PPM1A protein phosphatase binds phosphorylated SMAD2/3

Stable Identifier
R-HSA-2187388
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
PPM1A protein phosphatase binds phosphorylated SMAD2/3
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

PPM1A protein phosphatase binds phosphorylated SMAD2 and SMAD3 in the nucleus.

Literature References
PubMed ID Title Journal Year
16751101 PPM1A functions as a Smad phosphatase to terminate TGFbeta signaling

Wrighton, KH, Shi, Y, Liang, YY, Brunicardi, FC, Duan, X, Feng, XH, Chen, YG, Su, Y, Lin, X, Hu, M, Meng, A, Wang, J, Davis, CM, Long, J

Cell 2006
Participants
Input
Output
Participates
as an event of
Orthologous Events
PPM1A protein phosphatase binds phosphorylated SMAD2/3 (Bos taurus)
PPM1A protein phosphatase binds phosphorylated SMAD2/3 (Caenorhabditis elegans)
PPM1A protein phosphatase binds phosphorylated SMAD2/3 (Canis familiaris)
PPM1A protein phosphatase binds phosphorylated SMAD2/3 (Danio rerio)
PPM1A protein phosphatase binds phosphorylated SMAD2/3 (Drosophila melanogaster)
PPM1A protein phosphatase binds phosphorylated SMAD2/3 (Mus musculus)
PPM1A protein phosphatase binds phosphorylated SMAD2/3 (Rattus norvegicus)
PPM1A protein phosphatase binds phosphorylated SMAD2/3 (Sus scrofa)
PPM1A protein phosphatase binds phosphorylated SMAD2/3 (Xenopus tropicalis)
Authored
Orlic-Milacic, M  (2012-04-05)
Reviewed
Huang, T  (2012-05-14)
Contreras, O  (2022-05-02)
Created
Orlic-Milacic, M  (2012-04-10)
Cite Us!