Reactome | HLA class II histocompatibility antigen, DM beta chain precursor [lysosomal membrane]

HLA class II histocompatibility antigen, DM beta chain precursor [lysosomal membrane]

Stable Identifier

R-HSA-2130673

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

lysosomal membrane

Synonyms

2DMB_HUMAN, HLA-DMB

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P28068 HLA-DMB

Gene Names

HLA-DMB, DMB, RING7

Chain

signal peptide:1-18, chain:19-263

Reference Genes

BioGPS Gene:3109 HLA-DMB

COSMIC (genes):HLA-DMB HLA-DMB

CTD Gene:3109 HLA-DMB

dbSNP Gene:3109 HLA-DMB

ENSEMBL:ENSG00000226264.10 HLA-DMB

ENSEMBL:ENSG00000234154.10 HLA-DMB

ENSEMBL:ENSG00000239329.8 HLA-DMB

ENSEMBL:ENSG00000241296.8 HLA-DMB

ENSEMBL:ENSG00000241674.8 HLA-DMB

ENSEMBL:ENSG00000242092.8 HLA-DMB

ENSEMBL:ENSG00000242386.8 HLA-DMB

ENSEMBL:ENSG00000242574 HLA-DMB

ENSEMBL:ENSG00000242574.9 HLA-DMB

HGNC:4935 HLA-DMB

KEGG Gene (Homo sapiens):3109 HLA-DMB

Monarch:3109 HLA-DMB

NCBI Gene:3109 HLA-DMB

OMIM:142856 HLA-DMB

UCSC:P28068 HLA-DMB

Reference Transcript

RefSeq:NM_002118.4 HLA-DMB

Other Identifiers

11746961_a_at

11746962_x_at

11754471_a_at

11754681_s_at

17017998

17037290

17042506

203932_PM_at

203932_at

2950264

2950266

2950268

2950271

2950274

2950275

2950276

3109

41609_at

8125530

8180078

A_32_P351968

GE58957

GO:0002250

GO:0002376

GO:0002399

GO:0002503

GO:0002504

GO:0005515

GO:0005764

GO:0005765

GO:0005768

GO:0005773

GO:0005886

GO:0006955

GO:0007155

GO:0010008

GO:0016020

GO:0019882

GO:0019886

GO:0023026

GO:0031410

GO:0031902

GO:0042102

GO:0042613

GO:0043226

GO:0043231

GO:0050870

GO:0065003

GO:2001190

HMNXSV003022591

ILMN_1761733

PH_hs_0000152

TC6_apd_hap1000117.hg

TC6_cox_hap2000232.hg

TC6_dbb_hap3000209.hg

TC6_mann_hap4000209.hg

TC6_mcf_hap5000230.hg

TC6_qbl_hap6000236.hg

TC6_ssto_hap7000219.hg

U15085_at

g4504398_3p_at

Participates

as a component of

HLA-DM [lysosomal membrane] (Homo sapiens)

Inferred To

Ghost homologue of HLA class II histocompatibility antigen, DM beta chain precursor [lysosomal membrane] (Rattus norvegicus)

HLA-DMB [lysosomal membrane] (Bos taurus)

LOC100495183 [lysosomal membrane] (Xenopus tropicalis)

b2m [lysosomal membrane] (Danio rerio)

SLA-DMB [lysosomal membrane] (Sus scrofa)

H2-DMb1 [lysosomal membrane] (Mus musculus)

Cross References

RefSeq

NP_002109.2

OpenTargets

ENSG00000242574

HPA

ENSG00000242574-HLA-DMB

GeneCards

P28068

Ensembl

ENST00000412948, ENSG00000234154, ENSP00000411321, ENSG00000242386, ENSP00000372718, ENSP00000413471, ENSP00000414817, ENSP00000378723, ENSP00000398890, ENSG00000242092, ENSG00000242574, ENST00000428420, ENSG00000241296, ENSP00000408453, ENSG00000241674, ENST00000383231, ENST00000395312, ENSG00000226264, ENST00000440078, ENST00000450897, ENSG00000239329, ENSP00000393646, ENST00000418107, ENST00000424822

PRO

P28068

Pharos - Targets

P28068

PDB

1HDM, 4GBX, 4I0P, 4FQX, 2BC4