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HLA class II histocompatibility antigen, DQ beta 2 chain [integral component of lumenal side of endoplasmic reticulum membrane]
Stable Identifier
R-HSA-2130458
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
integral component of lumenal side of endoplasmic reticulum membrane
Synonyms
HLA class II histocompatibility antigen, DX beta chain precursor, HB2X_HUMAN, HLA-DQB2
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
MHC class II antigen presentation (Homo sapiens)
Dissociation of CANX from nonameric complex (Homo sapiens)
2xMHC II alpha beta heterodimer:alpha beta dimer:Ii trimer [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
MHC II alpha beta heterodimer [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA II beta chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DQ beta 2 chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
alpha beta dimer:Ii trimer [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
MHC II alpha beta heterodimer [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA II beta chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DQ beta 2 chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
2xMHC II alpha beta heterodimer:alpha beta dimer:Ii trimer:calnexin [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
MHC II alpha beta heterodimer [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA II beta chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DQ beta 2 chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
alpha beta dimer:Ii trimer:calnexin [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
MHC II alpha beta heterodimer [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA II beta chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DQ beta 2 chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Formation of COPII vesicle (Homo sapiens)
Nonameric complex [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
MHC II alpha beta heterodimer [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA II beta chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DQ beta 2 chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Formation of MHC II alpha beta heterodimer (Homo sapiens)
HLA II beta chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DQ beta 2 chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
MHC II alpha beta heterodimer [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA II beta chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DQ beta 2 chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Formation of nonameric complex (Homo sapiens)
2xMHC II alpha beta heterodimer:alpha beta dimer:Ii trimer:calnexin [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
MHC II alpha beta heterodimer [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA II beta chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DQ beta 2 chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
alpha beta dimer:Ii trimer:calnexin [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
MHC II alpha beta heterodimer [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA II beta chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DQ beta 2 chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
MHC II alpha beta heterodimer [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA II beta chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DQ beta 2 chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
alpha beta dimer:Ii trimer:calnexin [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
MHC II alpha beta heterodimer [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA II beta chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DQ beta 2 chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Interaction of invariant chain trimer and MHC II alpha beta dimer (Homo sapiens)
MHC II alpha beta heterodimer [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA II beta chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DQ beta 2 chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
alpha beta dimer:Ii trimer:calnexin [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
MHC II alpha beta heterodimer [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA II beta chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DQ beta 2 chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P05538 HLA-DQB2
Gene Names
HLA-DQB2, HLA-DXB
Chain
signal peptide:1-32, chain:33-268
Reference Genes
BioGPS Gene:3120 HLA-DQB2
COSMIC (genes):HLA-DQB2 HLA-DQB2
CTD Gene:3120 HLA-DQB2
dbSNP Gene:3120 HLA-DQB2
ENSEMBL:ENSG00000196610.13 HLA-DQB2
ENSEMBL:ENSG00000224305.9 HLA-DQB2
ENSEMBL:ENSG00000226165.9 HLA-DQB2
ENSEMBL:ENSG00000228254.9 HLA-DQB2
ENSEMBL:ENSG00000228813.9 HLA-DQB2
ENSEMBL:ENSG00000229493.9 HLA-DQB2
ENSEMBL:ENSG00000230675.9 HLA-DQB2
ENSEMBL:ENSG00000232629 HLA-DQB2
ENSEMBL:ENSG00000232629.9 HLA-DQB2
HGNC:4945 HLA-DQB2
KEGG Gene (Homo sapiens):3120 HLA-DQB2
