]

Stable Identifier

R-HSA-2193119

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane

Synonyms

D12, Vesicle transport protein USE1, USE1_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9NZ43 USE1

Gene Names

USE1, USE1L, MDS032

Chain

chain:1-259

Reference Genes

BioGPS Gene:55850 USE1

COSMIC (genes):USE1 USE1

CTD Gene:55850 USE1

dbSNP Gene:55850 USE1

ENSEMBL:ENSG00000053501 USE1

ENSEMBL_homo_sapiens_GENE:ENSG00000053501.14 USE1

HGNC:30882 USE1

KEGG Gene (Homo sapiens):55850 USE1

Monarch:55850 USE1

NCBI Gene:55850 USE1

OMIM:610675 USE1

UCSC:Q9NZ43 USE1

Reference Transcript

Other Identifiers

11720705_a_at

16859437

219348_PM_at

219348_at

221706_PM_s_at

221706_s_at

3824104

3824106

3824108

3824109

3824110

3824111

3824112

3824113

3824114

3824115

3824116

3824117

54641_at

55850

8026679

A_14_P102357

A_14_P120146

A_23_P79122

A_24_P393303

A_33_P3392823

GE82382

GO:0005484

GO:0005515

GO:0005783

GO:0005789

GO:0006890

GO:0007041

GO:0015031

GO:0016020

GO:0016192

GO:0030137

GO:0030163

GO:0031201

GO:0031410

GO:0032940

GO:0043226

GO:0060090

GO:0061024

GO:0061025

HMNXSV003052270

ILMN_1664243

PH_hs_0001494

PH_hs_0037665

TC19000328.hg

g13543708_3p_s_at

g8923935_3p_at

Participates

as an output of

NSF ATPase activity dissociates cis-SNARE at the ER (Homo sapiens)

as a component of

STX18:USE1L:BNIP1 [endoplasmic reticulum membrane] (Homo sapiens)

Inferred To

Use1 [endoplasmic reticulum membrane] (Drosophila melanogaster)

Use1 [endoplasmic reticulum membrane] (Mus musculus)

Use1 [endoplasmic reticulum membrane] (Rattus norvegicus)

USE1 [endoplasmic reticulum membrane] (Bos taurus)

USE1 [endoplasmic reticulum membrane] (Caenorhabditis elegans)

USE1 [endoplasmic reticulum membrane] (Canis familiaris)

USE1 [endoplasmic reticulum membrane] (Dictyostelium discoideum)

USE1 [endoplasmic reticulum membrane] (Gallus gallus)

USE1 [endoplasmic reticulum membrane] (Saccharomyces cerevisiae)

USE1 [endoplasmic reticulum membrane] (Sus scrofa)

use1 [endoplasmic reticulum membrane] (Danio rerio)

use1 [endoplasmic reticulum membrane] (Schizosaccharomyces pombe)

use1 [endoplasmic reticulum membrane] (Xenopus tropicalis)

