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HLA class II histocompatibility antigen, DR-1 beta chain precursor [lysosomal membrane]
Stable Identifier
R-HSA-2130310
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
lysosomal membrane
Synonyms
HB2B_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
MHC class II antigen presentation (Homo sapiens)
Cleavage of lip22 to lip10 (Homo sapiens)
MHC II:lip10 nonamer [lysosomal membrane] (Homo sapiens)
MHC II alpha/beta dimer [lysosomal membrane] (Homo sapiens)
HLA II beta chain [lysosomal membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DR-1 beta chain precursor [lysosomal membrane] (Homo sapiens)
MHC II:lip22 nonamer [lysosomal membrane] (Homo sapiens)
MHC II alpha/beta dimer [lysosomal membrane] (Homo sapiens)
HLA II beta chain [lysosomal membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DR-1 beta chain precursor [lysosomal membrane] (Homo sapiens)
Disassociation of CLIP from MHC II (Homo sapiens)
MHC II:CLIP [lysosomal membrane] (Homo sapiens)
MHC II alpha/beta dimer [lysosomal membrane] (Homo sapiens)
HLA II beta chain [lysosomal membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DR-1 beta chain precursor [lysosomal membrane] (Homo sapiens)
peptide free MHC II:HLA-DM [lysosomal membrane] (Homo sapiens)
MHC II alpha/beta dimer [lysosomal membrane] (Homo sapiens)
HLA II beta chain [lysosomal membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DR-1 beta chain precursor [lysosomal membrane] (Homo sapiens)
Generation of CLIP from lip10 (Homo sapiens)
MHC II:CLIP [lysosomal membrane] (Homo sapiens)
MHC II alpha/beta dimer [lysosomal membrane] (Homo sapiens)
HLA II beta chain [lysosomal membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DR-1 beta chain precursor [lysosomal membrane] (Homo sapiens)
MHC II:lip10 nonamer [lysosomal membrane] (Homo sapiens)
MHC II alpha/beta dimer [lysosomal membrane] (Homo sapiens)
HLA II beta chain [lysosomal membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DR-1 beta chain precursor [lysosomal membrane] (Homo sapiens)
Initial proteolyis of Ii by aspartic proteases to lip22 (Homo sapiens)
MHC II:lip22 nonamer [lysosomal membrane] (Homo sapiens)
MHC II alpha/beta dimer [lysosomal membrane] (Homo sapiens)
HLA II beta chain [lysosomal membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DR-1 beta chain precursor [lysosomal membrane] (Homo sapiens)
Nonameric complex [lysosomal membrane] (Homo sapiens)
MHC II alpha/beta dimer [lysosomal membrane] (Homo sapiens)
HLA II beta chain [lysosomal membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DR-1 beta chain precursor [lysosomal membrane] (Homo sapiens)
Loading of antigenic peptides (Homo sapiens)
peptide free MHC II:HLA-DM [lysosomal membrane] (Homo sapiens)
MHC II alpha/beta dimer [lysosomal membrane] (Homo sapiens)
HLA II beta chain [lysosomal membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DR-1 beta chain precursor [lysosomal membrane] (Homo sapiens)
peptide loaded MHC class II [lysosomal membrane] (Homo sapiens)
MHC II alpha/beta dimer [lysosomal membrane] (Homo sapiens)
HLA II beta chain [lysosomal membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DR-1 beta chain precursor [lysosomal membrane] (Homo sapiens)
TGN-lysosome vesicle uncoating and release of nonameric complex to lysosome (Homo sapiens)
Nonameric complex [lysosomal membrane] (Homo sapiens)
MHC II alpha/beta dimer [lysosomal membrane] (Homo sapiens)
HLA II beta chain [lysosomal membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DR-1 beta chain precursor [lysosomal membrane] (Homo sapiens)
Trafficking of nonameric complex in the endocytic pathway (Homo sapiens)
Nonameric complex [lysosomal membrane] (Homo sapiens)
MHC II alpha/beta dimer [lysosomal membrane] (Homo sapiens)
HLA II beta chain [lysosomal membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DR-1 beta chain precursor [lysosomal membrane] (Homo sapiens)
Transport of antigen loaded MHC II molecules to surface (Homo sapiens)
peptide loaded MHC class II [lysosomal membrane] (Homo sapiens)
MHC II alpha/beta dimer [lysosomal membrane] (Homo sapiens)
HLA II beta chain [lysosomal membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DR-1 beta chain precursor [lysosomal membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P01912 HLA-DRB1
Gene Names
HLA-DRB1
Chain
signal peptide:1-29, chain:30-266
Reference Genes
BioGPS Gene:3123 HLA-DRB1
COSMIC (genes):HLA-DRB1 HLA-DRB1
CTD Gene:3123 HLA-DRB1
dbSNP Gene:3123 HLA-DRB1
ENSEMBL:ENSG00000196126 HLA-DRB1
KEGG Gene (Homo sapiens):3123 HLA-DRB1
Monarch:3123 HLA-DRB1
NCBI Gene:3123 HLA-DRB1
UCSC:P01912 HLA-DRB1
Reference Transcript
RefSeq:NM_002124.3 HLA-DRB1
RefSeq:NM_001243965.1 HLA-DRB1
Participant Of
hasMember
HLA II beta chain [lysosomal membrane]
Other forms of this molecule
HLA class II histocompatibility antigen, DR-1 beta chain precursor [transport vesicle membrane]
HLA class II histocompatibility antigen, DR-1 beta chain precursor [clathrin-coated endocytic vesicle membrane]
HLA class II histocompatibility antigen, DR-1 beta chain precursor [endocytic vesicle membrane]
HLA class II histocompatibility antigen, DR-1 beta chain precursor [ER to Golgi transport vesicle membrane]
HLA class II histocompatibility antigen, DR-1 beta chain precursor [integral component of lumenal side of endoplasmic reticulum membrane]
HLA class II histocompatibility antigen, DR-1 beta chain precursor [Golgi membrane]
HLA class II histocompatibility antigen, DR-1 beta chain precursor [trans-Golgi network membrane]
HLA class II histocompatibility antigen, DR-1 beta chain precursor [plasma membrane]
Cross References
RefSeq
NP_001230894.1
,
NP_002115.2
OpenTargets
ENSG00000196126
GeneCards
P01912
PRO
P01912
PDB
2SEB
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