Reactome | AP1S1 [trans-Golgi network membrane]

AP1S1 [trans-Golgi network membrane]

Stable Identifier

R-HSA-2130566

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

trans-Golgi network membrane

Synonyms

AP-1 sigma 1A

Locations in the PathwayBrowser

Expand all

Vesicle-mediated transport (Homo sapiens)

- Membrane Trafficking (Homo sapiens)
  - trans-Golgi Network Vesicle Budding (Homo sapiens)
    - Lysosome Vesicle Biogenesis (Homo sapiens)
      - CLAT:AP1:CLVS bind PI(3,5)P2 (Homo sapiens)
        
        CLAT:AP1:CLVS [trans-Golgi network membrane] (Homo sapiens)
        
        AP1 complex [trans-Golgi network membrane] (Homo sapiens)
        
        AP1S1,2,3 [trans-Golgi network membrane] (Homo sapiens)
        
        AP1S1 [trans-Golgi network membrane] (Homo sapiens)
        
        CLAT:AP1:CLVS:PI(3,5)P2 [clathrin-coated endocytic vesicle] (Homo sapiens)
        
        CLAT:AP1:CLVS [trans-Golgi network membrane] (Homo sapiens)
        
        AP1 complex [trans-Golgi network membrane] (Homo sapiens)
        
        AP1S1,2,3 [trans-Golgi network membrane] (Homo sapiens)
        
        AP1S1 [trans-Golgi network membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:P61966 AP1S1

Gene Names

AP1S1, AP19, CLAPS1

Chain

chain:1-158

Reference Genes

BioGPS Gene:1174 AP1S1

COSMIC (genes):AP1S1 AP1S1

CTD Gene:1174 AP1S1

dbSNP Gene:1174 AP1S1

ENSEMBL:ENSG00000106367 AP1S1

ENSEMBL_homo_sapiens_GENE:ENSG00000106367.15 AP1S1

HGNC:559 AP1S1

KEGG Gene (Homo sapiens):1174 AP1S1

Monarch:1174 AP1S1

NCBI Gene:1174 AP1S1

OMIM:603531 AP1S1

UCSC:P61966 AP1S1

Reference Transcript

RefSeq:NM_001283.3 AP1S1

Other Identifiers

11721476_a_at

1174

11745357_x_at

17049692

205195_PM_at

205195_at

205196_PM_s_at

205196_s_at

209635_PM_at

209635_at

3016178

3016181

3016182

3016183

3016184

3016187

3016188

3016189

3016190

3016191

3016192

3016193

36498_at

72897_at

8135080

A_23_P157404

A_24_P63950

GE53409

GO:0000139

GO:0005764

GO:0005765

GO:0005768

GO:0005769

GO:0005773

GO:0005794

GO:0005829

GO:0005886

GO:0005905

GO:0006886

GO:0006898

GO:0009615

GO:0015031

GO:0016020

GO:0016192

GO:0030117

GO:0030121

GO:0030659

GO:0031410

GO:0032588

GO:0035615

GO:0043226

GO:0043231

GO:0060090

GO:0060155

GO:0110010

GO:1903232

HMNXSV003053419

ILMN_1712806

ILMN_1751345

ILMN_2316173

PH_hs_0025102

TC07000644.hg

g13097710_3p_at

g4557470_3p_a_at

g4557470_3p_x_at

Participates

as a member of

AP1S1,2,3 [trans-Golgi network membrane] (Homo sapiens)

Other forms of this molecule

AP1S1 [cytoplasmic vesicle membrane]

AP1S1 [Golgi membrane]

AP1S1 [lysosomal membrane]

AP1S1 [cytosol]

Inferred To

AP-1sigma [trans-Golgi network membrane] (Drosophila melanogaster)

Homologues of AP1S1 [trans-Golgi network membrane] (Dictyostelium discoideum)

vas2 [trans-Golgi network membrane] (Schizosaccharomyces pombe)

APS1 [trans-Golgi network membrane] (Saccharomyces cerevisiae)

ap1s1 [trans-Golgi network membrane] (Danio rerio)

ap1s1 [trans-Golgi network membrane] (Dictyostelium discoideum)

ap1s1 [trans-Golgi network membrane] (Xenopus tropicalis)

ap1s2 [trans-Golgi network membrane] (Dictyostelium discoideum)

aps-1 [trans-Golgi network membrane] (Caenorhabditis elegans)

AP1S1 [trans-Golgi network membrane] (Bos taurus)

AP1S1 [trans-Golgi network membrane] (Canis familiaris)

AP1S1 [trans-Golgi network membrane] (Sus scrofa)

Ap1s1 [trans-Golgi network membrane] (Mus musculus)

Ap1s1 [trans-Golgi network membrane] (Rattus norvegicus)

Cross References

RefSeq

NP_001274.1

OpenTargets

ENSG00000106367

GeneCards

P61966

HPA

ENSG00000106367-AP1S1

Ensembl

ENST00000337619, ENST00000443943, ENSP00000336666, ENSP00000410780, ENSG00000106367

PRO

P61966

Pharos - Targets

P61966

Orphanet

18005

PDB

4P6Z