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3x4Hyp-COL28A1 [endoplasmic reticulum lumen]
Stable Identifier
R-HSA-2172946
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum lumen
Synonyms
3x4Hyp-COL28A1(24-1125), 4-hydroxyprolyl collagen alpha-1(XXVIII) chain, COL28A1, COSA1_HUMAN
Locations in the PathwayBrowser
Expand all
Extracellular matrix organization (Homo sapiens)
Collagen formation (Homo sapiens)
Collagen biosynthesis and modifying enzymes (Homo sapiens)
Collagen chain trimerization (Homo sapiens)
Association of procollagen type XVIII (Homo sapiens)
Alpha-1(XXVIII) chains [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-COL28A1 [endoplasmic reticulum lumen] (Homo sapiens)
C-linked procollagen type XXVIII trimer [endoplasmic reticulum lumen] (Homo sapiens)
Alpha-1(XXVIII) chains [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-COL28A1 [endoplasmic reticulum lumen] (Homo sapiens)
Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen (Homo sapiens)
Prolyl 3-hydroxylases:Fe2+:4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-COL28A1 [endoplasmic reticulum lumen] (Homo sapiens)
P3HB binds 4-Hyp-collagen propeptides (Homo sapiens)
4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-COL28A1 [endoplasmic reticulum lumen] (Homo sapiens)
Prolyl 3-hydroxylases:Fe2+:4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-COL28A1 [endoplasmic reticulum lumen] (Homo sapiens)
P4HB:4-Hyp collagen propeptides dissociates (Homo sapiens)
4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-COL28A1 [endoplasmic reticulum lumen] (Homo sapiens)
4-Hyp collagen propeptides:P4HB [endoplasmic reticulum lumen] (Homo sapiens)
4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-COL28A1 [endoplasmic reticulum lumen] (Homo sapiens)
Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines (Homo sapiens)
Lysyl hydroxylases:Lysyl hydroxylase procollagen substrates [endoplasmic reticulum membrane] (Homo sapiens)
Lysyl hydroxylase procollagen substrates [endoplasmic reticulum lumen] (Homo sapiens)
4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-COL28A1 [endoplasmic reticulum lumen] (Homo sapiens)
Procollagen triple helix formation (Homo sapiens)
Collagen and procollagen triple helices:Serpin H1 [endoplasmic reticulum lumen] (Homo sapiens)
Collagen and procollagen triple helices [endoplasmic reticulum lumen] (Homo sapiens)
Non-fibrillar collagens [endoplasmic reticulum lumen] (Homo sapiens)
Tropocollagen type XXVIII [endoplasmic reticulum lumen] (Homo sapiens)
Alpha-1(XXVIII) chains [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-COL28A1 [endoplasmic reticulum lumen] (Homo sapiens)
Procollagen C-linked trimers [endoplasmic reticulum lumen] (Homo sapiens)
C-linked procollagen type XXVIII trimer [endoplasmic reticulum lumen] (Homo sapiens)
Alpha-1(XXVIII) chains [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-COL28A1 [endoplasmic reticulum lumen] (Homo sapiens)
Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines (Homo sapiens)
4-Hyp collagen propeptides:P4HB [endoplasmic reticulum lumen] (Homo sapiens)
4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-COL28A1 [endoplasmic reticulum lumen] (Homo sapiens)
Secretion of collagens (Homo sapiens)
Collagens and tropocollagens:Serpin H1 [endoplasmic reticulum lumen] (Homo sapiens)
Collagens and tropocollagens [endoplasmic reticulum lumen] (Homo sapiens)
Non-fibrillar collagens [endoplasmic reticulum lumen] (Homo sapiens)
Tropocollagen type XXVIII [endoplasmic reticulum lumen] (Homo sapiens)
Alpha-1(XXVIII) chains [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-COL28A1 [endoplasmic reticulum lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q2UY09 COL28A1
Gene Names
COL28A1, COL28
Chain
signal peptide:1-23, chain:24-1125
Reference Genes
BioGPS Gene:340267 COL28A1
