Insertion of MHC II:Ii complex in to the plasma membrane

Stable Identifier
R-HSA-2130500
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
plasma membrane, transport vesicle membrane
ReviewStatus
5/5
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Insertion of MHC II:Ii complex in to the plasma membrane
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On reaching the cell surface, transport carrier vesicles insert the cargo MHC II:Ii complex into the plasma membrane.

Literature References
PubMed ID Title Journal Year
8397411 Cell surface HLA-DR-invariant chain complexes are targeted to endosomes by rapid internalization

Teletski, CL, Roche, PA, Long, EO, Stang, E, Bakke, O

Proc Natl Acad Sci U S A 1993
10540230 Cell surface expression and metabolism of major histocompatibility complex class II invariant chain (CD74) by diverse cell lines

Mattes, MJ, Goldenberg, DM, Hansen, HJ, Ong, GL

Immunology 1999
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Output
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as an event of
Orthologous Events
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Insertion of MHC II:Ii complex in to the plasma membrane (Mus musculus)
Insertion of MHC II:Ii complex in to the plasma membrane (Rattus norvegicus)
Insertion of MHC II:Ii complex in to the plasma membrane (Sus scrofa)
Authored
Garapati, P V  (2012-02-21)
Reviewed
Neefjes, J  (2012-05-14)
Created
Garapati, P V  (2012-02-21)
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