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CD163 [plasma membrane]
Stable Identifier
R-HSA-2168868
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Scavenger receptor cysteine-rich type 1 protein M130, C163A_HUMAN
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Parasitic Infection Pathways (Homo sapiens)
Leishmania infection (Homo sapiens)
Leishmania parasite growth and survival (Homo sapiens)
Anti-inflammatory response favouring Leishmania parasite infection (Homo sapiens)
CD163 mediating an anti-inflammatory response (Homo sapiens)
CD163 gene produces CD163 protein (Homo sapiens)
CD163 [plasma membrane] (Homo sapiens)
p-S,T-ADAM17(215-827):Zn2+ cleaves CD163 (Homo sapiens)
CD163 [plasma membrane] (Homo sapiens)
Vesicle-mediated transport (Homo sapiens)
Binding and Uptake of Ligands by Scavenger Receptors (Homo sapiens)
Scavenging of heme from plasma (Homo sapiens)
Haptoglobin:Hemoglobin binds CD163 (Homo sapiens)
CD163 [plasma membrane] (Homo sapiens)
Hemoglobin:Haptoglobin:CD163 [plasma membrane] (Homo sapiens)
CD163 [plasma membrane] (Homo sapiens)
Hemoglobin:Haptoglobin:CD163 is endocytosed (Homo sapiens)
Hemoglobin:Haptoglobin:CD163 [plasma membrane] (Homo sapiens)
CD163 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q86VB7 CD163
Gene Names
CD163, M130
Chain
signal peptide:1-41, chain:42-1156, chain:42-
Reference Genes
BioGPS Gene:9332 CD163
COSMIC (genes):CD163 CD163
CTD Gene:9332 CD163
dbSNP Gene:9332 CD163
ENSEMBL:ENSG00000177575 CD163
HGNC:1631 CD163
KEGG:hsa:9332 CD163
Monarch:9332 CD163
NCBI Gene:9332 CD163
OMIM:605545 CD163
UCSC:Q86VB7 CD163
Reference Transcript
RefSeq:NM_203416.3 CD163
RefSeq:NM_004244.5 CD163
RefSeq:XM_017020231.1 CD163
Other Identifiers
11728679_a_at
16760792
203645_PM_s_at
203645_s_at
215049_PM_x_at
215049_x_at
216233_PM_at
216233_at
31438_s_at
3442705
3442707
3442708
3442710
3442713
3442714
3442715
3442716
3442717
3442718
3442719
3442720
3442722
3442723
3442725
3442726
3442727
3442728
3442729
3442733
3442734
3442736
3442739
3442740
3442742
3442743
36884_at
7960794
89949_r_at
9332
A_23_P33723
GE60372
GO:0005044
GO:0005515
GO:0005576
GO:0005829
GO:0005886
GO:0006953
GO:0006954
GO:0009897
GO:0016020
GO:0016192
GO:0030666
GO:0038024
GO:0097110
HMNXSV003015821
Hs.74076.2.S1_3p_a_at
ILMN_1722622
ILMN_1733270
ILMN_2379599
PH_hs_0004236
TC12001162.hg
Z22970_at
Participates
as an output of
CD163 gene produces CD163 protein (Homo sapiens)
as an input of
p-S,T-ADAM17(215-827):Zn2+ cleaves CD163 (Homo sapiens)
Haptoglobin:Hemoglobin binds CD163 (Homo sapiens)
as a component of
Hemoglobin:Haptoglobin:CD163 [plasma membrane] (Homo sapiens)
Other forms of this molecule
CD163(1051-1156) [plasma membrane]
sCD163 [extracellular region]
sCD163 [cytosol]
CD163 [endocytic vesicle membrane]
Inferred To
Cd163 [plasma membrane]
(Mus musculus)
Cd163 [plasma membrane]
(Rattus norvegicus)
Ghost homologue of CD163 [plasma membrane]
(Danio rerio)
Ghost homologue of CD163 [plasma membrane]
(Gallus gallus)
CD163 [plasma membrane]
(Bos taurus)
CD163 [plasma membrane]
(Canis familiaris)
CD163 [plasma membrane]
(Sus scrofa)
Cross References
ENSEMBL
ENSP00000403885
,
ENST00000359156
,
ENSP00000352071
,
ENST00000432237
OpenTargets
ENSG00000177575
HPA
ENSG00000177575-CD163
PRO
Q86VB7
Pharos - Targets
Q86VB7
HMDB Protein
HMDBP07476
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P12314 FCGR1A
3
FCGR1A [clathrin-coated endocytic vesicle membrane]
(R-HSA-1236781)
FCGR1A [early endosome membrane]
(R-HSA-1236890)
FCGR1A [plasma membrane]
(R-HSA-197835)
0.556
3
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