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SCARA5 binds ligands
Stable Identifier
R-HSA-2187266
Type
Reaction [binding]
Species
Homo sapiens
Compartment
extracellular region
,
plasma membrane
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
Vesicle-mediated transport (Homo sapiens)
Binding and Uptake of Ligands by Scavenger Receptors (Homo sapiens)
Scavenging by Class A Receptors (Homo sapiens)
SCARA5 binds ligands (Homo sapiens)
General
SBML
|
BioPAX
Level 2
Level 3
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PDF
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PNG
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PPTX
|
SBGN
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
SCARA5 binds double-stranded RNA (DeWitte-Orr et al. 2010). As inferred from mouse SCARA5 also binds lipopolysaccharide and ferritin. SCARA5 is expressed on epithelial cells.
Literature References
PubMed ID
Title
Journal
Year
20360967
An accessory to the 'Trinity': SR-As are essential pathogen sensors of extracellular dsRNA, mediating entry and leading to subsequent type I IFN responses
DeWitte-Orr, SJ
,
Mossman, KL
,
Bowdish, DM
,
Bauer, CM
,
Collins, SE
PLoS Pathog
2010
Participants
Input
Ligands of SCARA5 [extracellular region]
(Homo sapiens)
SCARA5 trimer [plasma membrane]
(Homo sapiens)
Output
SCARA5:Ligand [plasma membrane]
(Homo sapiens)
Participates
as an event of
Scavenging by Class A Receptors (Homo sapiens)
Inferred From
Scara5 binds ligands (Mus musculus)
Authored
Neyen, C (2013-03-22)
May, B (2013-01-27)
Reviewed
Neyen, C (2013-03-22)
Created
May, B (2012-04-07)
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