O-acetyl-L-serine-PTGS2 [endoplasmic reticulum membrane]

Stable Identifier
R-HSA-2161824
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum membrane
Synonyms
Ac-PTGS2, acetyl-PTGS2, Cyclooxygenase -2, Ac-COX-2, Ac-Prostaglandin-endoperoxide synthase 2, Ac-Prostaglandin H2 synthase 2, Ac-PGH synthase 2, Ac-PGHS-2, Ac-PHS II
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
8175750 Acetylation of human prostaglandin endoperoxide synthase-2 (cyclooxygenase-2) by aspirin

Lecomte, M, Laneuville, O, Ji, C, DeWitt, DL, Smith, WL

J. Biol. Chem. 1994
External Reference Information
External Reference
UniProt:P35354 PTGS2
Gene Names
PTGS2, COX2
Chain
signal peptide:1-17, chain:18-604
Reference Genes
BioGPS Gene:5743 PTGS2
COSMIC (genes):PTGS2 PTGS2
CTD Gene:5743 PTGS2
dbSNP Gene:5743 PTGS2
ENSEMBL:ENSG00000073756 PTGS2
HGNC:9605 PTGS2
KEGG:hsa:5743 PTGS2
Monarch:5743 PTGS2
NCBI Gene:5743 PTGS2
OMIM:600262 PTGS2
UCSC:P35354 PTGS2
Reference Transcript
Other Identifiers
1069_at
11724036_a_at
11724037_at
11724038_a_at
1554997_PM_a_at
1554997_a_at
16697370
204748_PM_at
204748_at
2448383
2448384
2448385
2448386
2448387
2448389
2448390
2448391
2448392
2448393
2448394
2448395
2448396
2448397
2448398
2448399
2448400
2448401
2448402
2448403
5743
7922976
A_24_P250922
A_24_P77008
D28235_s_at
GE62312
GO:0001516
GO:0004601
GO:0004666
GO:0005515
GO:0005634
GO:0005637
GO:0005640
GO:0005737
GO:0005783
GO:0005788
GO:0005789
GO:0005829
GO:0006629
GO:0006631
GO:0006633
GO:0006693
GO:0006979
GO:0007566
GO:0008217
GO:0009624
GO:0010269
GO:0010575
GO:0016020
GO:0016491
GO:0016701
GO:0016702
GO:0016705
GO:0019371
GO:0019372
GO:0019899
GO:0020037
GO:0022414
GO:0030154
GO:0031394
GO:0031622
GO:0032310
GO:0042127
GO:0042759
GO:0042803
GO:0043005
GO:0043066
GO:0045429
GO:0046457
GO:0046697
GO:0046872
GO:0048856
GO:0050727
GO:0050873
GO:0051213
GO:0071456
GO:0071471
GO:0071498
GO:0071636
GO:0090050
GO:0090271
GO:0090336
GO:0090362
GO:0098754
GO:0098869
GO:0150077
GO:1902219
HMNXSV003013175
Hs2.196384.2.S1_3p_s_at
ILMN_1677511
ILMN_2054297
L15326_s_at
PH_hs_0011595
TC01003638.hg
U04636_rna1_at
g4506264_3p_at
g4506264_3p_x_at
Participates
as a component of
Other forms of this molecule
PTGS2 [endoplasmic reticulum membrane]
Inferred To
ptgs2b [endoplasmic reticulum membrane] (Danio rerio)
ptgs2 [endoplasmic reticulum membrane] (Xenopus tropicalis)
PTGS2 [endoplasmic reticulum membrane] (Bos taurus)
PTGS2 [endoplasmic reticulum membrane] (Gallus gallus)
PTGS2 [endoplasmic reticulum membrane] (Sus scrofa)
Ptgs2 [endoplasmic reticulum membrane] (Mus musculus)
Ptgs2 [endoplasmic reticulum membrane] (Rattus norvegicus)
O-acetyl-L-serine-PTGS2 [endoplasmic reticulum membrane] (Canis familiaris)
Modified Residues
Name
O-acetyl-L-serine at 516
Coordinate
516
PsiMod Name
O-acetyl-L-serine
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-acetyl-L-serine.
Cross References
RefSeq
ZINC - World Drugs
Guide to Pharmacology - Targets
ENSEMBL
OpenTargets
ZINC - FDA approved
ZINC - Substances
ZINC - Biogenic
ZINC target
PRO
PDB
ZINC - Investigational
ZINC - Metabolites
GeneCards
HPA
Pharos - Targets
ZINC - Predictions - Purchasable
HMDB Protein
Interactors (1)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q86V38 Q86V38      0.556 3
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