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HLA class II histocompatibility antigen, DM beta chain precursor [lysosomal membrane]
Stable Identifier
R-HSA-2130673
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
lysosomal membrane
Synonyms
2DMB_HUMAN, HLA-DMB
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
MHC class II antigen presentation (Homo sapiens)
Disassociation of CLIP from MHC II (Homo sapiens)
HLA-DM/HLA-DO [lysosomal membrane] (Homo sapiens)
HLA-DM [lysosomal membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DM beta chain precursor [lysosomal membrane] (Homo sapiens)
HLA-DM:HLA-DO [lysosomal membrane] (Homo sapiens)
HLA-DM [lysosomal membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DM beta chain precursor [lysosomal membrane] (Homo sapiens)
peptide free MHC II:HLA-DM [lysosomal membrane] (Homo sapiens)
HLA-DM/HLA-DO [lysosomal membrane] (Homo sapiens)
HLA-DM [lysosomal membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DM beta chain precursor [lysosomal membrane] (Homo sapiens)
HLA-DM:HLA-DO [lysosomal membrane] (Homo sapiens)
HLA-DM [lysosomal membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DM beta chain precursor [lysosomal membrane] (Homo sapiens)
Loading of antigenic peptides (Homo sapiens)
HLA-DM/HLA-DO [lysosomal membrane] (Homo sapiens)
HLA-DM [lysosomal membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DM beta chain precursor [lysosomal membrane] (Homo sapiens)
HLA-DM:HLA-DO [lysosomal membrane] (Homo sapiens)
HLA-DM [lysosomal membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DM beta chain precursor [lysosomal membrane] (Homo sapiens)
peptide free MHC II:HLA-DM [lysosomal membrane] (Homo sapiens)
HLA-DM/HLA-DO [lysosomal membrane] (Homo sapiens)
HLA-DM [lysosomal membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DM beta chain precursor [lysosomal membrane] (Homo sapiens)
HLA-DM:HLA-DO [lysosomal membrane] (Homo sapiens)
HLA-DM [lysosomal membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DM beta chain precursor [lysosomal membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P28068 HLA-DMB
Gene Names
HLA-DMB, DMB, RING7
Chain
signal peptide:1-18, chain:19-263
Reference Genes
BioGPS Gene:3109 HLA-DMB
COSMIC (genes):HLA-DMB HLA-DMB
CTD Gene:3109 HLA-DMB
dbSNP Gene:3109 HLA-DMB
ENSEMBL:ENSG00000242574 HLA-DMB
ENSEMBL_homo_sapiens_GENE:ENSG00000226264.10 HLA-DMB
ENSEMBL_homo_sapiens_GENE:ENSG00000234154.10 HLA-DMB
ENSEMBL_homo_sapiens_GENE:ENSG00000239329.8 HLA-DMB
ENSEMBL_homo_sapiens_GENE:ENSG00000241296.8 HLA-DMB
ENSEMBL_homo_sapiens_GENE:ENSG00000241674.8 HLA-DMB
ENSEMBL_homo_sapiens_GENE:ENSG00000242092.8 HLA-DMB
ENSEMBL_homo_sapiens_GENE:ENSG00000242386.8 HLA-DMB
ENSEMBL_homo_sapiens_GENE:ENSG00000242574.9 HLA-DMB
HGNC:4935 HLA-DMB
KEGG Gene (Homo sapiens):3109 HLA-DMB
Monarch:3109 HLA-DMB
NCBI Gene:3109 HLA-DMB
OMIM:142856 HLA-DMB
UCSC:P28068 HLA-DMB
Reference Transcript
RefSeq:NM_002118.4 HLA-DMB
Other Identifiers
11746961_a_at
11746962_x_at
11754471_a_at
11754681_s_at
17017998
17037290
17042506
203932_PM_at
203932_at
2950264
2950266
2950268
2950271
2950274
2950275
2950276
3109
41609_at
8125530
8180078
A_32_P351968
GE58957
GO:0002250
GO:0002376
GO:0002399
GO:0002503
GO:0002504
GO:0005515
GO:0005764
GO:0005765
GO:0005768
GO:0005773
GO:0005886
GO:0006955
GO:0007155
GO:0010008
GO:0016020
GO:0019882
GO:0019886
GO:0023026
GO:0031410
GO:0031902
GO:0042102
GO:0042605
GO:0042613
GO:0043226
GO:0043231
GO:0050778
GO:0050870
GO:0065003
GO:2001190
HMNXSV003022591
ILMN_1761733
PH_hs_0000152
TC6_apd_hap1000117.hg
TC6_cox_hap2000232.hg
TC6_dbb_hap3000209.hg
TC6_mann_hap4000209.hg
TC6_mcf_hap5000230.hg
TC6_qbl_hap6000236.hg
TC6_ssto_hap7000219.hg
U15085_at
g4504398_3p_at
Participates
as a component of
HLA-DM [lysosomal membrane] (Homo sapiens)
Inferred To
Ghost homologue of HLA class II histocompatibility antigen, DM beta chain precursor [lysosomal membrane]
(Xenopus tropicalis)
Homologues of HLA class II histocompatibility antigen, DM beta chain precursor [lysosomal membrane]
(Danio rerio)
Homologues of HLA class II histocompatibility antigen, DM beta chain precursor [lysosomal membrane]
(Mus musculus)
DLA-DMB [lysosomal membrane]
(Canis familiaris)
HLA-DMB [lysosomal membrane]
(Bos taurus)
RT1-DMb [lysosomal membrane]
(Rattus norvegicus)
b2m [lysosomal membrane]
(Danio rerio)
SLA-DMB [lysosomal membrane]
(Sus scrofa)
H2-DMb2 [lysosomal membrane]
(Mus musculus)
H2-DMb1 [lysosomal membrane]
(Mus musculus)
zmp:0000001138 [lysosomal membrane]
(Danio rerio)
Cross References
RefSeq
NP_002109.2
OpenTargets
ENSG00000242574
HPA
ENSG00000242574-HLA-DMB
GeneCards
P28068
Ensembl
ENST00000383231
,
ENSP00000413471
,
ENSP00000408453
,
ENSP00000414817
,
ENSP00000411321
,
ENSP00000393646
,
ENST00000395312
,
ENSG00000226264
,
ENST00000412948
,
ENSP00000378723
,
ENSP00000398890
,
ENSG00000241674
,
ENST00000428420
,
ENSP00000372718
,
ENSG00000234154
,
ENST00000450897
,
ENSG00000242092
,
ENSG00000242574
,
ENSG00000242386
,
ENST00000424822
,
ENST00000440078
,
ENSG00000241296
,
ENST00000418107
,
ENSG00000239329
PRO
P28068
Pharos - Targets
P28068
PDB
1HDM
,
4FQX
,
2BC4
,
4GBX
,
4I0P
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