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PMEPA1 [early endosome membrane]
Stable Identifier
R-HSA-2187347
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
early endosome membrane
Synonyms
Transmembrane prostate androgen-induced protein, TMEPAI, STAG1
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by TGFB family members (Homo sapiens)
Signaling by TGF-beta Receptor Complex (Homo sapiens)
TGF-beta receptor signaling activates SMADs (Homo sapiens)
Downregulation of TGF-beta receptor signaling (Homo sapiens)
PMEPA1 sequesters phosphorylated SMAD2/3 (Homo sapiens)
PMEPA1 [early endosome membrane] (Homo sapiens)
p-2S-SMAD2/3:PMEPA1 [early endosome membrane] (Homo sapiens)
PMEPA1 [early endosome membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q969W9 PMEPA1
Gene Names
PMEPA1, STAG1, TMEPAI
Chain
chain:1-287
Reference Genes
BioGPS Gene:56937 PMEPA1
COSMIC (genes):PMEPA1 PMEPA1
COSMIC (genes):STAG1 PMEPA1
CTD Gene:56937 PMEPA1
dbSNP Gene:56937 PMEPA1
ENSEMBL:ENSG00000124225 PMEPA1
HGNC:14107 PMEPA1
KEGG:hsa:56937 PMEPA1
Monarch:56937 PMEPA1
NCBI Gene:56937 PMEPA1
OMIM:606564 PMEPA1
UCSC:Q969W9 PMEPA1
Reference Transcript
RefSeq:NM_199170.2 PMEPA1
RefSeq:NM_020182.4 PMEPA1
RefSeq:NM_199169.2 PMEPA1
RefSeq:NM_199171.2 PMEPA1
RefSeq:NM_001255976.1 PMEPA1
Other Identifiers
11716149_a_at
11716150_a_at
11716151_a_at
16920671
217875_PM_s_at
217875_s_at
222449_PM_at
222449_at
222450_PM_at
222450_at
3911218
3911219
3911220
3911221
3911222
3911223
3911224
3911225
3911226
3911227
3911228
3911229
3911230
3911231
3911233
3911237
3911238
3911246
3911252
3911259
3911260
3911261
3911262
3911263
46644_at
56937
65880_at
8067233
91095_s_at
91318_r_at
A_23_P57089
A_24_P413126
A_33_P3403867
GE56124
GE79441
GO:0000139
GO:0005515
GO:0005768
GO:0005794
GO:0005886
GO:0009968
GO:0010008
GO:0016020
GO:0030512
GO:0030521
GO:0031410
GO:0031901
GO:0043226
GO:0043231
GO:0050699
GO:0060392
GO:0070412
GO:0140311
GO:0140313
HMNXSV003038599
Hs.83883.0.S2_3p_at
Hs.83883.0.S3_3p_at
ILMN_1657823
ILMN_1675858
ILMN_1734276
ILMN_2309156
PH_hs_0004780
TC20000980.hg
TC20001671.hg
g9910497_3p_a_at
Participates
as a component of
p-2S-SMAD2/3:PMEPA1 [early endosome membrane] (Homo sapiens)
as an input of
PMEPA1 sequesters phosphorylated SMAD2/3 (Homo sapiens)
Other forms of this molecule
PMEPA1 [plasma membrane]
Inferred To
Pmepa1 [early endosome membrane]
(Mus musculus)
Pmepa1 [early endosome membrane]
(Rattus norvegicus)
PMEPA1 [early endosome membrane]
(Bos taurus)
PMEPA1 [early endosome membrane]
(Canis familiaris)
PMEPA1 [early endosome membrane]
(Gallus gallus)
PMEPA1 [early endosome membrane]
(Sus scrofa)
pmepa1 [early endosome membrane]
(Danio rerio)
pmepa1 [early endosome membrane]
(Xenopus tropicalis)
Cross References
RefSeq
NP_064567.2
,
NP_954639.1
,
NP_954638.1
,
NP_001242905.1
,
NP_954640.1
ENSEMBL
ENSP00000379161
,
ENST00000347215
,
ENST00000265626
,
ENSP00000345826
,
ENSP00000379159
,
ENST00000395816
,
ENST00000395814
,
ENST00000341744
,
ENSP00000265626
,
ENSP00000344014
OpenTargets
ENSG00000124225
HPA
ENSG00000124225-PMEPA1
PRO
Q969W9
Pharos - Targets
Q969W9
GlyGen
Q969W9
HMDB Protein
HMDBP14553
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P0DTD8 NS7B
0.547
2
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