Cross References

RefSeq

NP_060937.1, XP_016882464.1

OpenTargets

ENSG00000053501

GeneCards

Q9NZ43

HPA

ENSG00000053501-USE1

Ensembl

ENSP00000473239, ENSP00000472362, ENSP00000263897, ENST00000595101, ENST00000263897, ENST00000596136, ENSG00000053501

PRO

Q9NZ43

Pharos - Targets

Q9NZ43

Interactors (32)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9P2W9 STX18	1	STX18 [endoplasmic reticulum membrane] (R-HSA-2029079)	0.81	11
UniProt:Q8WVM8 SCFD1	1	SCFD1 [cytosol] (R-HSA-5688147)	0.725	6
UniProt:Q12981 BNIP1	1	BNIP1 [endoplasmic reticulum membrane] (R-HSA-6810950)	0.725	6
UniProt:O43264 ZW10	1	ZW10 [cytosol] (R-HSA-377880)	0.723	8
UniProt:Q6NUQ1 RINT1	1	RINT1 [cytosol] (R-HSA-6810991)	0.723	9
UniProt:P54920 NAPA	1	NAPA [cytosol] (R-HSA-264469)	0.643	3
UniProt:A2RRP1 NBAS	1	NBAS [cytosol] (R-HSA-6810973)	0.643	12
UniProt:Q9NUG4 CCM2L			0.556	3
UniProt:Q6NSX1 CCD70			0.556	3
UniProt:Q12846 STX4	4	STX4 [phagocytic vesicle membrane] (R-HSA-2029044) STX4 [plasma membrane] (R-HSA-181519) STX4 [cytosol] (R-HSA-114505) p-STX4 [cytosol] (R-HSA-114681)	0.556	3
UniProt:Q16623 STX1A	5	STX1A [plasma membrane] (R-HSA-449128) STX1A(?-288) [plasma membrane] (R-HSA-5246518) STX1A(1-?) [cytosol] (R-HSA-3065964) STX1A [cytosol] (R-HSA-9609866) STX1A [endoplasmic reticulum membrane] (R-HSA-9609878)	0.556	3
UniProt:P14373 TRIM27	2	TRIM27 [nucleoplasm] (R-HSA-2997690) TRIM27 [cytosol] (R-HSA-8851002)	0.556	3
UniProt:Q15125 EBP	1	EBP [endoplasmic reticulum membrane] (R-HSA-195697)	0.556	3
UniProt:Q13520 AQP6	1	AQP6 [transport vesicle membrane] (R-HSA-431741)	0.556	3
UniProt:Q9BQE5 APOL2			0.556	3
UniProt:Q9BXU9 CABP8			0.556	3
UniProt:P50222 MEOX2			0.556	3
UniProt:Q8N5M9 JAGN1			0.556	3
UniProt:Q9NY72 SCN3B	1	SCN3B [plasma membrane] (R-HSA-197921)	0.556	3
UniProt:Q5SR56 MF14B			0.556	3
UniProt:Q8N661 TMEM86B	1	TMEM86B [endoplasmic reticulum membrane] (R-HSA-8874443)	0.556	3
UniProt:J3KQ12 J3KQ12			0.556	3
UniProt:O43889 CREB3	7	CREB3(1-256) [nucleoplasm] (R-HSA-8874190) CREB3(1-256) [cytosol] (R-HSA-8874135) CREB3(1-291) [Golgi membrane] (R-HSA-8874181) CREB3(257-291) [Golgi membrane] (R-HSA-8874207) CREB3 [Golgi membrane] (R-HSA-8874123) CREB3(292-371) [Golgi membrane] (R-HSA-8874173) CREB3 [endoplasmic reticulum membrane] (R-HSA-8874165)	0.553	2
UniProt:Q96G97 BSCL2			0.553	2
UniProt:O75396 SEC22B	6	SEC22B [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5688566) SEC22B [phagocytic vesicle membrane] (R-HSA-8863938) SEC22B [endoplasmic reticulum membrane] (R-HSA-5688150) SEC22B [ER to Golgi transport vesicle membrane] (R-HSA-5688565) SEC22B [transport vesicle] (R-HSA-6810994) SEC22B [Golgi membrane] (R-HSA-6810993)	0.527	3
UniProt:A2RUC4 TYW5	1	TYW5 [cytoplasm] (R-HSA-6783500)	0.527	2
UniProt:O95183 VAMP5			0.527	3
UniProt:Q9Y5E2 PCDB7			0.527	2
UniProt:Q8WU76 SCFD2			0.527	3
UniProt:O95249 GOSR1	2	GOSR1 [transport vesicle] (R-HSA-6784834) GOSR1 [Golgi membrane] (R-HSA-6807753)	0.527	2
UniProt:Q86Y82 STX12			0.527	2
UniProt:Q9UFG5 CS025			0.527	3

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