Collagen type II binds integrin alpha10beta1

Stable Identifier
R-HSA-216043
Type
Reaction [binding]
Species
Homo sapiens
Compartment
extracellular region, plasma membrane
ReviewStatus
5/5
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Collagen type II binds integrin alpha10beta1
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The integrin alpha10beta1 is a collagen type II-binding integrin on chondrocytes. This integrin is of great importance during chondrogenesis. alpha10 binds the collagen-II with its I domain displaying similar binding properties as alpha1 I domain.
Literature References
PubMed ID Title Journal Year
15713743 Loss of alpha10beta1 integrin expression leads to moderate dysfunction of growth plate chondrocytes

Bengtsson, T, Lundgren-Akerlund, E, Aszodi, A, Fässler, R, Hunziker, EB, Nicolae, C

J Cell Sci 2005
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Orthologous Events
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Collagen type II binds integrin alpha10beta1 (Xenopus tropicalis)
Authored
Geiger, B  (2008-05-07)
Horwitz, AR  (2008-05-07)
Reviewed
Humphries, MJ  (2008-05-07)
Yamada, KM  (2008-05-07)
Hynes, R  (2008-05-07)
Created
Garapati, P V  (2008-03-11)
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