Synthesis of 5-eicosatetraenoic acids

Stable Identifier
R-HSA-2142688
Type
Pathway
Species
Homo sapiens
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Synthesis of 5-eicosatetraenoic acids
Click the image above or here to open this pathway in the Pathway Browser
5-hydroperoxy-eicosatetraenoic acid (5-HpETE), 5-hydroxyeicosatetraenoic acid (5S-HETE) and 5-oxo-eicosatetraenoic acid (5-oxoETE) are formed after the initial step of Arachidonate oxidation by arachidonate 5-lipoxygenase (ALOX5) (Buczynski et al. 2009, Vance & Vance 2008).
Literature References
PubMed ID Title Journal Year
  Biochemistry of Lipids, Lipoproteins and Membranes, 5th Edition

Vance, JE, Vance, DE

  2008
19244215 Thematic Review Series: Proteomics. An integrated omics analysis of eicosanoid biology

Dumlao, DS, Buczynski, MW, Dennis, EA

J Lipid Res 2009
Participants
Events
Participates
as an event of
Event Information
Go Biological Process
lipoxygenase pathway (0019372)
Orthologous Events
Synthesis of 5-eicosatetraenoic acids (Bos taurus)
Synthesis of 5-eicosatetraenoic acids (Caenorhabditis elegans)
Synthesis of 5-eicosatetraenoic acids (Canis familiaris)
Synthesis of 5-eicosatetraenoic acids (Danio rerio)
Synthesis of 5-eicosatetraenoic acids (Dictyostelium discoideum)
Synthesis of 5-eicosatetraenoic acids (Gallus gallus)
Synthesis of 5-eicosatetraenoic acids (Mus musculus)
Synthesis of 5-eicosatetraenoic acids (Rattus norvegicus)
Synthesis of 5-eicosatetraenoic acids (Sus scrofa)
Synthesis of 5-eicosatetraenoic acids (Xenopus tropicalis)
Cross References
BioModels Database
Authored
Williams, MG  (2012-02-24)
Reviewed
Rush, MG  (2012-11-10)
Created
Williams, MG  (2012-02-24)
Cite Us!