HYAL1 hydrolyses (HA)50

Stable Identifier
R-HSA-2160874
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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In the acidic environment of the lysosome, hyaluronidase 1 (HYAL1) is able to hydrolyse large 20kDa HA fragments (approximately 50 disaccharide units) to 800 Da fragments (2 disaccharide units).
Literature References
PubMed ID Title Journal Year
16104017 Structures of vertebrate hyaluronidases and their unique enzymatic mechanism of hydrolysis

Jedrzejas, MJ, Stern, R

Proteins 2005
Participants
Participates
Catalyst Activity

hyalurononglucosaminidase activity of HYAL1-like proteins [lysosomal lumen]

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