Activated PKC-alpha activate MMP3

Stable Identifier
R-HSA-2179413
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
plasma membrane, extracellular region
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Activated PKC-alpha activate MMP3
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Gastrin activated PKC pathway leads to the induction of matrix metalloproteinase 3 (MMP3) synthesis (Reuben et al. 2002). The cleavage and autocatalysis steps to obtain the fully activated form of MMP3 have been omitted here.

Literature References
Participants
Input
Output
Participates
as an event of
Catalyst Activity

protein kinase C activity of Protein Kinase C, alpha type: DAG [plasma membrane]

Physical Entity
Protein Kinase C, alpha type: DAG [plasma membrane] (Homo sapiens)
Activity
protein kinase C activity (GO:0004697)
Orthologous Events
Activated PKC-alpha activate MMP3 (Caenorhabditis elegans)
Activated PKC-alpha activate MMP3 (Canis familiaris)
Activated PKC-alpha activate MMP3 (Drosophila melanogaster)
Activated PKC-alpha activate MMP3 (Gallus gallus)
Activated PKC-alpha activate MMP3 (Mus musculus)
Activated PKC-alpha activate MMP3 (Rattus norvegicus)
Authored
Tripathi, S  (2012-04-04)
Jassal, B  (2012-04-04)
Reviewed
D'Eustachio, P  (2012-04-23)
Created
Jassal, B  (2012-04-04)
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