MHDB is decarboxylated to DMPhOH by MHDB decarboxylase

Stable Identifier
R-HSA-2162195
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
mitochondrial matrix
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MHDB is decarboxylated to DMPhOH by MHDB decarboxylase
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3-methoxy-4-hydroxy-5-decaprenylbenzoic acid (MHDB) is enzymatically decarboxylated to form 2-methoxy-6-decaprenylphenol (DMPhOH). At the present time the enzyme identity is unknown but is thought to be a member of the COQ family. This reaction is inferred from the equivalent reaction in yeast (Casey & Threlfall 1978, Goewert et al. 1981).

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Catalyst Activity
Title
3-methoxy-4-hydroxy-5-decaprenylbenzoic acid decarboxylase activity of MHDB decarboxylase [mitochondrial matrix]
Physical Entity
MHDB decarboxylase [mitochondrial matrix]
Activity
3-methoxy-4-hydroxy-5-decaprenylbenzoic acid decarboxylase activity (0036169)
Inferred From
MHHB is decarboxylated to HMPhOH by MHHB decarboxylase (Saccharomyces cerevisiae)
Authored
Williams, MG  (2012-03-19)
Reviewed
Kawamukai, M  (2013-02-05)
Created
Williams, MG  (2012-03-15)