COSMIC (genes):COL28A1 COL28A1
CTD Gene:340267 COL28A1
dbSNP Gene:340267 COL28A1
ENSEMBL:ENSG00000215018 COL28A1
ENSEMBL_homo_sapiens_GENE:ENSG00000215018.10 COL28A1
HGNC:22442 COL28A1
KEGG Gene (Homo sapiens):340267 COL28A1
Monarch:340267 COL28A1
NCBI Gene:340267 COL28A1
OMIM:609996 COL28A1
UCSC:Q2UY09 COL28A1
Reference Transcript
RefSeq:NM_001037763.2 COL28A1
RefSeq:XM_011515359.2 COL28A1
RefSeq:XM_011515363.2 COL28A1
RefSeq:XM_017012132.1 COL28A1
RefSeq:XM_011515358.2 COL28A1
RefSeq:XM_011515360.2 COL28A1
RefSeq:XM_017012131.1 COL28A1
Other Identifiers
11738396_a_at
17055140
242345_PM_at
242345_at
3037842
3037843
3037844
3037845
3037846
3037847
3037849
3037851
3037854
3037856
3037864
3037865
3037870
3037871
3037873
3037875
3037877
3037879
3037880
3037882
3037883
3037886
3037893
3037894
3037896
3037897
3037901
3037902
3037903
3037904
3037905
3037906
3037907
3037908
340267
8138157
84565_s_at
A_33_P3243787
GE88261
GO:0004867
GO:0005198
GO:0005576
GO:0005581
GO:0005588
GO:0005604
GO:0005615
GO:0005783
GO:0005788
GO:0007155
GO:0008201
GO:0030020
GO:0030198
GO:0030199
GO:0030312
GO:0030414
GO:0031012
GO:0043226
GO:0062023
GO:0098772
HMNXSV003021672
Hs.170023.0.A1_3p_at
PH_hs_0034088
TC07001138.hg
Participates
as a member of
Alpha-1(XXVIII) chains [endoplasmic reticulum lumen] (Homo sapiens)
as a candidate of
4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
Other forms of this molecule
GalHyl-COL28A1 [extracellular region]
3x4Hyp-5Hyl-COL28A1 [extracellular region]
3x4Hyp-GalHyl-COL28A1 [extracellular region]
3x4Hyp-3Hyp-COL28A1 [extracellular region]
GlcGalHyl-COL28A1 [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL28A1 [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL28A1 [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL28A1 [extracellular region]
COL28A1 [extracellular region]
3x4Hyp-COL28A1 [extracellular region]
3x4Hyp-GlcGalHyl-COL28A1 [extracellular region]
5Hyl-COL28A1 [extracellular region]
GlcGalHyl-COL28A1 [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-GlcGalHyl-COL28A1 [endoplasmic reticulum lumen]
3x4Hyp-GalHyl-COL28A1 [endoplasmic reticulum lumen]
GalHyl-COL28A1 [endoplasmic reticulum lumen]
3x4Hyp-GlcGalHyl-COL28A1 [endoplasmic reticulum lumen]
5Hyl-COL28A1 [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-5Hyl-COL28A1 [endoplasmic reticulum lumen]
3x4Hyp-5Hyl-COL28A1 [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-COL28A1 [endoplasmic reticulum lumen]
COL28A1 [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-GalHyl-COL28A1 [endoplasmic reticulum lumen]
Inferred To
Col28a1 [endoplasmic reticulum lumen]
(Mus musculus)
Col28a1 [endoplasmic reticulum lumen]
(Rattus norvegicus)
Homologues of 3x4Hyp-COL28A1 [endoplasmic reticulum lumen]
(Danio rerio)
col28a1b [endoplasmic reticulum lumen]
(Danio rerio)
col28a1a [endoplasmic reticulum lumen]
(Danio rerio)
COL28A1 [endoplasmic reticulum lumen]
(Bos taurus)
COL28A1 [endoplasmic reticulum lumen]
(Canis familiaris)
COL28A1 [endoplasmic reticulum lumen]
(Sus scrofa)
Modified Residues
Name
(2S,4R)-4-hydroxyproline at unknown position
PsiMod Name
(2S,4R)-4-hydroxyproline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline
Name
(2S,4R)-4-hydroxyproline at unknown position
PsiMod Name
(2S,4R)-4-hydroxyproline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline
Name
(2S,4R)-4-hydroxyproline at unknown position
PsiMod Name
(2S,4R)-4-hydroxyproline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline
Cross References
RefSeq
XP_016867621.1
,
XP_016867620.1
,
XP_011513661.1
,
XP_011513665.1
,
NP_001032852.2
,
XP_011513660.1
,
XP_011513662.1
OpenTargets
ENSG00000215018
GeneCards
Q2UY09
HPA
ENSG00000215018-COL28A1
Ensembl
ENST00000399429
,
ENSG00000215018
,
ENSP00000382356
PRO
Q2UY09
Pharos - Targets
Q2UY09
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