Monarch:3120 HLA-DQB2
NCBI Gene:3120 HLA-DQB2
OMIM:615161 HLA-DQB2
UCSC:P05538 HLA-DQB2
Reference Transcript
RefSeq:NM_001198858.1 HLA-DQB2
Other Identifiers
17017926
17027091
17029735
17032423
17034749
17037218
17039935
17042433
215536_PM_at
215536_at
2950086
2950088
2950103
2950126
2950127
2950128
2950130
2950133
2950134
2950138
3120
8125463
8178826
8180022
8180029
A_23_P19510
GE87723
GO:0000139
GO:0002250
GO:0002376
GO:0002503
GO:0002504
GO:0005764
GO:0005765
GO:0005768
GO:0005773
GO:0005783
GO:0005789
GO:0005794
GO:0005886
GO:0006955
GO:0007155
GO:0010008
GO:0012507
GO:0016020
GO:0019882
GO:0019886
GO:0023026
GO:0030658
GO:0030666
GO:0030669
GO:0031410
GO:0032395
GO:0032588
GO:0042613
GO:0043226
GO:0050870
GO:0060089
GO:0065003
GO:0098553
HMNXSV003051220
Hs.247964.0.S1_3p_at
Hs.73931.3.A1_3p_x_at
ILMN_1741648
TC06001571.hg
TC6_apd_hap1000102.hg
TC6_cox_hap2000196.hg
TC6_dbb_hap3000182.hg
TC6_mann_hap4000164.hg
TC6_mcf_hap5000171.hg
TC6_qbl_hap6000184.hg
TC6_ssto_hap7000166.hg
X87344_cds10_r_at
Participates
as a member of
HLA II beta chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Other forms of this molecule
HLA class II histocompatibility antigen, DQ beta 2 chain [ER to Golgi transport vesicle membrane]
HLA class II histocompatibility antigen, DQ beta 2 chain [Golgi membrane]
HLA class II histocompatibility antigen, DQ beta 2 chain [trans-Golgi network membrane]
HLA class II histocompatibility antigen, DQ beta 2 chain [transport vesicle membrane]
HLA class II histocompatibility antigen, DQ beta 2 chain [clathrin-coated endocytic vesicle membrane]
HLA class II histocompatibility antigen, DQ beta 2 chain [endocytic vesicle membrane]
HLA class II histocompatibility antigen, DQ beta 2 chain [lysosomal membrane]
HLA class II histocompatibility antigen, DQ beta 2 chain [plasma membrane]
Inferred To
Homologues of HLA class II histocompatibility antigen, DQ beta 2 chain [integral component of lumenal side of endoplasmic reticulum membrane]
(Bos taurus)
Homologues of HLA class II histocompatibility antigen, DQ beta 2 chain [integral component of lumenal side of endoplasmic reticulum membrane]
(Canis familiaris)
Homologues of HLA class II histocompatibility antigen, DQ beta 2 chain [integral component of lumenal side of endoplasmic reticulum membrane]
(Danio rerio)
Homologues of HLA class II histocompatibility antigen, DQ beta 2 chain [integral component of lumenal side of endoplasmic reticulum membrane]
(Gallus gallus)
si:busm1-104n07.3 [integral component of lumenal side of endoplasmic reticulum membrane]
(Danio rerio)
BoLA-DIB [integral component of lumenal side of endoplasmic reticulum membrane]
(Bos taurus)
LOC103911540 [integral component of lumenal side of endoplasmic reticulum membrane]
(Danio rerio)
hla-drb1 [integral component of lumenal side of endoplasmic reticulum membrane]
(Xenopus tropicalis)
si:ch73-158p21.3 [integral component of lumenal side of endoplasmic reticulum membrane]
(Danio rerio)
si:busm1-228j01.6 [integral component of lumenal side of endoplasmic reticulum membrane]
(Danio rerio)
si:zfos-2070c2.3 [integral component of lumenal side of endoplasmic reticulum membrane]
(Danio rerio)
SLA-DQB1 [integral component of lumenal side of endoplasmic reticulum membrane]
(Sus scrofa)
si:busm1-160c18.3 [integral component of lumenal side of endoplasmic reticulum membrane]
(Danio rerio)
BOLA-DQB [integral component of lumenal side of endoplasmic reticulum membrane]
(Bos taurus)
H2-Ab1 [integral component of lumenal side of endoplasmic reticulum membrane]
(Mus musculus)
BLA-DQB [integral component of lumenal side of endoplasmic reticulum membrane]
(Bos taurus)
BLB2 [integral component of lumenal side of endoplasmic reticulum membrane]
(Gallus gallus)
RT1-Bb [integral component of lumenal side of endoplasmic reticulum membrane]
(Rattus norvegicus)
BLB1 [integral component of lumenal side of endoplasmic reticulum membrane]
(Gallus gallus)
HLA class II histocompatibility antigen, DQ beta 2 chain [integral component of lumenal side of endoplasmic reticulum membrane]
(Canis familiaris)
HLA class II histocompatibility antigen, DQ beta 2 chain [integral component of lumenal side of endoplasmic reticulum membrane]
(Danio rerio)
HLA class II histocompatibility antigen, DQ beta 2 chain [integral component of lumenal side of endoplasmic reticulum membrane]
(Gallus gallus)
Cross References
RefSeq
NP_001185787.1
OpenTargets
ENSG00000232629
HPA
ENSG00000232629-HLA-DQB2
GeneCards
P05538
Ensembl
ENSP00000393969
,
ENSG00000196610
,
ENSG00000229493
,
ENSP00000410132
,
ENST00000411527
,
ENSP00000399594
,
ENSG00000226165
,
ENST00000430849
,
ENSP00000389067
,
ENST00000456529
,
ENSG00000232629
,
ENSG00000228254
,
ENSP00000408884
,
ENSP00000396502
,
ENSG00000230675
,
ENST00000457432
,
ENST00000432486
,
ENSP00000382569
,
ENST00000399661
,
ENST00000426733
,
ENSG00000224305
,
ENST00000438757
,
ENSG00000228813
,
ENSP00000390431
PRO
P05538
Pharos - Targets
P05538
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