Hemopexin binds Heme b

Stable Identifier
R-HSA-2168886
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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Hemopexin binds either ferriheme b or ferroheme b, however the stability of the complex containing ferriheme b is greater than the stability of the complex containing ferroheme b (Morgan 1976, Pasternack et al. 1983, Solar et al. 1989, Miller and Shaklai 1999, Rosell et al. 2005, Mauk and Mauk 2010).

Literature References
PubMed ID Title Journal Year
6849882 Hemin binding to serum proteins and the catalysis of interprotein transfer

Pasternack, RF, Gibbs, EJ, Hoeflin, E, Kosar, WP, Kubera, G, Skowronek, CA, Wong, NM, Muller-Eberhard, U

Biochemistry 1983
20430887 Metal ions and electrolytes regulate the dissociation of heme from human hemopexin at physiological pH

Mauk, MR, Mauk, AG

J Biol Chem 2010
10381560 Kinetics of hemin distribution in plasma reveals its role in lipoprotein oxidation

Miller, YI, Shaklai, N

Biochim Biophys Acta 1999
1008494 The binding and transport of heme by hemopexin

Morgan, WT

Ann Clin Res 1976
2806549 Serum proteins as mediators of hemin efflux from red cell membranes: specificity of hemopexin

Solar, I, Muller-Eberhard, U, Shaklai, N

FEBS Lett 1989
15697213 pH- and metal ion-linked stability of the hemopexin-heme complex

Rosell, FI, Mauk, MR, Mauk, AG

Biochemistry 2005
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