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HLA class II histocompatibility antigen, DRB3-1 beta chain precursor [transport vesicle membrane]
Stable Identifier
R-HSA-2130559
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
transport vesicle membrane
Synonyms
2B31_HUMAN, HLA-DRB3
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
MHC class II antigen presentation (Homo sapiens)
Insertion of MHC II:Ii complex in to the plasma membrane (Homo sapiens)
MHC class II alpha/beta/Ii nonamer [transport vesicle membrane] (Homo sapiens)
HLA II beta chain [transport vesicle membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DRB3-1 beta chain precursor [transport vesicle membrane] (Homo sapiens)
Transport of MHC II:Ii complex to plasma membrane (Homo sapiens)
MHC class II alpha/beta/Ii nonamer [transport vesicle membrane] (Homo sapiens)
HLA II beta chain [transport vesicle membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DRB3-1 beta chain precursor [transport vesicle membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P79483 HLA-DRB3
Gene Names
HLA-DRB3
Chain
signal peptide:1-29, chain:30-266
Reference Genes
BioGPS Gene:3125 HLA-DRB3
CTD Gene:3125 HLA-DRB3
dbSNP Gene:3125 HLA-DRB3
ENSEMBL:ENSG00000196101 HLA-DRB3
ENSEMBL_homo_sapiens_GENE:ENSG00000196101.10 HLA-DRB3
ENSEMBL_homo_sapiens_GENE:ENSG00000231679.8 HLA-DRB3
HGNC:4951 HLA-DRB3
KEGG Gene (Homo sapiens):3125 HLA-DRB3
Monarch:3125 HLA-DRB3
NCBI Gene:3125 HLA-DRB3
OMIM:612735 HLA-DRB3
UCSC:P79483 HLA-DRB3
Reference Transcript
RefSeq:NM_022555.3 HLA-DRB3
Other Identifiers
11723194_x_at
11759642_x_at
17027082
17029705
17039907
215193_PM_x_at
215193_x_at
2950021
2950023
2950025
2950027
2950032
2950033
2950035
2950052
2950057
2950060
3125
4048258
4048272
4048275
4048282
4048284
41723_s_at
8178802
8178811
8180003
A_23_P145336
A_24_P402222
GE532983
GO:0000139
GO:0002250
GO:0002376
GO:0002469
GO:0002503
GO:0002504
GO:0002842
GO:0005515
GO:0005764
GO:0005765
GO:0005768
GO:0005773
GO:0005783
GO:0005789
GO:0005794
GO:0005886
GO:0006955
GO:0007155
GO:0007165
GO:0010008
GO:0012507
GO:0016020
GO:0019882
GO:0019886
GO:0023026
GO:0023052
GO:0030658
GO:0030666
GO:0030669
GO:0031410
GO:0031902
GO:0032395
GO:0032588
GO:0042605
GO:0042613
GO:0043226
GO:0050778
GO:0050852
GO:0050870
GO:0060089
GO:0065003
GO:0098553
GO:0120281
GO:2000516
HMNXSV003044723
Hs.279930.1.S1_3p_x_at
ILMN_1717261
TC6_apd_hap1000101.hg
TC6_dbb_hap3000208.hg
TC6_ssto_hap7000164.hg
Participates
as a member of
HLA II beta chain [transport vesicle membrane] (Homo sapiens)
Other forms of this molecule
HLA class II histocompatibility antigen, DRB3-1 beta chain precursor [lumenal side of endoplasmic reticulum membrane]
HLA class II histocompatibility antigen, DRB3-1 beta chain precursor [ER to Golgi transport vesicle membrane]
HLA class II histocompatibility antigen, DRB3-1 beta chain precursor [Golgi membrane]
HLA class II histocompatibility antigen, DRB3-1 beta chain precursor [trans-Golgi network membrane]
HLA class II histocompatibility antigen, DRB3-1 beta chain precursor [clathrin-coated endocytic vesicle membrane]
HLA class II histocompatibility antigen, DRB3-1 beta chain precursor [endocytic vesicle membrane]
HLA class II histocompatibility antigen, DRB3-1 beta chain precursor [lysosomal membrane]
HLA class II histocompatibility antigen, DRB3-1 beta chain precursor [plasma membrane]
Inferred To
Homologues of HLA class II histocompatibility antigen, DR beta 4 chain [transport vesicle membrane]
(Danio rerio)
Homologues of HLA class II histocompatibility antigen, DR beta 4 chain [transport vesicle membrane]
(Mus musculus)
BOLA-DRB3 [transport vesicle membrane]
(Bos taurus)
H2-Eb1 [transport vesicle membrane]
(Mus musculus)
H2-Eb2 [transport vesicle membrane]
(Mus musculus)
LOC100153139 [transport vesicle membrane]
(Sus scrofa)
b2m [transport vesicle membrane]
(Danio rerio)
zmp:0000001138 [transport vesicle membrane]
(Danio rerio)
RT1-Db1 [transport vesicle membrane]
(Rattus norvegicus)
Cross References
RefSeq
NP_072049.2
GeneCards
P79483
ZINC - Substances
DRB3_HUMAN
Ensembl
ENSG00000231679
,
ENSP00000372607
,
ENST00000383126
,
ENST00000307137
,
ENSG00000196101
,
ENSP00000302517
ZINC target
P79483
PRO
P79483
Pharos - Targets
P79483
ZINC - Predictions - Purchasable
DRB3_HUMAN
PDB
3C5J
,
4H1L
,
2Q6W
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P36957 DLST
5
Lipo-K110-DLST [mitochondrial matrix]
(R-HSA-69993)
SuccinyllipoH2-K110-DLST [mitochondrial matrix]
(R-HSA-9853502)
LipoH2-K110-DLST [mitochondrial matrix]
(R-HSA-9853485)
DLST [mitochondrial matrix]
(R-HSA-6792574)
GlutaryllipoH2-K110-DLST [mitochondrial matrix]
(R-HSA-9858581)
0.556
3
UniProt:P27797 CALR
6
CALR [lumenal side of endoplasmic reticulum membrane]
(R-HSA-985502)
CALR [endoplasmic reticulum lumen]
(R-HSA-195905)
CALR [extracellular region]
(R-HSA-2197641)
CALR [endocytic vesicle lumen]
(R-HSA-2239448)
CALR [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-8863866)
CALR [phagocytic vesicle membrane]
(R-HSA-1236879)
0.556
3
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