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3x4Hyp-3Hyp-GalHyl-COL18A1(24-1754) [extracellular region]
Stable Identifier
R-HSA-2192850
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
3x4Hyp-3Hyp-GalHyl-COL18A1, 3,4-Hyp 5-Gal-Hyl-collagen alpha-1(XVIII) chain, 3,4-hydroxyprolyl-collagen alpha-1(XVIII) chain, COL18A1, COIA1_HUMAN
Locations in the PathwayBrowser
Expand all
Extracellular matrix organization (Homo sapiens)
Collagen formation (Homo sapiens)
Assembly of collagen fibrils and other multimeric structures (Homo sapiens)
Release of endostatin-like peptides (Homo sapiens)
Collagen type XVIII [extracellular region] (Homo sapiens)
Collagen alpha-1(XVIII) chains [extracellular region] (Homo sapiens)
3x4Hyp-3Hyp-GalHyl-COL18A1(24-1754) [extracellular region] (Homo sapiens)
Collagen biosynthesis and modifying enzymes (Homo sapiens)
Secretion of collagens (Homo sapiens)
Collagens and tropocollagens [extracellular region] (Homo sapiens)
Non-fibrillar collagens [extracellular region] (Homo sapiens)
Collagen type XVIII [extracellular region] (Homo sapiens)
Collagen alpha-1(XVIII) chains [extracellular region] (Homo sapiens)
3x4Hyp-3Hyp-GalHyl-COL18A1(24-1754) [extracellular region] (Homo sapiens)
Degradation of the extracellular matrix (Homo sapiens)
Collagen degradation (Homo sapiens)
Collagen type XVIII endostatin release (Homo sapiens)
Collagen type XVIII multimer [extracellular region] (Homo sapiens)
Collagen type XVIII [extracellular region] (Homo sapiens)
Collagen alpha-1(XVIII) chains [extracellular region] (Homo sapiens)
3x4Hyp-3Hyp-GalHyl-COL18A1(24-1754) [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:P39060 COL18A1
Gene Names
COL18A1
Chain
signal peptide:1-23, chain:24-1754, chain:1572-1754, chain:-1754
Reference Genes
BioGPS Gene:80781 COL18A1
COSMIC (genes):COL18A1 COL18A1
CTD Gene:80781 COL18A1
dbSNP Gene:80781 COL18A1
ENSEMBL:ENSG00000182871 COL18A1
ENSEMBL_homo_sapiens_GENE:ENSG00000182871.16 COL18A1
HGNC:2195 COL18A1
KEGG Gene (Homo sapiens):80781 COL18A1
Monarch:80781 COL18A1
NCBI Gene:80781 COL18A1
OMIM:120328 COL18A1
UCSC:P39060 COL18A1
Reference Transcript
RefSeq:NM_030582.3 COL18A1
RefSeq:NM_130444.2 COL18A1
RefSeq:NM_130445.3 COL18A1
Other Identifiers
11716281_a_at
11755399_a_at
16923766
209081_PM_s_at
209081_s_at
209082_PM_s_at
209082_s_at
37653_at
3924145
3924146
3924151
3924152
3924153
3924154
3924155
3924156
3924157
3924158
3924164
3924165
3924166
3924168
3924169
3924170
3924172
3924173
3924174
3924175
3924176
3924177
3924178
3924179
3924181
3924182
3924184
3924185
3924188
3924189
3924190
3924192
3924195
3924196
3924197
3924198
3924199
3924203
3924204
3924205
3924206
3924207
3924208
3924209
3924211
3924216
3924217
3924218
3924219
3924221
3924222
3924223
3924224
3924225
3924226
3924227
3924232
8069208
80781
A_14_P105874
A_14_P134074
A_23_P211212
A_24_P57426
GE54150
GO:0001501
GO:0001525
GO:0001886
GO:0005198
GO:0005515
GO:0005576
GO:0005581
GO:0005604
GO:0005615
GO:0005783
GO:0005788
GO:0007155
GO:0007601
GO:0008285
GO:0009410
GO:0009887
GO:0030020
GO:0030154
GO:0030198
GO:0030199
GO:0030312
GO:0030903
GO:0031012
GO:0043226
GO:0046872
GO:0048856
GO:0050877
GO:0051599
GO:0062023
GO:0070062
HMNXSV003018050
Hs.78409.0.S1_3p_s_at
ILMN_1701937
ILMN_1806733
L22548_at
PH_hs_0024936
TC21000245.hg
TC21000793.hg
g2920534_3p_a_at
Participates
as a member of
Collagen alpha-1(XVIII) chains [extracellular region] (Homo sapiens)
Other forms of this molecule
GalHyl-COL18A1(24-1754) [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-GalHyl-COL18A1(24-1754) [endoplasmic reticulum lumen]
3x4Hyp-GlcGalHyl-COL18A1(24-1754) [endoplasmic reticulum lumen]
3x4Hyp-GalHyl-COL18A1(24-1754) [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-GlcGalHyl-COL18A1(24-1754) [endoplasmic reticulum lumen]
GlcGalHyl-COL18A1(24-1754) [endoplasmic reticulum lumen]
