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ITGB8 [plasma membrane]
Stable Identifier
R-HSA-216318
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Integrin beta 8
Locations in the PathwayBrowser
Expand all
Extracellular matrix organization (Homo sapiens)
Elastic fibre formation (Homo sapiens)
Molecules associated with elastic fibres (Homo sapiens)
Latent TGF-beta-1 binds integrins (Homo sapiens)
LAP1 binding-integrins [plasma membrane] (Homo sapiens)
Integrin alphaVbeta8 [plasma membrane] (Homo sapiens)
ITGB8 [plasma membrane] (Homo sapiens)
LTBP1:TGFB1:LAP1:LAP1-binding integrins [plasma membrane] (Homo sapiens)
LAP1 binding-integrins [plasma membrane] (Homo sapiens)
Integrin alphaVbeta8 [plasma membrane] (Homo sapiens)
ITGB8 [plasma membrane] (Homo sapiens)
Latent TGF-beta-3 binds integrins (Homo sapiens)
LAP3-binding integrins [plasma membrane] (Homo sapiens)
Integrin alphaVbeta8 [plasma membrane] (Homo sapiens)
ITGB8 [plasma membrane] (Homo sapiens)
TGF-beta-3:LAP3:LAP3-binding integrins [plasma membrane] (Homo sapiens)
LAP3-binding integrins [plasma membrane] (Homo sapiens)
Integrin alphaVbeta8 [plasma membrane] (Homo sapiens)
ITGB8 [plasma membrane] (Homo sapiens)
Integrin cell surface interactions (Homo sapiens)
VTN (vitronectin) binds Integrin alphaVbeta3, alphaVbeta5, alphaVbeta8 (Homo sapiens)
Integrin alphaVbeta3, 5, 8 [plasma membrane] (Homo sapiens)
Integrin alphaVbeta8 [plasma membrane] (Homo sapiens)
ITGB8 [plasma membrane] (Homo sapiens)
VTN:Integrin alphaVbeta3, 5, 8 [plasma membrane] (Homo sapiens)
Integrin alphaVbeta3, 5, 8 [plasma membrane] (Homo sapiens)
Integrin alphaVbeta8 [plasma membrane] (Homo sapiens)
ITGB8 [plasma membrane] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by TGFB family members (Homo sapiens)
Signaling by TGF-beta Receptor Complex (Homo sapiens)
TGF-beta receptor signaling activates SMADs (Homo sapiens)
Latent TGF-beta-1 binds integrins (Homo sapiens)
LAP1 binding-integrins [plasma membrane] (Homo sapiens)
Integrin alphaVbeta8 [plasma membrane] (Homo sapiens)
ITGB8 [plasma membrane] (Homo sapiens)
LTBP1:TGFB1:LAP1:LAP1-binding integrins [plasma membrane] (Homo sapiens)
LAP1 binding-integrins [plasma membrane] (Homo sapiens)
Integrin alphaVbeta8 [plasma membrane] (Homo sapiens)
ITGB8 [plasma membrane] (Homo sapiens)
Latent TGF-beta-3 binds integrins (Homo sapiens)
LAP3-binding integrins [plasma membrane] (Homo sapiens)
Integrin alphaVbeta8 [plasma membrane] (Homo sapiens)
ITGB8 [plasma membrane] (Homo sapiens)
TGF-beta-3:LAP3:LAP3-binding integrins [plasma membrane] (Homo sapiens)
LAP3-binding integrins [plasma membrane] (Homo sapiens)
Integrin alphaVbeta8 [plasma membrane] (Homo sapiens)
ITGB8 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P26012 ITGB8
Gene Names
ITGB8
Chain
signal peptide:1-42, chain:43-769
Reference Genes
BioGPS Gene:3696 ITGB8
