Arachidonic acid is oxidised to 12R-HpETE by ALOX12B

Stable Identifier
R-HSA-2161950
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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The arachidonate 12-lipoxygenase, 12R-type (ALOX12B) oxidises arachidonic acid to 12R-hydroperoxy-eicosatetraenoic acid (12R-HpETE) (Boeglin et al. 1998).

Literature References
PubMed ID Title Journal Year
9618483 A 12R-lipoxygenase in human skin: mechanistic evidence, molecular cloning, and expression

Boeglin, WE, Kim, RB, Brash, AR

Proc Natl Acad Sci U S A 1998
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
arachidonate 12(S)-lipoxygenase activity of ALOX12B:Fe2+ [cytosol]
Physical Entity
Activity
Orthologous Events
Cross References
Rhea
Authored
Reviewed
Created
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