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HLA class II histocompatibility antigen, DQ [lysosomal membrane]
Stable Identifier
R-HSA-2130681
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
lysosomal membrane
Synonyms
HB21_HUMAN, HLA-DQB
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
MHC class II antigen presentation (Homo sapiens)
Cleavage of lip22 to lip10 (Homo sapiens)
MHC II:lip10 nonamer [lysosomal membrane] (Homo sapiens)
MHC II alpha/beta dimer [lysosomal membrane] (Homo sapiens)
HLA II beta chain [lysosomal membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DQ [lysosomal membrane] (Homo sapiens)
MHC II:lip22 nonamer [lysosomal membrane] (Homo sapiens)
MHC II alpha/beta dimer [lysosomal membrane] (Homo sapiens)
HLA II beta chain [lysosomal membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DQ [lysosomal membrane] (Homo sapiens)
Disassociation of CLIP from MHC II (Homo sapiens)
MHC II:CLIP [lysosomal membrane] (Homo sapiens)
MHC II alpha/beta dimer [lysosomal membrane] (Homo sapiens)
HLA II beta chain [lysosomal membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DQ [lysosomal membrane] (Homo sapiens)
peptide free MHC II:HLA-DM [lysosomal membrane] (Homo sapiens)
MHC II alpha/beta dimer [lysosomal membrane] (Homo sapiens)
HLA II beta chain [lysosomal membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DQ [lysosomal membrane] (Homo sapiens)
Generation of CLIP from lip10 (Homo sapiens)
MHC II:CLIP [lysosomal membrane] (Homo sapiens)
MHC II alpha/beta dimer [lysosomal membrane] (Homo sapiens)
HLA II beta chain [lysosomal membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DQ [lysosomal membrane] (Homo sapiens)
MHC II:lip10 nonamer [lysosomal membrane] (Homo sapiens)
MHC II alpha/beta dimer [lysosomal membrane] (Homo sapiens)
HLA II beta chain [lysosomal membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DQ [lysosomal membrane] (Homo sapiens)
Initial proteolyis of Ii by aspartic proteases to lip22 (Homo sapiens)
MHC II:lip22 nonamer [lysosomal membrane] (Homo sapiens)
MHC II alpha/beta dimer [lysosomal membrane] (Homo sapiens)
HLA II beta chain [lysosomal membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DQ [lysosomal membrane] (Homo sapiens)
Nonameric complex [lysosomal membrane] (Homo sapiens)
MHC II alpha/beta dimer [lysosomal membrane] (Homo sapiens)
HLA II beta chain [lysosomal membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DQ [lysosomal membrane] (Homo sapiens)
Loading of antigenic peptides (Homo sapiens)
peptide free MHC II:HLA-DM [lysosomal membrane] (Homo sapiens)
MHC II alpha/beta dimer [lysosomal membrane] (Homo sapiens)
HLA II beta chain [lysosomal membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DQ [lysosomal membrane] (Homo sapiens)
peptide loaded MHC class II [lysosomal membrane] (Homo sapiens)
MHC II alpha/beta dimer [lysosomal membrane] (Homo sapiens)
HLA II beta chain [lysosomal membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DQ [lysosomal membrane] (Homo sapiens)
TGN-lysosome vesicle uncoating and release of nonameric complex to lysosome (Homo sapiens)
Nonameric complex [lysosomal membrane] (Homo sapiens)
MHC II alpha/beta dimer [lysosomal membrane] (Homo sapiens)
HLA II beta chain [lysosomal membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DQ [lysosomal membrane] (Homo sapiens)
Trafficking of nonameric complex in the endocytic pathway (Homo sapiens)
Nonameric complex [lysosomal membrane] (Homo sapiens)
MHC II alpha/beta dimer [lysosomal membrane] (Homo sapiens)
HLA II beta chain [lysosomal membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DQ [lysosomal membrane] (Homo sapiens)
Transport of antigen loaded MHC II molecules to surface (Homo sapiens)
