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3x4Hyp-3Hyp-GalHyl-COL6A1 [extracellular region]
Stable Identifier
R-HSA-2127538
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
3,4-Hyp 5-Gal-Hyl collagen alpha-1(VI) chain
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Nervous system development (Homo sapiens)
Axon guidance (Homo sapiens)
NCAM signaling for neurite out-growth (Homo sapiens)
NCAM1 interactions (Homo sapiens)
Interaction of NCAM1 with collagens (Homo sapiens)
Collagens [extracellular region] (Homo sapiens)
Tropocollagen type VI [extracellular region] (Homo sapiens)
Collagen alpha-1(VI) chains [extracellular region] (Homo sapiens)
3x4Hyp-3Hyp-GalHyl-COL6A1 [extracellular region] (Homo sapiens)
NCAM-1:Collagen complex [plasma membrane] (Homo sapiens)
Collagens [extracellular region] (Homo sapiens)
Tropocollagen type VI [extracellular region] (Homo sapiens)
Collagen alpha-1(VI) chains [extracellular region] (Homo sapiens)
3x4Hyp-3Hyp-GalHyl-COL6A1 [extracellular region] (Homo sapiens)
Extracellular matrix organization (Homo sapiens)
Collagen formation (Homo sapiens)
Assembly of collagen fibrils and other multimeric structures (Homo sapiens)
Formation of collagen networks (Homo sapiens)
Collagen networks [extracellular region] (Homo sapiens)
Collagen type VI network [extracellular region] (Homo sapiens)
Collagen type VI tetramer [extracellular region] (Homo sapiens)
Tropocollagen type VI dimer [extracellular region] (Homo sapiens)
Tropocollagen type VI [extracellular region] (Homo sapiens)
Collagen alpha-1(VI) chains [extracellular region] (Homo sapiens)
3x4Hyp-3Hyp-GalHyl-COL6A1 [extracellular region] (Homo sapiens)
Network forming tropocollagens [extracellular region] (Homo sapiens)
Collagen type VI tetramer [extracellular region] (Homo sapiens)
Tropocollagen type VI dimer [extracellular region] (Homo sapiens)
Tropocollagen type VI [extracellular region] (Homo sapiens)
Collagen alpha-1(VI) chains [extracellular region] (Homo sapiens)
3x4Hyp-3Hyp-GalHyl-COL6A1 [extracellular region] (Homo sapiens)
Collagen biosynthesis and modifying enzymes (Homo sapiens)
Secretion of collagens (Homo sapiens)
Collagens and tropocollagens [extracellular region] (Homo sapiens)
Collagen type VI tetramer [extracellular region] (Homo sapiens)
Tropocollagen type VI dimer [extracellular region] (Homo sapiens)
Tropocollagen type VI [extracellular region] (Homo sapiens)
Collagen alpha-1(VI) chains [extracellular region] (Homo sapiens)
3x4Hyp-3Hyp-GalHyl-COL6A1 [extracellular region] (Homo sapiens)
Degradation of the extracellular matrix (Homo sapiens)
Collagen degradation (Homo sapiens)
Collagen type VI degradation by MMP2,9,11 (Homo sapiens)
Collagen type VI fibril [extracellular region] (Homo sapiens)
Collagen type VI tetramer [extracellular region] (Homo sapiens)
Tropocollagen type VI dimer [extracellular region] (Homo sapiens)
Tropocollagen type VI [extracellular region] (Homo sapiens)
Collagen alpha-1(VI) chains [extracellular region] (Homo sapiens)
3x4Hyp-3Hyp-GalHyl-COL6A1 [extracellular region] (Homo sapiens)
ECM proteoglycans (Homo sapiens)
BGN binds Collagen types I, VI, (IX) (Homo sapiens)
BGN:Collagen types I, VI, (IX) [extracellular region] (Homo sapiens)
Collagen types I, VI, (IX) [extracellular region] (Homo sapiens)
Collagen type VI network [extracellular region] (Homo sapiens)
Collagen type VI tetramer [extracellular region] (Homo sapiens)
Tropocollagen type VI dimer [extracellular region] (Homo sapiens)
Tropocollagen type VI [extracellular region] (Homo sapiens)
Collagen alpha-1(VI) chains [extracellular region] (Homo sapiens)
3x4Hyp-3Hyp-GalHyl-COL6A1 [extracellular region] (Homo sapiens)
Collagen types I, VI, (IX) [extracellular region] (Homo sapiens)
