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HPX [extracellular region]
Stable Identifier
R-HSA-2168860
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
Hemopexin, HEMO_HUMAN
Locations in the PathwayBrowser
Expand all
Vesicle-mediated transport (Homo sapiens)
Binding and Uptake of Ligands by Scavenger Receptors (Homo sapiens)
Scavenging of heme from plasma (Homo sapiens)
Ferriheme is transferred from Albumin to Hemopexin (Homo sapiens)
HPX [extracellular region] (Homo sapiens)
HPX:ferriheme b [extracellular region] (Homo sapiens)
HPX [extracellular region] (Homo sapiens)
Ferriheme is transferred from Methemoglobin to Hemopexin (Homo sapiens)
HPX [extracellular region] (Homo sapiens)
HPX:ferriheme b [extracellular region] (Homo sapiens)
HPX [extracellular region] (Homo sapiens)
Hemopexin binds Hemes (Homo sapiens)
HPX [extracellular region] (Homo sapiens)
HPX:Hemes [extracellular region] (Homo sapiens)
HPX [extracellular region] (Homo sapiens)
LRP1 (CD91) binds Hemopexin:heme (Homo sapiens)
HPX:Hemes [extracellular region] (Homo sapiens)
HPX [extracellular region] (Homo sapiens)
LRP1:Hemopexin:heme [plasma membrane] (Homo sapiens)
HPX:Hemes [extracellular region] (Homo sapiens)
HPX [extracellular region] (Homo sapiens)
LRP1:Hemopexin:heme is endocytosed (Homo sapiens)
LRP1:Hemopexin:heme [plasma membrane] (Homo sapiens)
HPX:Hemes [extracellular region] (Homo sapiens)
HPX [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:P02790 HPX
Gene Names
HPX
Chain
signal peptide:1-23, chain:24-462
Reference Genes
BioGPS Gene:3263 HPX
COSMIC (genes):HPX HPX
CTD Gene:3263 HPX
dbSNP Gene:3263 HPX
ENSEMBL:ENSG00000110169 HPX
HGNC:5171 HPX
KEGG:hsa:3263 HPX
Monarch:3263 HPX
NCBI Gene:3263 HPX
OMIM:142290 HPX
UCSC:P02790 HPX
Reference Transcript
RefSeq:NM_000613.2 HPX
Other Identifiers
11718783_a_at
11750047_a_at
11761784_at
16735054
210013_PM_at
210013_at
3263
3360875
3360876
3360877
3360878
3360879
3360880
3360881
3360883
3360884
3360885
3360886
3360887
3360888
3360889
3360890
3360891
3360892
3360893
3360894
3360895
3360896
3360897
3360898
39763_PM_at
39763_at
7946167
A_23_P161998
GE60511
GO:0002639
GO:0002925
GO:0005215
GO:0005515
GO:0005576
GO:0005615
GO:0006879
GO:0015232
GO:0015886
GO:0020027
GO:0030312
GO:0031012
GO:0042168
GO:0043226
GO:0046872
GO:0051246
GO:0060332
GO:0060333
GO:0060335
GO:0062023
GO:0070062
GO:0071682
GO:0072562
HMNXSV003034618
ILMN_1668593
M36803_at
PH_hs_0019843
TC11001356.hg
g13529280_3p_s_at
Participates
as an input of
Ferriheme is transferred from Methemoglobin to Hemopexin (Homo sapiens)
Hemopexin binds Hemes (Homo sapiens)
Ferriheme is transferred from Albumin to Hemopexin (Homo sapiens)
as a component of
HPX:Hemes [extracellular region] (Homo sapiens)
HPX:ferriheme b [extracellular region] (Homo sapiens)
Other forms of this molecule
HPX [endocytic vesicle lumen]
Inferred To
Homologues of HPX [extracellular region]
(Caenorhabditis elegans)
Homologues of HPX [extracellular region]
(Drosophila melanogaster)
HPX [extracellular region]
(Bos taurus)
HPX [extracellular region]
(Caenorhabditis elegans)
HPX [extracellular region]
(Drosophila melanogaster)
HPX [extracellular region]
(Mus musculus)
HPX [extracellular region]
(Rattus norvegicus)
HPX [extracellular region]
(Sus scrofa)
HPX [extracellular region]
(Xenopus tropicalis)
Cross References
ENSEMBL
ENSP00000265983
,
ENST00000265983
OpenTargets
ENSG00000110169
HPA
ENSG00000110169-HPX
PRO
P02790
Pharos - Targets
P02790
GlyGen
P02790
HMDB Protein
HMDBP01628
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q8IXK2 GALNT12
6
GALNT12 Y395* [Golgi membrane]
(R-HSA-5138160)
GALNT12 M1I [Golgi membrane]
(R-HSA-5138151)
GALNT12 Y396C [Golgi membrane]
(R-HSA-5138168)
GALNT12 D303N [Golgi membrane]
(R-HSA-5138141)
GALNT12 T491M [Golgi membrane]
(R-HSA-5138143)
GALNT12 [Golgi membrane]
(R-HSA-913627)
0.641
3
UniProt:Q9H8H2 DDX31
0.527
2
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