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GADD34:PP1 [cytosol]
Stable Identifier
R-HSA-2162158
Type
Complex
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by TGFB family members (Homo sapiens)
Signaling by TGF-beta Receptor Complex (Homo sapiens)
TGF-beta receptor signaling activates SMADs (Homo sapiens)
Downregulation of TGF-beta receptor signaling (Homo sapiens)
PP1 dephosphorylates TGFBR1 (Homo sapiens)
GADD34:PP1 [cytosol] (Homo sapiens)
TGFB1:p-TGFBR:I-SMAD7:GADD34:PP1:ZFYVE9 [early endosome membrane] (Homo sapiens)
GADD34:PP1 [cytosol] (Homo sapiens)
SMAD7 recruits GADD34:PP1 to phosphorylated TGFBR (Homo sapiens)
GADD34:PP1 [cytosol] (Homo sapiens)
TGFB1:p-TGFBR:I-SMAD7:GADD34:PP1:ZFYVE9 [early endosome membrane] (Homo sapiens)
GADD34:PP1 [cytosol] (Homo sapiens)
Participants
components
PP1 catalytic subunit [cytosol] (Homo sapiens)
PPP1R15A [cytosol] (Homo sapiens)
Participant Of
input
SMAD7 recruits GADD34:PP1 to phosphorylated TGFBR
output
PP1 dephosphorylates TGFBR1
hasComponent
TGFB1:p-TGFBR:I-SMAD7:GADD34:PP1:ZFYVE9 [early endosome membrane]
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