Reactome | FBLN5 [extracellular region]

FBLN5 [extracellular region]

Stable Identifier

R-HSA-2161278

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

Fibulin-5, FBLN5_HUMAN

Locations in the PathwayBrowser for interactor UniProt:P28300 LOX

Expand all

External Reference Information

External Reference

UniProt:Q9UBX5 FBLN5

Gene Names

FBLN5, DANCE, UNQ184/PRO210

Chain

signal peptide:1-23, chain:24-448

Reference Genes

BioGPS Gene:10516 FBLN5

COSMIC (genes):FBLN5 FBLN5

CTD Gene:10516 FBLN5

dbSNP Gene:10516 FBLN5

ENSEMBL:ENSG00000140092 FBLN5

ENSEMBL_homo_sapiens_GENE:ENSG00000140092.16 FBLN5

HGNC:3602 FBLN5

KEGG Gene (Homo sapiens):10516 FBLN5

Monarch:10516 FBLN5

NCBI Gene:10516 FBLN5

OMIM:604580 FBLN5

UCSC:Q9UBX5 FBLN5

Reference Transcript

RefSeq:NM_006329.3 FBLN5

Other Identifiers

10516

11743043_a_at

16795965

203088_PM_at

203088_at

3576748

3576750

3576751

3576762

3576766

3576767

3576768

3576771

3576774

3576775

3576793

3576794

3576795

3576797

3576800

3576804

3576805

3576806

3576807

39038_at

7980908

A_23_P151805

A_24_P364591

GE55234

GO:0005178

GO:0005198

GO:0005509

GO:0005515

GO:0005576

GO:0005615

GO:0007155

GO:0007160

GO:0030023

GO:0030198

GO:0030312

GO:0031012

GO:0034394

GO:0042803

GO:0043226

GO:0046903

GO:0048251

GO:0062023

GO:0070062

GO:0071953

GO:0098754

GO:2000121

HMNXSV003053773

ILMN_1664176

ILMN_2223941

PH_hs_0001104

TC14001443.hg

g5453649_3p_at

Participates

as a component of

Fibrillins:MFAP2,MFAP5:Tropoelastin aggregate [extracellular region] (Homo sapiens)

as an input of

Tropoelastin associates with microfibrils (Homo sapiens)

as a member of

Fibulins [extracellular region] (Homo sapiens)

Inferred To

Ghost homologue of FBLN5 [extracellular region] (Gallus gallus)

FBLN5 [extracellular region] (Bos taurus)

FBLN5 [extracellular region] (Canis familiaris)

FBLN5 [extracellular region] (Dictyostelium discoideum)

FBLN5 [extracellular region] (Sus scrofa)

Dmel\CG32373 [extracellular region] (Drosophila melanogaster)

fbln5 [extracellular region] (Danio rerio)

fbln5 [extracellular region] (Xenopus tropicalis)

Fbln5 [extracellular region] (Mus musculus)

Fbln5 [extracellular region] (Rattus norvegicus)

Cross References

RefSeq

NP_006320.2

OpenTargets

ENSG00000140092

GeneCards

Q9UBX5

HPA

ENSG00000140092-FBLN5

Ensembl

ENSG00000140092, ENST00000342058, ENSP00000345008

PRO

Q9UBX5

Pharos - Targets

Q9UBX5

Orphanet

16031

HMDB Protein

HMDBP13384

Interactors (18)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q7Z417 NUFP2			0.743	5
UniProt:P15502 ELN	3	ELN(27-?) [extracellular region] (R-HSA-2514783) ELN(?-786) [extracellular region] (R-HSA-2514775) ELN [extracellular region] (R-HSA-1454880)	0.611	3
UniProt:O95967 EFEMP2	1	EFEMP2 [extracellular region] (R-HSA-2161231)	0.611	3
UniProt:P28300 LOX	3	LOX(22-168) [extracellular region] (R-HSA-2022074) LOX(22-417) [extracellular region] (R-HSA-2022071) LOX [extracellular region] (R-HSA-2022085)	0.573	2
UniProt:O76024 WFS1	3	WFS1 [endoplasmic reticulum lumen] (R-HSA-8956747) p-WFS1 [endoplasmic reticulum lumen] (R-HSA-8956998) WFS1 [endoplasmic reticulum membrane] (R-HSA-535474)	0.556	3
UniProt:P22607 FGFR3	20	FGFR3(23-760)-TACC3(612-838) fusion [plasma membrane] (R-HSA-8853144) FGFR3(23-760)-BAIAP2L1(18-522) fusion [plasma membrane] (R-HSA-8853131) FGFR3(23-793)-TACC3(143-838) fusion [plasma membrane] (R-HSA-8853152) FGFR3(23-758)-TACC3(549-838) fusion [plasma membrane] (R-HSA-8853124) FGFR3(23-758)-TACC3(649-838) fusion [plasma membrane] (R-HSA-8853125) FGFR3(23-760)-TACC3(647-838) fusion [plasma membrane] (R-HSA-8853127) FGFR3 K650T [plasma membrane] (R-HSA-1614411) FGFR3 K650N [plasma membrane] (R-HSA-1614406) FGFR3 K650M [plasma membrane] (R-HSA-1614402) FGFR3 K650Q [plasma membrane] (R-HSA-1614410) FGFR3 A391E [plasma membrane] (R-HSA-1614390) FGFR3 K650E [plasma membrane] (R-HSA-1614400) FGFR3 G380R [plasma membrane] (R-HSA-1614398) FGFR3 G382D [plasma membrane] (R-HSA-2018740) FGFR3 805fs*141 [plasma membrane] (R-HSA-1614387) FGFR3 [plasma membrane] (R-HSA-2038357) FGFR3 S371C [plasma membrane] (R-HSA-1614421) FGFR3 Y373C [plasma membrane] (R-HSA-1614424) FGFR3 G370C [plasma membrane] (R-HSA-1614394) FGFR3 R248C [plasma membrane] (R-HSA-1614419)	0.556	3
UniProt:Q7Z699 SPRED1	2	SPRED1 [plasma membrane] (R-HSA-5658225) SPRED1 [cytosol] (R-HSA-5654207)	0.556	3
UniProt:P32242 OTX1			0.556	3
UniProt:P28799 GRN	2	GRN [azurophil granule lumen] (R-HSA-6799168) GRN [extracellular region] (R-HSA-6806217)	0.556	3
UniProt:P50222 MEOX2			0.556	3
UniProt:Q15645 PCH2			0.556	3
UniProt:Q7Z398 ZNF550	1	ZNF550 [nucleoplasm] (R-HSA-1973896)	0.527	2
UniProt:P0DTD1-PRO_0000449627 REP			0.527	2
UniProt:Q8IXB1 DJC10			0.527	2
UniProt:Q9NQX6 ZNF331	1	ZNF331 [nucleoplasm] (R-HSA-1247549)	0.527	2
UniProt:Q9H0I9 TKTL2			0.527	2
UniProt:Q8N8Y5 ZFP41			0.527	2
UniProt:Q9H9D4 ZN408			0.527	2

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