peptide loaded MHC class II [lysosomal membrane] (Homo sapiens)
MHC II alpha/beta dimer [lysosomal membrane] (Homo sapiens)
HLA II beta chain [lysosomal membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DQ [lysosomal membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P01920 HLA-DQB1
Gene Names
HLA-DQB1, HLA-DQB
Chain
signal peptide:1-32, chain:33-261
Reference Genes
BioGPS Gene:3119 HLA-DQB1
COSMIC (genes):HLA-DQB1 HLA-DQB1
CTD Gene:3119 HLA-DQB1
dbSNP Gene:3119 HLA-DQB1
ENSEMBL_homo_sapiens_GENE:ENSG00000225824.8 HLA-DQB1
ENSEMBL_homo_sapiens_GENE:ENSG00000231286.7 HLA-DQB1
ENSEMBL_homo_sapiens_GENE:ENSG00000233209.6 HLA-DQB1
HGNC:4944 HLA-DQB1
KEGG Gene (Homo sapiens):3119 HLA-DQB1
Monarch:3119 HLA-DQB1
NCBI Gene:3119 HLA-DQB1
OMIM:604305 HLA-DQB1
UCSC:P01920 HLA-DQB1
Reference Transcript
RefSeq:NM_002123.4 HLA-DQB1
RefSeq:NM_001243962.1 HLA-DQB1
Other Identifiers
17029721
17039923
209823_PM_x_at
209823_x_at
211656_3p_x_at
211656_PM_x_at
211656_x_at
212998_PM_x_at
212998_x_at
2950077
2950078
2950079
2950081
2950086
2950088
2950095
2950096
2950097
2950098
2950138
3119
36773_f_at
36878_f_at
8178826
8180022
A_23_P8108
A_33_P3424217
GO:0000139
GO:0002250
GO:0002376
GO:0002503
GO:0002504
GO:0005515
GO:0005764
GO:0005765
GO:0005768
GO:0005773
GO:0005783
GO:0005789
GO:0005794
GO:0005886
GO:0006955
GO:0006959
GO:0007155
GO:0010008
GO:0012507
GO:0016020
GO:0019882
GO:0019886
GO:0023026
GO:0023052
GO:0030658
GO:0030666
GO:0030669
GO:0031410
GO:0031902
GO:0032395
GO:0032588
GO:0042605
GO:0042613
GO:0043226
GO:0050778
GO:0050852
GO:0050870
GO:0050896
GO:0060089
GO:0065003
GO:0098553
K02405_f_at
TC6_dbb_hap3000181.hg
TC6_mann_hap4000163.hg
TC6_mcf_hap5000170.hg
TC6_ssto_hap7000165.hg
g188178_3p_x_at
g188194_3p_s_at
Participates
as a member of
HLA II beta chain [lysosomal membrane] (Homo sapiens)
Other forms of this molecule
HLA class II histocompatibility antigen, DQ [lumenal side of endoplasmic reticulum membrane]
HLA class II histocompatibility antigen, DQ [ER to Golgi transport vesicle membrane]
HLA class II histocompatibility antigen, DQB1*0602 beta chain precursor [Golgi membrane]
HLA class II histocompatibility antigen, DQ [trans-Golgi network membrane]
HLA class II histocompatibility antigen, DQ [transport vesicle membrane]
HLA class II histocompatibility antigen, DQ [clathrin-coated endocytic vesicle membrane]
HLA class II histocompatibility antigen, DQ [endocytic vesicle membrane]
HLA class II histocompatibility antigen, DQ [plasma membrane]
Inferred To
HLA-DQB2 [lysosomal membrane]
(Canis familiaris)
b2m [lysosomal membrane]
(Danio rerio)
mhc2-dab [lysosomal membrane]
(Xenopus tropicalis)
Homologues of HLA class II histocompatibility antigen, DQ [lysosomal membrane]
(Danio rerio)
Homologues of HLA class II histocompatibility antigen, DQ [lysosomal membrane]
(Sus scrofa)
RT1-Bb [lysosomal membrane]
(Rattus norvegicus)
H2-Ab1 [lysosomal membrane]
(Mus musculus)
SLA-DQB1 [lysosomal membrane]
(Sus scrofa)
zmp:0000001138 [lysosomal membrane]
(Danio rerio)
HLA class II histocompatibility antigen, DQ [lysosomal membrane]
(Bos taurus)
HLA class II histocompatibility antigen, DQ [lysosomal membrane]
(Sus scrofa)
Cross References
RefSeq
NP_002114.3
,
NP_001230891.1
OpenTargets
ENSG00000179344
GeneCards
P01920
Ensembl
ENSP00000402865
,
ENSP00000396539
,
ENST00000419914
,
ENST00000416192
,
ENST00000399088
,
ENSP00000382038
,
ENSG00000225824
,
ENST00000413089
,
ENSG00000233209
,
ENSP00000414079
,
ENST00000424806
,
ENSG00000231286
,
ENSP00000410330
,
ENST00000422950
,
ENSP00000410107
PRO
P01920
Pharos - Targets
P01920
Orphanet
18703
PDB
2NNA
,
4OZH
,
1JK8
,
4OZG
,
1S9V
,
4OZF
,
1UVQ
,
4GG6
,
4OZI
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