COL18A1(24-1754) [endoplasmic reticulum lumen]
3x4Hyp-COL18A1(24-1754) [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-COL18A1(24-1754) [endoplasmic reticulum lumen]
3x4Hyp-5Hyl-COL18A1(24-1754) [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-5Hyl-COL18A1(24-1754) [endoplasmic reticulum lumen]
5Hyl-COL18A1(24-1754) [endoplasmic reticulum lumen]
COL18A1(?-1571) [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL18A1(24-?) [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL18A1(24-?) [extracellular region]
COL18A1(24-?) [extracellular region]
3x4Hyp-COL18A1(24-?) [extracellular region]
GalHyl-COL18A1(24-?) [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL18A1(24-?) [extracellular region]
GlcGalHyl-COL18A1(24-?) [extracellular region]
3x4Hyp-3Hyp-COL18A1(24-?) [extracellular region]
3x4Hyp-5Hyl-COL18A1(24-?) [extracellular region]
5Hyl-COL18A1(24-?) [extracellular region]
3x4Hyp-GalHyl-COL18A1(24-?) [extracellular region]
3x4Hyp-GlcGalHyl-COL18A1(24-?) [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL18A1(24-1754) [extracellular region]
GlcGalHyl-COL18A1(24-1754) [extracellular region]
3x4Hyp-COL18A1(24-1754) [extracellular region]
5Hyl-COL18A1(24-1754) [extracellular region]
GalHyl-COL18A1(24-1754) [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL18A1(24-1754) [extracellular region]
3x4Hyp-GlcGalHyl-COL18A1(24-1754) [extracellular region]
3x4Hyp-3Hyp-COL18A1(24-1754) [extracellular region]
COL18A1(24-1754) [extracellular region]
3x4Hyp-GalHyl-COL18A1(24-1754) [extracellular region]
3x4Hyp-5Hyl-COL18A1(24-1754) [extracellular region]
COL18A1(1572-11754) [extracellular region]
COL18A1(?-1754) [extracellular region]
3x4Hyp-GlcGalHyl-COL18A1(?-1754) [extracellular region]
GlcGalHyl-COL18A1(?-1754) [extracellular region]
3x4Hyp-COL18A1(?-1754) [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL18A1(?-1754) [extracellular region]
5Hyl-COL18A1(?-1754) [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL18A1(?-1754) [extracellular region]
3x4Hyp-5Hyl-COL18A1(?-1754) [extracellular region]
3x4Hyp-GalHyl-COL18A1(?-1754) [extracellular region]
GalHyl-COL18A1(?-1754) [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL18A1(?-1754) [extracellular region]
3x4Hyp-3Hyp-COL18A1(?-1754) [extracellular region]
Inferred To
Col18a1 [extracellular region]
(Rattus norvegicus)
3x4Hyp-3Hyp-GalHyl-COL18A1(24-1754) [extracellular region]
(Mus musculus)
COL18A1 [extracellular region]
(Bos taurus)
COL18A1 [extracellular region]
(Canis familiaris)
COL18A1 [extracellular region]
(Sus scrofa)
Modified Residues
Name
(2S,4R)-4-hydroxyproline at unknown position
PsiMod Name
(2S,4R)-4-hydroxyproline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline
Name
(2S,4R)-4-hydroxyproline at unknown position
PsiMod Name
(2S,4R)-4-hydroxyproline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline
Name
(2S,4R)-4-hydroxyproline at unknown position
PsiMod Name
(2S,4R)-4-hydroxyproline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline
Name
(2S,3S)-3-hydroxyproline at unknown position
PsiMod Name
(2S,3S)-3-hydroxyproline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to 3-hydroxy-L-proline.
Name
O5-galactosyl-L-hydroxylysine at unknown position
PsiMod Name
O5-galactosyl-L-hydroxylysine
PsiMod Definition
A protein modification that effectively converts an L-lysine residue to O5-galactosyl-L-hydroxylysine.
Cross References
RefSeq
NP_085059.2
,
NP_569711.2
,
NP_569712.2
OpenTargets
ENSG00000182871
HPA
ENSG00000182871-COL18A1
GeneCards
P39060
Ensembl
ENSG00000182871
,
ENST00000651438
,
ENST00000359759
,
ENSP00000347665
,
ENSP00000352798
,
ENSP00000498485
,
ENST00000355480
PRO
P39060
Pharos - Targets
P39060
Orphanet
15766
HMDB Protein
HMDBP13479
PDB
3HON
,
3HSH
,
1BNL
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
ChEBI:28304 HEPARIN
0.564
2
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