3-methoxy-4-hydroxy-5-decaprenylbenzoic acid (MHDB) is enzymatically decarboxylated to form 2-methoxy-6-decaprenylphenol (DMPhOH). At the present time the enzyme identity is unknown but is thought to be a member of the COQ family. This reaction is inferred from the equivalent reaction in yeast (Casey & Threlfall 1978, Goewert et al. 1981).
Threlfall, DR, Casey, J
Olson, RE, Sippel, CJ, Goewert, RR, Grimm, MF
3-methoxy-4-hydroxy-5-decaprenylbenzoic acid decarboxylase activity of MHDB decarboxylase [mitochondrial matrix]
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