Collagen type VI network [extracellular region] (Homo sapiens)
Collagen type VI tetramer [extracellular region] (Homo sapiens)
Tropocollagen type VI dimer [extracellular region] (Homo sapiens)
Tropocollagen type VI [extracellular region] (Homo sapiens)
Collagen alpha-1(VI) chains [extracellular region] (Homo sapiens)
3x4Hyp-3Hyp-GalHyl-COL6A1 [extracellular region] (Homo sapiens)
DCN binds collagen I, II, III, VI fibrils (Homo sapiens)
Collagen type I, II, III, VI fibrils [extracellular region] (Homo sapiens)
Collagen type VI fibril [extracellular region] (Homo sapiens)
Collagen type VI tetramer [extracellular region] (Homo sapiens)
Tropocollagen type VI dimer [extracellular region] (Homo sapiens)
Tropocollagen type VI [extracellular region] (Homo sapiens)
Collagen alpha-1(VI) chains [extracellular region] (Homo sapiens)
3x4Hyp-3Hyp-GalHyl-COL6A1 [extracellular region] (Homo sapiens)
DCN:Collagen type I, II, III, VI fibrils [extracellular region] (Homo sapiens)
Collagen type I, II, III, VI fibrils [extracellular region] (Homo sapiens)
Collagen type VI fibril [extracellular region] (Homo sapiens)
Collagen type VI tetramer [extracellular region] (Homo sapiens)
Tropocollagen type VI dimer [extracellular region] (Homo sapiens)
Tropocollagen type VI [extracellular region] (Homo sapiens)
Collagen alpha-1(VI) chains [extracellular region] (Homo sapiens)
3x4Hyp-3Hyp-GalHyl-COL6A1 [extracellular region] (Homo sapiens)
VTN binds collagens I, IV and VI (Homo sapiens)
Collagen type I,IV,VI [extracellular region] (Homo sapiens)
Collagen type VI fibril [extracellular region] (Homo sapiens)
Collagen type VI tetramer [extracellular region] (Homo sapiens)
Tropocollagen type VI dimer [extracellular region] (Homo sapiens)
Tropocollagen type VI [extracellular region] (Homo sapiens)
Collagen alpha-1(VI) chains [extracellular region] (Homo sapiens)
3x4Hyp-3Hyp-GalHyl-COL6A1 [extracellular region] (Homo sapiens)
VTN:Collagen type I,IV,VI [extracellular region] (Homo sapiens)
Collagen type I,IV,VI [extracellular region] (Homo sapiens)
Collagen type VI fibril [extracellular region] (Homo sapiens)
Collagen type VI tetramer [extracellular region] (Homo sapiens)
Tropocollagen type VI dimer [extracellular region] (Homo sapiens)
Tropocollagen type VI [extracellular region] (Homo sapiens)
Collagen alpha-1(VI) chains [extracellular region] (Homo sapiens)
3x4Hyp-3Hyp-GalHyl-COL6A1 [extracellular region] (Homo sapiens)
Integrin cell surface interactions (Homo sapiens)
Collagen types III, IV, V, VI, VIII, IX, XVI bind integrins alpha1beta1 and alpha2beta1 (Homo sapiens)
Collagen types III, IV, V, VI, VIII, IX, XVI [extracellular region] (Homo sapiens)
Collagen type VI network [extracellular region] (Homo sapiens)
Collagen type VI tetramer [extracellular region] (Homo sapiens)
Tropocollagen type VI dimer [extracellular region] (Homo sapiens)
Tropocollagen type VI [extracellular region] (Homo sapiens)
Collagen alpha-1(VI) chains [extracellular region] (Homo sapiens)
3x4Hyp-3Hyp-GalHyl-COL6A1 [extracellular region] (Homo sapiens)
Collagen types III, IV, V, VI, VIII, IX, XVI:Integrins alpha1beta 1, alpha2beta1 [plasma membrane] (Homo sapiens)
Collagen types III, IV, V, VI, VIII, IX, XVI [extracellular region] (Homo sapiens)
Collagen type VI network [extracellular region] (Homo sapiens)
Collagen type VI tetramer [extracellular region] (Homo sapiens)
Tropocollagen type VI dimer [extracellular region] (Homo sapiens)
Tropocollagen type VI [extracellular region] (Homo sapiens)
Collagen alpha-1(VI) chains [extracellular region] (Homo sapiens)
3x4Hyp-3Hyp-GalHyl-COL6A1 [extracellular region] (Homo sapiens)
Collagen types VI, IX bind integrin alpha10beta1 (Homo sapiens)
