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Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
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Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
Data Model
Computational inferred events
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HLA class II histocompatibility antigen, DRB1-1 beta chain [trans-Golgi network membrane]
Stable Identifier
R-HSA-2130338
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
trans-Golgi network membrane
Synonyms
HLA-DRB1, 2B11_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
MHC class II antigen presentation (Homo sapiens)
Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex (Homo sapiens)
AP-1 Clathrin coated nonameric complex [trans-Golgi network membrane] (Homo sapiens)
Nonameric complex [trans-Golgi network membrane] (Homo sapiens)
MHC II alpha/beta dimer [trans-Golgi network membrane] (Homo sapiens)
HLA II beta chain [trans-Golgi network membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DRB1-1 beta chain [trans-Golgi network membrane] (Homo sapiens)
AP-1 Complex:Arf1-GTP:Clathrin Triskelion:Nonameric complex [trans-Golgi network membrane] (Homo sapiens)
Nonameric complex [trans-Golgi network membrane] (Homo sapiens)
MHC II alpha/beta dimer [trans-Golgi network membrane] (Homo sapiens)
HLA II beta chain [trans-Golgi network membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DRB1-1 beta chain [trans-Golgi network membrane] (Homo sapiens)
TGN-lysosomal vesicle coat assembly (Homo sapiens)
AP-1 Complex:Arf1-GTP:Clathrin Triskelion:Nonameric complex [trans-Golgi network membrane] (Homo sapiens)
Nonameric complex [trans-Golgi network membrane] (Homo sapiens)
MHC II alpha/beta dimer [trans-Golgi network membrane] (Homo sapiens)
HLA II beta chain [trans-Golgi network membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DRB1-1 beta chain [trans-Golgi network membrane] (Homo sapiens)
Nonameric complex [trans-Golgi network membrane] (Homo sapiens)
MHC II alpha/beta dimer [trans-Golgi network membrane] (Homo sapiens)
HLA II beta chain [trans-Golgi network membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DRB1-1 beta chain [trans-Golgi network membrane] (Homo sapiens)
TGN-lysosome vesicle uncoating and release of nonameric complex to lysosome (Homo sapiens)
TGN-lysosome vesicle with nonameric complex [trans-Golgi network membrane] (Homo sapiens)
Nonameric complex [trans-Golgi network membrane] (Homo sapiens)
MHC II alpha/beta dimer [trans-Golgi network membrane] (Homo sapiens)
HLA II beta chain [trans-Golgi network membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DRB1-1 beta chain [trans-Golgi network membrane] (Homo sapiens)
Translocation of TGN-lysosome vesicle to lysosome (Homo sapiens)
AP-1 Clathrin coated nonameric complex [trans-Golgi network membrane] (Homo sapiens)
Nonameric complex [trans-Golgi network membrane] (Homo sapiens)
MHC II alpha/beta dimer [trans-Golgi network membrane] (Homo sapiens)
HLA II beta chain [trans-Golgi network membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DRB1-1 beta chain [trans-Golgi network membrane] (Homo sapiens)
TGN-lysosome vesicle with nonameric complex [trans-Golgi network membrane] (Homo sapiens)
Nonameric complex [trans-Golgi network membrane] (Homo sapiens)
MHC II alpha/beta dimer [trans-Golgi network membrane] (Homo sapiens)