COSMIC (genes):ITGB8 ITGB8
CTD Gene:3696 ITGB8
dbSNP Gene:3696 ITGB8
ENSEMBL:ENSG00000105855 ITGB8
HGNC:6163 ITGB8
KEGG:hsa:3696 ITGB8
Monarch:3696 ITGB8
NCBI Gene:3696 ITGB8
OMIM:604160 ITGB8
UCSC:P26012 ITGB8
Reference Transcript
RefSeq:NM_002214.2 ITGB8
RefSeq:XM_017012183.1 ITGB8
RefSeq:XM_017012180.1 ITGB8
RefSeq:XM_017012182.1 ITGB8
RefSeq:XM_017012181.1 ITGB8
RefSeq:XM_011515396.1 ITGB8
RefSeq:XM_017012179.1 ITGB8
RefSeq:XM_017012178.1 ITGB8
Other Identifiers
11722503_at
11747473_a_at
11749103_a_at
11751989_a_at
1563010_PM_at
1563010_at
17043982
205816_PM_at
205816_at
211488_PM_s_at
211488_s_at
226189_PM_at
226189_at
242982_3p_x_at
242982_PM_x_at
242982_x_at
2991861
2991862
2991863
2991870
2991871
2991872
2991884
2991885
2991886
2991887
2991888
2991892
2991894
2991897
2991898
2991899
2991901
2991902
2991903
2991907
2991908
2991909
2991920
2991921
2991936
2991937
2991938
2991939
2991940
2991941
3696
44272_at
50534_at
53497_at
55836_at
60896_at
80778_at
8131666
889_at
A_14_P129597
A_14_P201681
A_14_P201709
A_23_P123060
A_24_P273599
A_24_P929824
GE61428
GE795018
GO:0001570
GO:0001573
GO:0002376
GO:0005102
GO:0005178
GO:0005886
GO:0005925
GO:0006629
GO:0006955
GO:0007155
GO:0007160
GO:0007179
GO:0007229
GO:0008305
GO:0009615
GO:0009986
GO:0010628
GO:0010629
GO:0030154
GO:0034686
GO:0043226
GO:0045766
GO:0046872
GO:0048856
GO:0051216
GO:0060022
GO:0060674
GO:0061520
GO:0070062
GO:0098609
GO:1901135
GO:1990430
HMNXSV003055494
Hs.52620.3.A1_3p_at
Hs.832.0.A1_3p_at
Hs.832.0.A1_3p_s_at
Hs2.385735.1.S1_3p_at
ILMN_1732921
M73780_at
PH_hs_0017236
TC07000125.hg
TC07002184.hg
TC07002185.hg
g12803590_3p_a_at
g4504778_3p_at
Participates
as a component of
Integrin alphaVbeta8 [plasma membrane] (Homo sapiens)
Inferred To
pat-3 [plasma membrane]
(Caenorhabditis elegans)
ITGB8 [plasma membrane]
(Bos taurus)
ITGB8 [plasma membrane]
(Caenorhabditis elegans)
ITGB8 [plasma membrane]
(Canis familiaris)
ITGB8 [plasma membrane]
(Gallus gallus)
ITGB8 [plasma membrane]
(Mus musculus)
ITGB8 [plasma membrane]
(Sus scrofa)
Itgb8 [plasma membrane]
(Rattus norvegicus)
mys [plasma membrane]
(Drosophila melanogaster)
itgb8 [plasma membrane]
(Xenopus tropicalis)
Itgbn [plasma membrane]
(Drosophila melanogaster)
Homologues of ITGB8 [plasma membrane]
(Caenorhabditis elegans)
Homologues of ITGB8 [plasma membrane]
(Drosophila melanogaster)
Cross References
RefSeq
XP_016867672.1
,
XP_016867671.1
,
XP_016867670.1
,
XP_016867667.1
,
XP_011513698.1
,
XP_016867669.1
,
NP_002205.1
,
XP_016867668.1
Guide to Pharmacology - Targets
2462
OpenTargets
ENSG00000105855
ENSEMBL
ENSP00000222573
,
ENST00000222573
,
ENSP00000441561
,
ENST00000537992
,
ENSG00000105855
HPA
ENSG00000105855-ITGB8
GeneCards
ITGB8
PRO
P26012
Pharos - Targets
P26012
GlyGen
P26012
PDB
6OM2
,
8VSD
,
8TCF
,
6UJB
,
6OM1
,
7Y1T
,
6UJA
,
6DJP
,
6UJC
,
8VS6
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