Reactome | HLA class II histocompatibility antigen, DM alpha chain precursor [lysosomal membrane]

HLA class II histocompatibility antigen, DM alpha chain precursor [lysosomal membrane]

Stable Identifier

R-HSA-2130359

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

lysosomal membrane

Synonyms

2DMA_HUMAN, HLA-DMA

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P28067 HLA-DMA

Gene Names

HLA-DMA, DMA, RING6

Chain

signal peptide:1-26, chain:27-261

Reference Genes

BioGPS Gene:3108 HLA-DMA

COSMIC (genes):HLA-DMA HLA-DMA

CTD Gene:3108 HLA-DMA

dbSNP Gene:3108 HLA-DMA

ENSEMBL:ENSG00000204257 HLA-DMA

HGNC:4934 HLA-DMA

KEGG:hsa:3108 HLA-DMA

Monarch:3108 HLA-DMA

NCBI Gene:3108 HLA-DMA

OMIM:142855 HLA-DMA

UCSC:P28067 HLA-DMA

Reference Transcript

RefSeq:NM_006120.3 HLA-DMA

Other Identifiers

11716554_a_at

11745989_a_at

17018011

17037303

17042519

217478_PM_s_at

217478_s_at

2950278

2950279

2950280

2950281

2950282

2950283

2950284

2950285

2950286

2950287

2950288

2950291

2950292

2950293

2950294

2950295

2950296

3108

37344_at

8125537

8178884

8180086

A_23_P42306

A_24_P50245

GE59882

GE88155

GO:0002250

GO:0002376

GO:0002503

GO:0002504

GO:0005515

GO:0005764

GO:0005765

GO:0005768

GO:0005773

GO:0006955

GO:0009986

GO:0010008

GO:0016020

GO:0019882

GO:0019886

GO:0023026

GO:0031410

GO:0031902

GO:0042605

GO:0042613

GO:0043226

GO:0043231

GO:0050778

GO:0050870

GO:0065003

HMNXSV003012753

Hs.77522.1.S1_3p_a_at

ILMN_1695311

PH_hs_0023937

TC06004128.hg

TC6_apd_hap1000118.hg

TC6_cox_hap2000233.hg

TC6_dbb_hap3000210.hg

TC6_mann_hap4000210.hg

TC6_mcf_hap5000231.hg

TC6_qbl_hap6000237.hg

TC6_ssto_hap7000220.hg

X62744_at

Participates

as a component of

HLA-DM [lysosomal membrane] (Homo sapiens)

Inferred To

hla-dpa1 [lysosomal membrane] (Danio rerio)

HLA class II histocompatibility antigen, DM alpha chain precursor [lysosomal membrane] (Sus scrofa)

RT1-DMa [lysosomal membrane] (Rattus norvegicus)

mhc2-dma [lysosomal membrane] (Xenopus tropicalis)

si:busm1-194e12.8 [lysosomal membrane] (Danio rerio)

H2-DMa [lysosomal membrane] (Mus musculus)

Homologues of HLA class II histocompatibility antigen, DM alpha chain precursor [lysosomal membrane] (Danio rerio)

mhc2daa [lysosomal membrane] (Danio rerio)

DLA-DMA [lysosomal membrane] (Canis familiaris)

HLA-DMA [lysosomal membrane] (Bos taurus)

mhc2d8.45b1 [lysosomal membrane] (Danio rerio)

mhc2dgb [lysosomal membrane] (Danio rerio)

Cross References

RefSeq

NP_006111.2

ENSEMBL

ENSP00000404018, ENSP00000392842, ENST00000383230, ENSP00000372717, ENSP00000395349, ENST00000441375, ENST00000453490, ENSG00000243215, ENSG00000204257, ENSG00000242361, ENSG00000243189, ENSG00000242685, ENSP00000407198, ENST00000374843, ENST00000434337, ENSP00000363976, ENSP00000410591, ENST00000452615, ENST00000450601, ENSG00000243719, ENSG00000239463

OpenTargets

ENSG00000204257

GeneCards

HLA-DMA

HPA

ENSG00000204257-HLA-DMA

PRO

P28067

Pharos - Targets

P28067

GlyGen

P28067

PDB

4FQX, 4GBX, 2BC4, 1HDM

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P02686 MBP	1	MBP [cytosol] (R-HSA-9614770)	0.462	6