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HLA class II histocompatibility antigen, DRB1-15 beta chain [trans-Golgi network membrane]
Stable Identifier
R-HSA-2130737
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
trans-Golgi network membrane
Synonyms
HLA class II histocompatibility antigen, DW2.2/DR2.2 beta chain, HB2G_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
MHC class II antigen presentation (Homo sapiens)
Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex (Homo sapiens)
AP-1 Clathrin coated nonameric complex [trans-Golgi network membrane] (Homo sapiens)
Nonameric complex [trans-Golgi network membrane] (Homo sapiens)
MHC II alpha/beta dimer [trans-Golgi network membrane] (Homo sapiens)
HLA II beta chain [trans-Golgi network membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DRB1-15 beta chain [trans-Golgi network membrane] (Homo sapiens)
AP-1 Complex:Arf1-GTP:Clathrin Triskelion:Nonameric complex [trans-Golgi network membrane] (Homo sapiens)
Nonameric complex [trans-Golgi network membrane] (Homo sapiens)
MHC II alpha/beta dimer [trans-Golgi network membrane] (Homo sapiens)
HLA II beta chain [trans-Golgi network membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DRB1-15 beta chain [trans-Golgi network membrane] (Homo sapiens)
TGN-lysosomal vesicle coat assembly (Homo sapiens)
AP-1 Complex:Arf1-GTP:Clathrin Triskelion:Nonameric complex [trans-Golgi network membrane] (Homo sapiens)
Nonameric complex [trans-Golgi network membrane] (Homo sapiens)
MHC II alpha/beta dimer [trans-Golgi network membrane] (Homo sapiens)
HLA II beta chain [trans-Golgi network membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DRB1-15 beta chain [trans-Golgi network membrane] (Homo sapiens)
Nonameric complex [trans-Golgi network membrane] (Homo sapiens)
MHC II alpha/beta dimer [trans-Golgi network membrane] (Homo sapiens)
HLA II beta chain [trans-Golgi network membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DRB1-15 beta chain [trans-Golgi network membrane] (Homo sapiens)
TGN-lysosome vesicle uncoating and release of nonameric complex to lysosome (Homo sapiens)
TGN-lysosome vesicle with nonameric complex [trans-Golgi network membrane] (Homo sapiens)
Nonameric complex [trans-Golgi network membrane] (Homo sapiens)
MHC II alpha/beta dimer [trans-Golgi network membrane] (Homo sapiens)
HLA II beta chain [trans-Golgi network membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DRB1-15 beta chain [trans-Golgi network membrane] (Homo sapiens)
Translocation of TGN-lysosome vesicle to lysosome (Homo sapiens)
AP-1 Clathrin coated nonameric complex [trans-Golgi network membrane] (Homo sapiens)
Nonameric complex [trans-Golgi network membrane] (Homo sapiens)
MHC II alpha/beta dimer [trans-Golgi network membrane] (Homo sapiens)
HLA II beta chain [trans-Golgi network membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DRB1-15 beta chain [trans-Golgi network membrane] (Homo sapiens)
TGN-lysosome vesicle with nonameric complex [trans-Golgi network membrane] (Homo sapiens)
Nonameric complex [trans-Golgi network membrane] (Homo sapiens)
