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HLA class II histocompatibility antigen, DRB1-10 beta chain [trans-Golgi network membrane]
Stable Identifier
R-HSA-2130660
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
trans-Golgi network membrane
Synonyms
HLA-DRB1, 2B1A_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
MHC class II antigen presentation (Homo sapiens)
Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex (Homo sapiens)
AP-1 Clathrin coated nonameric complex [trans-Golgi network membrane] (Homo sapiens)
Nonameric complex [trans-Golgi network membrane] (Homo sapiens)
MHC II alpha/beta dimer [trans-Golgi network membrane] (Homo sapiens)
HLA II beta chain [trans-Golgi network membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DRB1-10 beta chain [trans-Golgi network membrane] (Homo sapiens)
AP-1 Complex:Arf1-GTP:Clathrin Triskelion:Nonameric complex [trans-Golgi network membrane] (Homo sapiens)
Nonameric complex [trans-Golgi network membrane] (Homo sapiens)
MHC II alpha/beta dimer [trans-Golgi network membrane] (Homo sapiens)
HLA II beta chain [trans-Golgi network membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DRB1-10 beta chain [trans-Golgi network membrane] (Homo sapiens)
TGN-lysosomal vesicle coat assembly (Homo sapiens)
AP-1 Complex:Arf1-GTP:Clathrin Triskelion:Nonameric complex [trans-Golgi network membrane] (Homo sapiens)
Nonameric complex [trans-Golgi network membrane] (Homo sapiens)
MHC II alpha/beta dimer [trans-Golgi network membrane] (Homo sapiens)
HLA II beta chain [trans-Golgi network membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DRB1-10 beta chain [trans-Golgi network membrane] (Homo sapiens)
Nonameric complex [trans-Golgi network membrane] (Homo sapiens)
MHC II alpha/beta dimer [trans-Golgi network membrane] (Homo sapiens)
HLA II beta chain [trans-Golgi network membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DRB1-10 beta chain [trans-Golgi network membrane] (Homo sapiens)
TGN-lysosome vesicle uncoating and release of nonameric complex to lysosome (Homo sapiens)
TGN-lysosome vesicle with nonameric complex [trans-Golgi network membrane] (Homo sapiens)
Nonameric complex [trans-Golgi network membrane] (Homo sapiens)
MHC II alpha/beta dimer [trans-Golgi network membrane] (Homo sapiens)
HLA II beta chain [trans-Golgi network membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DRB1-10 beta chain [trans-Golgi network membrane] (Homo sapiens)
Translocation of TGN-lysosome vesicle to lysosome (Homo sapiens)
AP-1 Clathrin coated nonameric complex [trans-Golgi network membrane] (Homo sapiens)
Nonameric complex [trans-Golgi network membrane] (Homo sapiens)
MHC II alpha/beta dimer [trans-Golgi network membrane] (Homo sapiens)
HLA II beta chain [trans-Golgi network membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DRB1-10 beta chain [trans-Golgi network membrane] (Homo sapiens)
TGN-lysosome vesicle with nonameric complex [trans-Golgi network membrane] (Homo sapiens)
Nonameric complex [trans-Golgi network membrane] (Homo sapiens)
MHC II alpha/beta dimer [trans-Golgi network membrane] (Homo sapiens)
HLA II beta chain [trans-Golgi network membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DRB1-10 beta chain [trans-Golgi network membrane] (Homo sapiens)
Transport of MHC II:Ii complex along Golgi to TGN (Homo sapiens)
Nonameric complex [trans-Golgi network membrane] (Homo sapiens)
MHC II alpha/beta dimer [trans-Golgi network membrane] (Homo sapiens)
HLA II beta chain [trans-Golgi network membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DRB1-10 beta chain [trans-Golgi network membrane] (Homo sapiens)
Transport of MHC II:Ii complex to plasma membrane (Homo sapiens)
Nonameric complex [trans-Golgi network membrane] (Homo sapiens)
MHC II alpha/beta dimer [trans-Golgi network membrane] (Homo sapiens)
HLA II beta chain [trans-Golgi network membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DRB1-10 beta chain [trans-Golgi network membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q30167 HLA-DRB1
Gene Names
HLA-DRB1
Chain
signal peptide:1-29, chain:30-266
Reference Genes
BioGPS Gene:3123 HLA-DRB1
COSMIC (genes):HLA-DRB1 HLA-DRB1
CTD Gene:3123 HLA-DRB1
dbSNP Gene:3123 HLA-DRB1
ENSEMBL:ENSG00000196126 HLA-DRB1
ENSEMBL:ENSG00000228080 HLA-DRB1
KEGG Gene (Homo sapiens):3123 HLA-DRB1
Monarch:3123 HLA-DRB1
NCBI Gene:3123 HLA-DRB1
UCSC:Q30167 HLA-DRB1
Reference Transcript
RefSeq:XM_011547738.2 HLA-DRB1
RefSeq:NM_002124.3 HLA-DRB1
RefSeq:NM_001243965.1 HLA-DRB1
Participates
as a member of
HLA II beta chain [trans-Golgi network membrane] (Homo sapiens)
Other forms of this molecule
HLA class II histocompatibility antigen, DRB1-10 beta chain [integral component of lumenal side of endoplasmic reticulum membrane]
HLA class II histocompatibility antigen, DRB1-10 beta chain [ER to Golgi transport vesicle membrane]
HLA class II histocompatibility antigen, DRB1-10 beta chain [Golgi membrane]
HLA class II histocompatibility antigen, DRB1-10 beta chain [transport vesicle membrane]
HLA class II histocompatibility antigen, DRB1-10 beta chain [clathrin-coated endocytic vesicle membrane]
HLA class II histocompatibility antigen, DRB1-10 beta chain [endocytic vesicle membrane]
HLA class II histocompatibility antigen, DRB1-10 beta chain [lysosomal membrane]
HLA class II histocompatibility antigen, DRB1-10 beta chain [plasma membrane]
Cross References
RefSeq
XP_011546040.1
,
NP_001230894.1
,
NP_002115.2
OpenTargets
ENSG00000196126
GeneCards
Q30167
PRO
Q30167
Pharos - Targets
Q30167
PDB
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,
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