SMAD2/3:SMAD4 heterotrimer binds SMAD binding site in the promoter of JUNB transcription factor and in cooperation with AP-1 transcription factors, which bind to an adjacent promoter element, stimulates transcription of JUNB gene (Wong et al. 1999).
Wong, C, Wang, XF, Datto, MB, Rougier-Chapman, EM, Li, JM, Liberati, NT, Frederick, JP
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