MHC II alpha/beta dimer [trans-Golgi network membrane] (Homo sapiens)
HLA II beta chain [trans-Golgi network membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DRB1-15 beta chain [trans-Golgi network membrane] (Homo sapiens)
Transport of MHC II:Ii complex along Golgi to TGN (Homo sapiens)
Nonameric complex [trans-Golgi network membrane] (Homo sapiens)
MHC II alpha/beta dimer [trans-Golgi network membrane] (Homo sapiens)
HLA II beta chain [trans-Golgi network membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DRB1-15 beta chain [trans-Golgi network membrane] (Homo sapiens)
Transport of MHC II:Ii complex to plasma membrane (Homo sapiens)
Nonameric complex [trans-Golgi network membrane] (Homo sapiens)
MHC II alpha/beta dimer [trans-Golgi network membrane] (Homo sapiens)
HLA II beta chain [trans-Golgi network membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DRB1-15 beta chain [trans-Golgi network membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P01911 HLA-DRB1
Gene Names
HLA-DRB1, HLA-DRB2
Chain
signal peptide:1-29, chain:30-266
Reference Genes
BioGPS Gene:3123 HLA-DRB1
COSMIC (genes):HLA-DRB1 HLA-DRB1
CTD Gene:3123 HLA-DRB1
dbSNP Gene:3123 HLA-DRB1
ENSEMBL:ENSG00000196126 HLA-DRB1
HGNC:4948 HLA-DRB1
KEGG:hsa:3123 HLA-DRB1
Monarch:3123 HLA-DRB1
NCBI Gene:3123 HLA-DRB1
UCSC:P01911 HLA-DRB1
Reference Transcript
RefSeq:XM_011547738.2 HLA-DRB1
RefSeq:NM_002124.3 HLA-DRB1
RefSeq:NM_001243965.1 HLA-DRB1
Other Identifiers
11723194_x_at
11759642_x_at
17017900
204670_PM_x_at
204670_x_at
208306_3p_x_at
208306_PM_x_at
208306_x_at
209312_PM_x_at
209312_x_at
215193_PM_x_at
215193_x_at
238900_3p_at
238900_PM_at
238900_at
2950021
2950023
2950033
2950034
2950035
2950046
2950052
2950056
2950057
2950058
2950068
3123
4048251
4048256
4048258
4048264
4048272
4048279
4048280
4048281
4048282
4048283
4048284
4048285
4048288
4048289
4048290
4048292
4048294
4048296
4048297
4048308
4048309
41723_s_at
63416_s_at
66780_at
75284_f_at
8125445
8178811
8180003
GO:0000139
GO:0001772
GO:0001916
GO:0001934
GO:0002250
GO:0002376
GO:0002437
GO:0002469
GO:0002491
GO:0002503
GO:0002504
GO:0002842
GO:0002862
GO:0005198
GO:0005200
GO:0005515
GO:0005615
GO:0005764
GO:0005765
GO:0005768
GO:0005773
GO:0005783
GO:0005789
GO:0005882
GO:0005886
GO:0006355
GO:0006954
GO:0006955
GO:0006959
GO:0007010
GO:0007165
GO:0008544
GO:0009897
GO:0009986
GO:0010008
GO:0012507
GO:0016020
GO:0016045
GO:0019882
GO:0019886
GO:0023026
GO:0030154
GO:0030225
GO:0030247
GO:0030658
GO:0030666
GO:0030669
GO:0031410
GO:0031902
GO:0032395
GO:0032588
GO:0032653
GO:0032673
GO:0032689
GO:0032831
GO:0033674
GO:0035774
GO:0042088
GO:0042130
GO:0042605
GO:0042608
GO:0042609
GO:0042613
GO:0043123
GO:0043226
GO:0043382
GO:0043410
GO:0045622
GO:0045657
GO:0045893
GO:0046598
GO:0048856
GO:0050778
GO:0050852
GO:0050870
GO:0051262
GO:0060089
GO:0065003
GO:0070062
GO:0070374
GO:0098553
GO:0120281
GO:2000516
HMNXSV003026942
Hs.194490.0.S1_3p_at
Hs.194490.0.S1_3p_s_at
Hs.194490.0.S1_3p_x_at
Hs.279930.0.S2_3p_s_at
Hs.279930.1.S1_3p_x_at
ILMN_1715169
M33600_f_at
PH_hs_0034480
TC06001569.hg