HLA II beta chain [trans-Golgi network membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DRB1-1 beta chain [trans-Golgi network membrane] (Homo sapiens)
Transport of MHC II:Ii complex along Golgi to TGN (Homo sapiens)
Nonameric complex [trans-Golgi network membrane] (Homo sapiens)
MHC II alpha/beta dimer [trans-Golgi network membrane] (Homo sapiens)
HLA II beta chain [trans-Golgi network membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DRB1-1 beta chain [trans-Golgi network membrane] (Homo sapiens)
Transport of MHC II:Ii complex to plasma membrane (Homo sapiens)
Nonameric complex [trans-Golgi network membrane] (Homo sapiens)
MHC II alpha/beta dimer [trans-Golgi network membrane] (Homo sapiens)
HLA II beta chain [trans-Golgi network membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DRB1-1 beta chain [trans-Golgi network membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P04229 HLA-DRB1
Gene Names
HLA-DRB1
Chain
signal peptide:1-29, chain:30-266
Reference Genes
COSMIC (genes):HLA-DRB1 HLA-DRB1
ENSEMBL:ENSG00000196126 HLA-DRB1
ENSEMBL_homo_sapiens_GENE:ENSG00000196126 HLA-DRB1
HGNC:4948 HLA-DRB1
OMIM:142857 HLA-DRB1
Other Identifiers
105369230
11723194_x_at
11759642_x_at
15400
17017900
1BX2
1YMM
204670_x_at
208306_3p_x_at
208306_x_at
209312_x_at
215193_x_at
2950021
2950023
2950033
2950035
2950046
2950052
2950057
2950068
2WBJ
3123
34021
4048251
4048256
4048258
4048272
4048279
4048282
4048284
4048285
4048288
4048289
4048290
4048296
4048297
41723_s_at
43151
75284_f_at
8178811
8180003
A2BFX2
AAA36279
AAA59681
AAA59801
AAA59831
AAH33827
AAI08923
AAU87979
AAU88008
AAU88023
AAU88033
AAX63460
AAX63461
ADI59573
AEK27140
AEV76920
AHW56506
AL713966
AY663395
AY663406
AY663411
AY663414
AY961072
AY961073
BC033827
BC108922
CAB015400
CAB034021
CCDS47409
D7RIG5
D7RIH8
ENSG00000196126
ENSP00000353099
ENST00000360004
EntrezGene:105369230
EntrezGene:3123
g5478215_3p_x_at
GO:0000139
GO:0001618
GO:0002376
GO:0002381
GO:0002437
GO:0002455
GO:0002504
GO:0002506
GO:0003674
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005623
GO:0005737
GO:0005764
GO:0005765
GO:0005768
GO:0005773
GO:0005783
GO:0005789
GO:0005794
GO:0005886
GO:0006810
GO:0006950
GO:0006955
GO:0007155
GO:0007165
GO:0007267
GO:0008150
GO:0008283
GO:0009897
GO:0009986
GO:0010008
GO:0012507
GO:0016020
GO:0016021
GO:0016032
GO:0016045
GO:0019882
GO:0019886
GO:0022607
GO:0023026
GO:0030658
GO:0030666
GO:0030669
GO:0031410
GO:0031902
GO:0032395
GO:0032588
GO:0032673
GO:0032689
GO:0032991
GO:0035774
GO:0042088
GO:0042130
GO:0042592
GO:0042605
GO:0042613
GO:0043226
GO:0044403
GO:0046718
GO:0050852
GO:0051262
GO:0060333
GO:0065003
GO:0070062
GO:0071556
GO:2001179
HGNC:4948
HLA-DRB1
HLA-DRB1-201
HM067861
HQ840743
Hs.279930.1.S1_3p_x_at
ILMN_1715169
ILMN_3228688
IPR000353
IPR003006
IPR003597
IPR007110
IPR011162
IPR013783
IPR014745
IPR036179
JN157603
KJ534866
LOC105369230
M16957
M17378
M20430
M28584
M33600_f_at
MIM:126200
MIM:142857
MIM:180300
MIM:181000
NM_002124
NP_002115
P01911
P01912
P13761
PF00969
PF07654
PH_hs_0034480
Q29974
Q9GIY3
SM00407
SM00921
TC06004123.hg
TC6_dbb_hap3000180.hg
TC6_dbb_hap3000208.hg
TC6_ssto_hap7000164.hg
uc003obp.5
UPI000008A1F7
X5DNQ0
Participant Of
hasMember
HLA II beta chain [trans-Golgi network membrane]
Other forms of this molecule
HLA class II histocompatibility antigen, DRB1-1 beta chain [integral component of lumenal side of endoplasmic reticulum membrane]
HLA class II histocompatibility antigen, DRB1-1 beta chain [ER to Golgi transport vesicle membrane]
