p-AMPK heterotrimer [nucleoplasm]

Stable Identifier
R-HSA-2151203
Type
Complex
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General

As inferred from mouse (Turnley et al. 1999) and rat (Salt et al. 1998), the alpha2 subunit of AMPK is nuclear and the alpha1 subunit is cytosolic.

Literature References
PubMed ID Title Journal Year
9693118 AMP-activated protein kinase: greater AMP dependence, and preferential nuclear localization, of complexes containing the alpha2 isoform

Prescott, A, Celler, JW, Carling, D, Hawley, SA, Woods, A, Hardie, DG, Salt, I

Biochem J 1998
10098881 Cellular distribution and developmental expression of AMP-activated protein kinase isoforms in mouse central nervous system

Bartlett, PF, Stapleton, D, Kemp, BE, Mann, RJ, Witters, LA, Turnley, AM

J Neurochem 1999
12663462 Exercise increases nuclear AMPK alpha2 in human skeletal muscle

McGee, SL, Hargreaves, M, Howlett, KF, Kemp, BE, Cameron-Smith, D, Starkie, RL

Diabetes 2003
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