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HLA class II histocompatibility antigen, DRB1-9 beta chain precursor [integral component of lumenal side of endoplasmic reticulum membrane]
Stable Identifier
R-HSA-2130571
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
integral component of lumenal side of endoplasmic reticulum membrane
Synonyms
2B19_HUMAN, HLA-DRB1
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
MHC class II antigen presentation (Homo sapiens)
Dissociation of CANX from nonameric complex (Homo sapiens)
2xMHC II alpha beta heterodimer:alpha beta dimer:Ii trimer [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
MHC II alpha beta heterodimer [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA II beta chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DRB1-9 beta chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
alpha beta dimer:Ii trimer [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
MHC II alpha beta heterodimer [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA II beta chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DRB1-9 beta chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
2xMHC II alpha beta heterodimer:alpha beta dimer:Ii trimer:calnexin [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
MHC II alpha beta heterodimer [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA II beta chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DRB1-9 beta chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
alpha beta dimer:Ii trimer:calnexin [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
MHC II alpha beta heterodimer [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA II beta chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DRB1-9 beta chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Formation of COPII vesicle (Homo sapiens)
Nonameric complex [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
MHC II alpha beta heterodimer [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA II beta chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DRB1-9 beta chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Formation of MHC II alpha beta heterodimer (Homo sapiens)
HLA II beta chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DRB1-9 beta chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
MHC II alpha beta heterodimer [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA II beta chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DRB1-9 beta chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Formation of nonameric complex (Homo sapiens)
2xMHC II alpha beta heterodimer:alpha beta dimer:Ii trimer:calnexin [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
MHC II alpha beta heterodimer [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA II beta chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DRB1-9 beta chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
alpha beta dimer:Ii trimer:calnexin [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
MHC II alpha beta heterodimer [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA II beta chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DRB1-9 beta chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
MHC II alpha beta heterodimer [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA II beta chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DRB1-9 beta chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
alpha beta dimer:Ii trimer:calnexin [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
MHC II alpha beta heterodimer [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA II beta chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DRB1-9 beta chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Interaction of invariant chain trimer and MHC II alpha beta dimer (Homo sapiens)
MHC II alpha beta heterodimer [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA II beta chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DRB1-9 beta chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
alpha beta dimer:Ii trimer:calnexin [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
MHC II alpha beta heterodimer [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA II beta chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DRB1-9 beta chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9TQE0 HLA-DRB1
Gene Names
HLA-DRB1
Chain
signal peptide:1-29, chain:30-266
Reference Genes
BioGPS Gene:3123 HLA-DRB1
COSMIC (genes):HLA-DRB1 HLA-DRB1
CTD Gene:3123 HLA-DRB1
dbSNP Gene:3123 HLA-DRB1
ENSEMBL:ENSG00000196126 HLA-DRB1
KEGG Gene (Homo sapiens):3123 HLA-DRB1
Monarch:3123 HLA-DRB1
NCBI Gene:3123 HLA-DRB1
UCSC:Q9TQE0 HLA-DRB1
Reference Transcript
RefSeq:NM_002124.3 HLA-DRB1
RefSeq:XM_011547738.2 HLA-DRB1
RefSeq:NM_001243965.1 HLA-DRB1
Participates
as a member of
HLA II beta chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Other forms of this molecule
HLA class II histocompatibility antigen, DRB1-9 beta chain precursor [ER to Golgi transport vesicle membrane]
HLA class II histocompatibility antigen, DRB1-9 beta chain precursor [Golgi membrane]
HLA class II histocompatibility antigen, DRB1-9 beta chain precursor [trans-Golgi network membrane]
HLA class II histocompatibility antigen, DRB1-9 beta chain precursor [transport vesicle membrane]
HLA class II histocompatibility antigen, DRB1-9 beta chain precursor [clathrin-coated endocytic vesicle membrane]
HLA class II histocompatibility antigen, DRB1-9 beta chain precursor [endocytic vesicle membrane]
HLA class II histocompatibility antigen, DRB1-9 beta chain precursor [lysosomal membrane]
HLA class II histocompatibility antigen, DRB1-9 beta chain precursor [plasma membrane]
Cross References
RefSeq
NP_002115.2
,
XP_011546040.1
,
NP_001230894.1
OpenTargets
ENSG00000196126
GeneCards
Q9TQE0
PRO
Q9TQE0
Pharos - Targets
Q9TQE0
PDB
1LO5
,
6CQL
,
6CQN
,
1JWU
,
1KG0
,
6V18
,
6BIX
,
3S4S
,
2IAN
,
1SEB
,
3QXA
,
6BIV
,
6QZC
,
2G9H
,
6HBY
,
4MD4
,
5NI9
,
4MCZ
,
6CPO
,
6BIN
,
1T5W
,
4MCY
,
4MD0
,
1D6E
,
1HXY
,
1SJH
,
6BIJ
,
1YMM
,
6V15
,
4MDI
,
1AQD
,
2SEB
,
1D5X
,
3T0E
,
5NIG
,
1JWM
,
6V19
,
4MD5
,
1KLG
,
6CQR
,
2IAM
,
3PGD
,
4C56
,
4IS6
,
4AEN
,
1SJE
,
3O6F
,
5JLZ
,
1BX2
,
2OJE
,
1D5Z
,
2ICW
,
6QZA
,
4OV5
,
1J8H
,
4GBX
,
3PGC
,
4Y1A
,
6V1A
,
4AH2
,
6V13
,
3PDO
,
6CPL
,
4Y19
,
3S5L
,
2XN9
,
3L6F
,
1JWS
,
1KLU
,
1R5I
,
4I5B
,
1DLH
,
4E41
,
2IPK
,
6BIZ
,
5LAX
,
6NIX
,
6CQJ
,
6BIY
,
3QXD
,
6CQQ
,
4FQX
,
1FYT
,
6R0E
,
2WBJ
,
1D5M
,
1A6A
,
6BIR
,
4X5X
,
1T5X
,
6QZD
,
1PYW
,
4X5W
,
6CPN
,
6BIL
,
6V0Y
,
2FSE
,
4MDJ
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