4xPALM-C-p-2S-ABCA1 tetramer binds APOA1

Stable Identifier
R-HSA-216727
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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ABCA1 associated with the plasma membrane binds extracellular apolipoprotein A-I (APOA1), forming a membrane-associated complex. The predominant form of ABCA1 is a heterotetramer (Denis et al. 2004), although studies in model systems in vitro are consistent with the hypothesis that the protein may also occur as a dimer (Trompier et al. 2006).

Literature References
PubMed ID Title Journal Year
15280376 Characterization of oligomeric human ATP binding cassette transporter A1. Potential implications for determining the structure of nascent high density lipoprotein particles

Denis, M, Haidar, B, Marcil, M, Bouvier, M, Krimbou, L, Genest, J

J Biol Chem 2004
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