HLA class II histocompatibility antigen, DRB1-1 beta chain [Golgi membrane]
HLA class II histocompatibility antigen, DRB1-1 beta chain [transport vesicle membrane]
HLA class II histocompatibility antigen, DRB1-1 beta chain [clathrin-coated endocytic vesicle membrane]
HLA class II histocompatibility antigen, DRB1-1 beta chain [endocytic vesicle membrane]
HLA class II histocompatibility antigen, DRB1-1 beta chain [lysosomal membrane]
HLA class II histocompatibility antigen, DRB1-1 beta chain [plasma membrane]
Inferred To
HLA class II histocompatibility antigen, DR beta 5 chain [trans-Golgi network membrane] (Bos taurus)
HLA class II histocompatibility antigen, DR beta 5 chain [trans-Golgi network membrane] (Canis familiaris)
HLA class II histocompatibility antigen, DR beta 5 chain [trans-Golgi network membrane] (Danio rerio)
HLA class II histocompatibility antigen, DR beta 5 chain [trans-Golgi network membrane] (Gallus gallus)
HLA class II histocompatibility antigen, DR beta 5 chain [trans-Golgi network membrane] (Mus musculus)
HLA class II histocompatibility antigen, DR beta 5 chain [trans-Golgi network membrane] (Rattus norvegicus)
HLA class II histocompatibility antigen, DR beta 5 chain [trans-Golgi network membrane] (Sus scrofa)
HLA class II histocompatibility antigen, DR beta 5 chain [trans-Golgi network membrane] (Taeniopygia guttata)
HLA class II histocompatibility antigen, DR beta 5 chain [trans-Golgi network membrane] (Xenopus tropicalis)
Homologues of HLA class II histocompatibility antigen, DR beta 5 chain [trans-Golgi network membrane] (Bos taurus)
Homologues of HLA class II histocompatibility antigen, DR beta 5 chain [trans-Golgi network membrane] (Canis familiaris)
Homologues of HLA class II histocompatibility antigen, DR beta 5 chain [trans-Golgi network membrane] (Danio rerio)
Homologues of HLA class II histocompatibility antigen, DR beta 5 chain [trans-Golgi network membrane] (Gallus gallus)
Homologues of HLA class II histocompatibility antigen, DR beta 5 chain [trans-Golgi network membrane] (Mus musculus)
Homologues of HLA class II histocompatibility antigen, DR beta 5 chain [trans-Golgi network membrane] (Rattus norvegicus)
Homologues of HLA class II histocompatibility antigen, DR beta 5 chain [trans-Golgi network membrane] (Sus scrofa)
Homologues of HLA class II histocompatibility antigen, DR beta 5 chain [trans-Golgi network membrane] (Taeniopygia guttata)
Homologues of HLA class II histocompatibility antigen, DR beta 5 chain [trans-Golgi network membrane] (Xenopus tropicalis)
Cross References
OpenTargets
ENSG00000196126
GeneCards
P04229
ZINC - Substances
2B11_HUMAN
DOCK Blaster
3QXA
,
2FSE
,
1SJE
,
4AH2
,
3L6F
,
2G9H
,
1HXY
,
2IAM
,
2OJE
,
2XN9
,
4OV5
,
3QXD
,
1PYW
,
3PGD
,
2IAN
,
3PGC
,
4FQX
,
1SJH
,
1KLU
,
1JWM
,
2ICW
,
4I5B
,
2IPK
,
1T5W
,
4X5X
,
4E41
,
4AEN
,
1T5X
,
4C56
,
1SEB
,
1R5I
,
1DLH
,
4X5W
,
1JWS
,
3S5L
,
1LO5
,
1JWU
,
4GBX
,
3S4S
,
1KLG
,
3PDO
,
1AQD
,
1FYT
,
1KG0
ZINC target
P04229
PRO
P04229
ZINC - Predictions - Purchasable
2B11_HUMAN
Orphanet
16202
PDB
4X5X
,
2IAM
,
1HXY
,
4E41
,
4OV5
,
6CQJ
,
4I5B
,
2G9H
,
1AQD
,
1R5I
,
1LO5
,
4FQX
,
3PDO
,
1SJE
,
1FYT
,
3PGC
,
3S5L
,
4X5W
,
2IAN
,
1KLG
,
2IPK
,
1JWM
,
4GBX
,
4C56
,
4AH2
,
1SJH
,
1PYW
,
2FSE
,
4AEN
,
2ICW
,
3PGD
,
2OJE
,
3QXD
,
2XN9
,
3L6F
,
3S4S
,
6CQR
,
1JWU
,
1KLU
,
1T5X
,
3QXA
,
1DLH
,
1SEB
,
1KG0
,
1T5W
,
1JWS
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