TC06003602.hg
TC06004123.hg
TC6_dbb_hap3000180.hg
TC6_dbb_hap3000208.hg
TC6_ssto_hap7000164.hg
g5478215_3p_x_at
Participates
as a member of
HLA II beta chain [trans-Golgi network membrane] (Homo sapiens)
Other forms of this molecule
HLA class II histocompatibility antigen, DRB1-15 beta chain [plasma membrane]
HLA class II histocompatibility antigen, DRB1-15 beta chain [lysosomal membrane]
HLA class II histocompatibility antigen, DRB1-15 beta chain [endocytic vesicle membrane]
HLA class II histocompatibility antigen, DRB1-15 beta chain [clathrin-coated endocytic vesicle membrane]
HLA class II histocompatibility antigen, DRB1-15 beta chain [transport vesicle membrane]
HLA class II histocompatibility antigen, DRB1-15 beta chain [Golgi membrane]
HLA class II histocompatibility antigen, DRB1-15 beta chain [ER to Golgi transport vesicle membrane]
HLA class II histocompatibility antigen, DRB1-15 beta chain [lumenal side of endoplasmic reticulum membrane]
Inferred To
H2-Eb1 [trans-Golgi network membrane]
(Mus musculus)
H2-Eb2 [trans-Golgi network membrane]
(Mus musculus)
Homologues of HLA class II histocompatibility antigen, DR beta 4 chain [trans-Golgi network membrane]
(Danio rerio)
Homologues of HLA class II histocompatibility antigen, DR beta 4 chain [trans-Golgi network membrane]
(Mus musculus)
LOC100153139 [trans-Golgi network membrane]
(Sus scrofa)
zmp:0000001138 [trans-Golgi network membrane]
(Danio rerio)
b2m [trans-Golgi network membrane]
(Danio rerio)
mhc2-dab [trans-Golgi network membrane]
(Xenopus tropicalis)
BLB2 [trans-Golgi network membrane]
(Gallus gallus)
RT1-Db1 [trans-Golgi network membrane]
(Rattus norvegicus)
HLA class II histocompatibility antigen, DR beta 4 chain [trans-Golgi network membrane]
(Bos taurus)
Cross References
RefSeq
NP_001230894.1
,
XP_011546040.1
,
NP_002115.2
OpenTargets
ENSG00000196126
ENSEMBL
ENSP00000353099
,
ENST00000360004
HPA
ENSG00000196126-HLA-DRB1
PRO
P01911
Pharos - Targets
P01911
GlyGen
P01911
PDB
3T0E
,
3O6F
,
6QZD
,
6CQN
,
8VRW
,
6CPN
,
2SEB
,
4X5X
,
1SJE
,
2IAN
,
6BIZ
,
6V15
,
6V0Y
,
4AH2
,
4IS6
,
3QXD
,
4FQX
,
4I5B
,
4Y1A
,
1T5X
,
1KLU
,
1JWM
,
1HXY
,
1JWU
,
4MCZ
,
3PGD
,
2OJE
,
6CQQ
,
6QZC
,
4GBX
,
2IPK
,
1KG0
,
8TBP
,
1FYT
,
1A6A
,
1J8H
,
2IAM
,
6BIY
,
3PDO
,
5JLZ
,
5NIG
,
6BIJ
,
3L6F
,
1KLG
,
1YMM
,
1T5W
,
1BX2
,
1JWS
,
8PJG
,
6CQR
,
5LAX
,
4Y19
,
2XN9
,
5NI9
,
6NIX
,
4MD4
,
6BIR
,
6BIL
,
1D5Z
,
6V19
,
6BIV
,
6V13
,
3QXA
,
6BIN
,
6HBY
,
2G9H
,
1D6E
,
4MDI
,
4OV5
,
3S4S
,
4E41
,
4MD0
,
2WBJ
,
1R5I
,
6CQJ
,
6QZA
,
6CQL
,
1D5M
,
6CPO
,
1D5X
,
6CPL
,
1SEB
,
4MD5
,
6V18
,
4X5W
,
6V1A
,
2ICW
,
1PYW
,
4AEN
,
1DLH
,
6BIX
,
3S5L
,
1SJH
,
6R0E
,
1AQD
,
2FSE
,
4MDJ
,
1LO5
,
4MCY
,
3PGC
,
4C56
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q13370 PDE3B
2
p-S295-PDE3B [cytosol]
(R-HSA-162419)
PDE3B [cytosol]
(R-HSA-162348)
0.527
2
UniProt:Q9NZJ5 EIF2AK3
3
EIF2AK3 [endoplasmic reticulum membrane]
(R-HSA-381046)
EIF2AK3(30-144)-ALK(1058-1620) fusion [cytosol]
(R-HSA-9713456)
EIF2AK3(30-144)-p-7Y-ALK(1058-1620) fusion [cytosol]
(R-HSA-9713454)
0.527
2
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