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HPGDS [cytosol]
Stable Identifier
R-HSA-2142706
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Hematopoietic prostaglandin D synthase, HPGDS_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Biological oxidations (Homo sapiens)
Phase II - Conjugation of compounds (Homo sapiens)
Glutathione conjugation (Homo sapiens)
GST dimers conjugate GSH with cytosolic substrates (Homo sapiens)
GST dimers [cytosol] (Homo sapiens)
HPGDS dimer [cytosol] (Homo sapiens)
HPGDS [cytosol] (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Fatty acid metabolism (Homo sapiens)
Arachidonic acid metabolism (Homo sapiens)
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) (Homo sapiens)
PGH2 is isomerised to PGD2 by HPGDS (Homo sapiens)
HPGDS dimer [cytosol] (Homo sapiens)
HPGDS [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:O60760 HPGDS
Gene Names
HPGDS, GSTS, PGDS, PTGDS2
Chain
chain:1-199
Reference Genes
BioGPS Gene:27306 HPGDS
COSMIC (genes):HPGDS HPGDS
CTD Gene:27306 HPGDS
dbSNP Gene:27306 HPGDS
ENSEMBL:ENSG00000163106 HPGDS
HGNC:17890 HPGDS
KEGG Gene (Homo sapiens):27306 HPGDS
Monarch:27306 HPGDS
NCBI Gene:27306 HPGDS
OMIM:602598 HPGDS
UCSC:O60760 HPGDS
Reference Transcript
RefSeq:NM_014485.2 HPGDS
Other Identifiers
0006590075
11731633_at
11731634_at
16978036
206726_at
27306
2778274
2778275
2778276
2778278
2778279
2778280
2778283
35523_at
8101780
A_23_P10506
GE57320
GO:0000003
GO:0000287
GO:0001516
GO:0003674
GO:0004364
GO:0004667
GO:0005509
GO:0005515
GO:0005575
GO:0005622
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0006629
GO:0006631
GO:0006633
GO:0006693
GO:0006749
GO:0006790
GO:0007165
GO:0007626
GO:0008150
GO:0008283
GO:0009058
GO:0016740
GO:0016765
GO:0016853
GO:0019371
GO:0034641
GO:0042803
GO:0043167
GO:0043226
GO:0043231
GO:0044281
GO:0046872
GO:0051186
GO:1901687
GO:2000255
ILMN_1668855
ILMN_1713753
PH_hs_0007430
TC04001393.hg
g7657456_3p_at
Participant Of
hasComponent
HPGDS dimer [cytosol]
HPGDS dimer [cytosol]
Inferred To
gsta3 [cytosol] (Dictyostelium discoideum)
Hpgds [cytosol] (Mus musculus)
Hpgds [cytosol] (Rattus norvegicus)
GST [cytosol] (Plasmodium falciparum)
gsta5 [cytosol] (Dictyostelium discoideum)
GstS1 [cytosol] (Drosophila melanogaster)
HPGDS [cytosol] (Bos taurus)
HPGDS [cytosol] (Canis familiaris)
HPGDS [cytosol] (Dictyostelium discoideum)
HPGDS [cytosol] (Plasmodium falciparum)
HPGDS [cytosol] (Sus scrofa)
HPGDS [cytosol] (Xenopus tropicalis)
gsta2-2 [cytosol] (Dictyostelium discoideum)
gsta1 [cytosol] (Dictyostelium discoideum)
gsta4 [cytosol] (Dictyostelium discoideum)
Homologues of HPGDS [cytosol] (Dictyostelium discoideum)
Homologues of HPGDS [cytosol] (Plasmodium falciparum)
gst-5 [cytosol] (Caenorhabditis elegans)
Cross References
RefSeq
NP_055300.1
OpenTargets
ENSG00000163106
GeneCards
O60760
HPA
ENSG00000163106-HPGDS
ZINC - Substances
HPGDS_HUMAN
Ensembl
ENSP00000295256
,
ENST00000295256
,
ENSG00000163106
ZINC target
O60760
PRO
O60760
ZINC - Predictions - Purchasable
HPGDS_HUMAN
HMDB Protein
HMDBP01575
PDB
4EE0
,
5AIS
,
4EDZ
,
2VCZ
,
6N4E
,
4EDY
,
2VD1
,
1V40
,
3EE2
,
2CVD
,
3KXO
,
2VD0
,
1IYI
,
4EC0
,
5YX1
,
5YWX
,
2VCW
,
1IYH
,
3VI7
,
2VCX
,
2VCQ
,
5YWE
,
5AIX
,
5AIV
,
3VI5
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P15018 LIF
1
LIF [extracellular region]
(R-HSA-5696436)
0.556
3
UniProt:Q13370 PDE3B
2
PDE3B [cytosol]
(R-HSA-162348)
p-S295-PDE3B [cytosol]
(R-HSA-162419)
0.556
3
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