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HPGDS [cytosol]
Stable Identifier
R-HSA-2142706
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Hematopoietic prostaglandin D synthase, HPGDS_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Biological oxidations (Homo sapiens)
Phase II - Conjugation of compounds (Homo sapiens)
Glutathione conjugation (Homo sapiens)
GST dimers conjugate GSH with cytosolic substrates (Homo sapiens)
GST dimers [cytosol] (Homo sapiens)
HPGDS dimer [cytosol] (Homo sapiens)
HPGDS [cytosol] (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Fatty acid metabolism (Homo sapiens)
Arachidonate metabolism (Homo sapiens)
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) (Homo sapiens)
PGH2 is isomerised to PGD2 by HPGDS (Homo sapiens)
HPGDS dimer [cytosol] (Homo sapiens)
HPGDS [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:O60760 HPGDS
Gene Names
HPGDS, GSTS, PGDS, PTGDS2
Chain
chain:1-199
Reference Genes
BioGPS Gene:27306 HPGDS
COSMIC (genes):HPGDS HPGDS
CTD Gene:27306 HPGDS
dbSNP Gene:27306 HPGDS
ENSEMBL:ENSG00000163106 HPGDS
HGNC:17890 HPGDS
KEGG:hsa:27306 HPGDS
Monarch:27306 HPGDS
NCBI Gene:27306 HPGDS
OMIM:602598 HPGDS
UCSC:O60760 HPGDS
Reference Transcript
RefSeq:NM_014485.2 HPGDS
Other Identifiers
11731633_at
11731634_at
16978036
206726_PM_at
206726_at
27306
2778274
2778275
2778276
2778278
2778279
2778280
2778281
2778282
2778283
2778285
35523_at
8101780
A_23_P10506
GE57320
GO:0000287
GO:0001516
GO:0003824
GO:0004364
GO:0004667
GO:0005509
GO:0005515
GO:0005654
GO:0005737
GO:0005829
GO:0006575
GO:0006629
GO:0006693
GO:0006749
GO:0006790
GO:0007165
GO:0007626
GO:0016740
GO:0016853
GO:0042803
GO:0043226
GO:0043231
GO:0046872
GO:2000255
HMNXSV003037010
ILMN_1713753
PH_hs_0007430
TC04001393.hg
g7657456_3p_at
Participates
as a component of
HPGDS dimer [cytosol] (Homo sapiens)
HPGDS dimer [cytosol] (Homo sapiens)
Inferred To
H-PGDS [cytosol]
(Canis familiaris)
gst-11 [cytosol]
(Caenorhabditis elegans)
hpgds [cytosol]
(Xenopus tropicalis)
HPGDS [cytosol]
(Bos taurus)
HPGDS [cytosol]
(Dictyostelium discoideum)
HPGDS [cytosol]
(Drosophila melanogaster)
HPGDS [cytosol]
(Gallus gallus)
HPGDS [cytosol]
(Mus musculus)
HPGDS [cytosol]
(Plasmodium falciparum)
HPGDS [cytosol]
(Rattus norvegicus)
HPGDS [cytosol]
(Sus scrofa)
Cross References
Guide to Pharmacology - Targets
1381
OpenTargets
ENSG00000163106
ENSEMBL
ENSP00000295256
,
ENST00000295256
,
ENSG00000163106
ZINC - Substances
HPGDS_HUMAN
ZINC target
O60760
PRO
O60760
GlyGen
O60760
PDB
2VCQ
,
1IYI
,
5YWE
,
6ZTC
,
7JR8
,
2VCZ
,
5AIX
,
3VI5
,
4EE0
,
5YX1
,
6W58
,
2CVD
,
3EE2
,
1IYH
,
2VCW
,
5AIV
,
2VD0
,
2VCX
,
3VI7
,
2VD1
,
4EC0
,
7JR6
,
5AIS
,
5YWX
,
4EDY
,
4EDZ
,
6N4E
,
1V40
,
3KXO
,
6W8H
HPA
ENSG00000163106-HPGDS
GeneCards
HPGDS
Pharos - Targets
O60760
ZINC - Predictions - Purchasable
HPGDS_HUMAN
HMDB Protein
HMDBP01575
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q13370 PDE3B
2
p-S295-PDE3B [cytosol]
(R-HSA-162419)
PDE3B [cytosol]
(R-HSA-162348)
0.556
3
UniProt:P15018 LIF
1
LIF [extracellular region]
(R-HSA-5696436)
0.556
3
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