Reactome | p-AMPK heterotrimer [nucleoplasm]

Stable Identifier

R-HSA-2151203

Type

Complex

Species

Homo sapiens

Compartment

nucleoplasm

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Summation

As inferred from mouse (Turnley et al. 1999) and rat (Salt et al. 1998), the alpha2 subunit of AMPK is nuclear and the alpha1 subunit is cytosolic.

Literature References

PubMed ID	Title	Journal	Year
10098881	Cellular distribution and developmental expression of AMP-activated protein kinase isoforms in mouse central nervous system	J Neurochem	1999
9693118	AMP-activated protein kinase: greater AMP dependence, and preferential nuclear localization, of complexes containing the alpha2 isoform	Biochem J	1998
12663462	Exercise increases nuclear AMPK alpha2 in human skeletal muscle	Diabetes	2003

Participants

components

Participant Of

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