Activated PKC-alpha activate MMP3

Stable Identifier
R-HSA-2179413
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
plasma membrane, extracellular region
ReviewStatus
5/5
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Activated PKC-alpha activate MMP3
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Gastrin activated PKC pathway leads to the induction of matrix metalloproteinase 3 (MMP3) synthesis (Reuben et al. 2002). The cleavage and autocatalysis steps to obtain the fully activated form of MMP3 have been omitted here.
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Output
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as an event of
Catalyst Activity

diacylglycerol-dependent serine/threonine kinase activity of Protein Kinase C, alpha type: DAG [plasma membrane]

Physical Entity
Protein Kinase C, alpha type: DAG [plasma membrane] (Homo sapiens)
Activity
diacylglycerol-dependent serine/threonine kinase activity (GO:0004697)
Orthologous Events
Activated PKC-alpha activate MMP3 (Caenorhabditis elegans)
Activated PKC-alpha activate MMP3 (Canis familiaris)
Activated PKC-alpha activate MMP3 (Drosophila melanogaster)
Activated PKC-alpha activate MMP3 (Gallus gallus)
Activated PKC-alpha activate MMP3 (Mus musculus)
Activated PKC-alpha activate MMP3 (Rattus norvegicus)
Activated PKC-alpha activate MMP3 (Sus scrofa)
Authored
Tripathi, S  (2012-04-04)
Jassal, B  (2012-04-04)
Reviewed
D'Eustachio, P  (2012-04-23)
Created
Jassal, B  (2012-04-04)
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