Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1)

Stable Identifier
R-HSA-2130286
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1)
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Beta-catenin is ubiquitinated by the SCF-B-TrCP1 complex.

Literature References
PubMed ID Title Journal Year
12820959 Structure of a beta-TrCP1-Skp1-beta-catenin complex: destruction motif binding and lysine specificity of the SCF(beta-TrCP1) ubiquitin ligase

Pavletich, NP, Wu, G, Schulman, BA, Harper, JW, Jeffrey, PD, Xu, G

Mol Cell 2003
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Orthologous Events
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Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1) (Drosophila melanogaster)
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Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1) (Rattus norvegicus)
Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1) (Sus scrofa)
Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1) (Xenopus tropicalis)
Authored
Kimelman, D  (2007-04-03)
Reviewed
Pagano, M  (2007-04-27)
Created
Rothfels, K  (2012-02-21)
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