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HLA class II histocompatibility antigen, DR beta 4 chain
Stable Identifier
R-HSA-2130373
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
integral component of lumenal side of endoplasmic reticulum membrane
Synonyms
HLA-DRB4, DRB4_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
MHC class II antigen presentation (Homo sapiens)
Dissociation of CANX from nonameric complex (Homo sapiens)
2xMHC II alpha beta heterodimer:alpha beta dimer:Ii trimer [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
MHC II alpha beta heterodimer [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA II beta chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DR beta 4 chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
alpha beta dimer:Ii trimer [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
MHC II alpha beta heterodimer [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA II beta chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DR beta 4 chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
2xMHC II alpha beta heterodimer:alpha beta dimer:Ii trimer:calnexin [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
MHC II alpha beta heterodimer [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA II beta chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DR beta 4 chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
alpha beta dimer:Ii trimer:calnexin [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
MHC II alpha beta heterodimer [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA II beta chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DR beta 4 chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Formation of COPII vesicle (Homo sapiens)
Nonameric complex [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
MHC II alpha beta heterodimer [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA II beta chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DR beta 4 chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Formation of MHC II alpha beta heterodimer (Homo sapiens)
HLA II beta chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DR beta 4 chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
MHC II alpha beta heterodimer [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA II beta chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DR beta 4 chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Formation of nonameric complex (Homo sapiens)
2xMHC II alpha beta heterodimer:alpha beta dimer:Ii trimer:calnexin [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
MHC II alpha beta heterodimer [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA II beta chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DR beta 4 chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
alpha beta dimer:Ii trimer:calnexin [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
MHC II alpha beta heterodimer [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA II beta chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DR beta 4 chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
MHC II alpha beta heterodimer [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA II beta chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DR beta 4 chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
alpha beta dimer:Ii trimer:calnexin [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
MHC II alpha beta heterodimer [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA II beta chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DR beta 4 chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Interaction of invariant chain trimer and MHC II alpha beta dimer (Homo sapiens)
MHC II alpha beta heterodimer [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA II beta chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DR beta 4 chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
alpha beta dimer:Ii trimer:calnexin [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
MHC II alpha beta heterodimer [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA II beta chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DR beta 4 chain [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P13762 HLA-DRB4
Gene Names
HLA-DRB4
Chain
signal peptide:1-29, chain:30-266
Reference Genes
BioGPS Gene:3126 HLA-DRB4
CTD Gene:3126 HLA-DRB4
dbSNP Gene:3126 HLA-DRB4
ENSEMBL:ENSG00000227357 HLA-DRB4
HGNC:4952 HLA-DRB4
KEGG Gene (Homo sapiens):HLA-DRB4 HLA-DRB4
KEGG Gene (Homo sapiens):hsa:3126 HLA-DRB4
Monarch:3126 HLA-DRB4
NCBI Gene:3126 HLA-DRB4
Reference Transcript
RefSeq:NM_021983.4 HLA-DRB4
RefSeq:XM_017030290.1 HLA-DRB4
Other Identifiers
0000870484
11755998_x_at
17037192
209728_3p_at
209728_at
2950023
2950025
2950057
2950060
3126
32035_at
4048248
4048272
4048275
41723_s_at
A_24_P370472
AAA35995
AAA36296
AAA59830
AAH05312
AAL48256
AAM00252
AAM00253
AAO43051
AAQ96922
AB107960
ABC66198
ACX50637
AF361548
AF361549
AH011268
AH012539
AK292151
AY394720
BAC75547
BAF84840
BC005312
BX120007
BX571807
BX927235
CAA70497
CAM25971
CAM26205
CAQ07647
CAQ07773
CR788250
DQ284431
ENSG00000227357
ENSP00000410857
ENST00000411565
EntrezGene:3126
g13529055_3p_s_at
g13529055_3p_x_at
GO:0000139
GO:0002376
GO:0002504
GO:0005764
GO:0005765
GO:0005768
GO:0005783
GO:0005789
GO:0005794
GO:0005886
GO:0006955
GO:0010008
GO:0012507
GO:0016020
GO:0016021
GO:0019882
GO:0019886
GO:0030658
GO:0030666
GO:0030669
GO:0031295
GO:0031902
GO:0032588
GO:0042613
GO:0050852
GO:0060333
GO:0071556
GQ891550
HGNC:4952
HLA-DRB4
HLA-DRB4-201
Hs.279930.1.S1_3p_x_at
ILMN_1752592
ILMN_2159694
ILMN_3228688
IPR000353
IPR003006
IPR003597
IPR007110
IPR011162
IPR013783
IPR014745
M15178
M16942
M20555
NM_021983
NP_068818
PF00969
PF07654
SM00407
SM00921
TC6_mann_hap4000159.hg
TC6_mann_hap4000161.hg
TC6_mcf_hap5000169.hg
TC6_ssto_hap7000163.hg
UPI00000725D8
Y09313
Participant Of
hasMember
HLA II beta chain [integral component of lumenal side of endoplasmic reticulum membrane]
Other forms of this molecule
HLA class II histocompatibility antigen, DR beta 4 chain [ER to Golgi transport vesicle membrane]
HLA class II histocompatibility antigen, DR beta 4 chain [Golgi membrane]
HLA class II histocompatibility antigen, DR beta 4 chain [trans-Golgi network membrane]
HLA class II histocompatibility antigen, DR beta 4 chain [transport vesicle membrane]
HLA class II histocompatibility antigen, DR beta 4 chain [clathrin-coated endocytic vesicle membrane]
HLA class II histocompatibility antigen, DR beta 4 chain [endocytic vesicle membrane]
HLA class II histocompatibility antigen, DR beta 4 chain [lysosomal membrane]
HLA class II histocompatibility antigen, DR beta 4 chain [plasma membrane]
Cross References
RefSeq
NP_068818.4
,
XP_016885779.1
GeneCards
P13762
PRO
P13762
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