Collagen tupe VI network, Collagen type IX:Integrin alpha10beta1 [plasma membrane] (Homo sapiens)
Collagen type VI network, Collagen type IX [extracellular region] (Homo sapiens)
Collagen type VI network [extracellular region] (Homo sapiens)
Collagen type VI tetramer [extracellular region] (Homo sapiens)
Tropocollagen type VI dimer [extracellular region] (Homo sapiens)
Tropocollagen type VI [extracellular region] (Homo sapiens)
Collagen alpha-1(VI) chains [extracellular region] (Homo sapiens)
3x4Hyp-3Hyp-GalHyl-COL6A1 [extracellular region] (Homo sapiens)
Collagen type VI network, Collagen type IX [extracellular region] (Homo sapiens)
Collagen type VI network [extracellular region] (Homo sapiens)
Collagen type VI tetramer [extracellular region] (Homo sapiens)
Tropocollagen type VI dimer [extracellular region] (Homo sapiens)
Tropocollagen type VI [extracellular region] (Homo sapiens)
Collagen alpha-1(VI) chains [extracellular region] (Homo sapiens)
3x4Hyp-3Hyp-GalHyl-COL6A1 [extracellular region] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by PDGF (Homo sapiens)
PDGF binds to extracellular matrix proteins (Homo sapiens)
Extracellular matrix ligands [extracellular region] (Homo sapiens)
Collagens [extracellular region] (Homo sapiens)
Tropocollagen type VI [extracellular region] (Homo sapiens)
Collagen alpha-1(VI) chains [extracellular region] (Homo sapiens)
3x4Hyp-3Hyp-GalHyl-COL6A1 [extracellular region] (Homo sapiens)
PDGF A and B chains:ECM complex [extracellular region] (Homo sapiens)
Extracellular matrix ligands [extracellular region] (Homo sapiens)
Collagens [extracellular region] (Homo sapiens)
Tropocollagen type VI [extracellular region] (Homo sapiens)
Collagen alpha-1(VI) chains [extracellular region] (Homo sapiens)
3x4Hyp-3Hyp-GalHyl-COL6A1 [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:P12109 COL6A1
Gene Names
COL6A1
Chain
signal peptide:1-19, chain:20-1028
Reference Genes
BioGPS Gene:1291 COL6A1
COSMIC (genes):COL6A1 COL6A1
CTD Gene:1291 COL6A1
dbSNP Gene:1291 COL6A1
ENSEMBL:ENSG00000142156 COL6A1
HGNC:2211 COL6A1
KEGG:hsa:1291 COL6A1
Monarch:1291 COL6A1
NCBI Gene:1291 COL6A1
OMIM:120220 COL6A1
UCSC:P12109 COL6A1
Reference Transcript
RefSeq:NM_001848.2 COL6A1
Other Identifiers
11715403_a_at
11715404_a_at
11715405_x_at
11715406_a_at
11752383_a_at
11752384_s_at
1291
16923842
212091_PM_s_at
212091_s_at
212937_3p_s_at
212937_PM_s_at
212937_s_at
212938_PM_at
212938_at
212940_PM_at
212940_at
213428_PM_s_at
213428_s_at
38722_at
3924373
3924374
3924375
3924376
3924377
3924379
3924380
3924381
3924382
3924383
3924384
3924385
3924386
3924387
3924388
3924389
3924391
3924392
3924393
3924395
3924396
3924397
3924398
3924399
3924400
3924401
3924402
3924403
3924404
3924405
3924406
3924407
3924408
3924409
3924410
3924411
3924413
3924414
3924415
3924416
41350_at
57615_at
80349_s_at
8069269
A_14_P101156
A_14_P136963
A_24_P331918
A_32_P32254
GE61971
GO:0000302
GO:0000902
GO:0001503
GO:0001649
GO:0001942
GO:0002023
GO:0003012
GO:0003016
GO:0005198
GO:0005515
GO:0005518
GO:0005576
GO:0005581
GO:0005589
GO:0005604
GO:0005739
GO:0005764
GO:0005765
GO:0005773
GO:0005783
GO:0005788
GO:0005886
GO:0005975
GO:0006091
GO:0006096
GO:0006099
GO:0006103
GO:0006112
GO:0006914
GO:0006915
GO:0006954
GO:0007005
GO:0007155
GO:0007338
GO:0007422
GO:0007507
GO:0007517
GO:0007519
GO:0007623
GO:0008286
GO:0008361
GO:0009410
GO:0009411
GO:0009611
GO:0009612
GO:0009636
GO:0010467
GO:0010657
GO:0012501
GO:0014823
GO:0014850
GO:0016020
GO:0016529
GO:0019226
GO:0022011
GO:0022414
GO:0030016
GO:0030020
GO:0030154
GO:0030198
GO:0030199
GO:0030262
GO:0030282
GO:0030312
GO:0030324
GO:0031012
GO:0032496
GO:0032963
GO:0032991
GO:0033993
GO:0035987
GO:0036022
GO:0036293
GO:0042383
GO:0043226
GO:0043403
GO:0043491
GO:0043588
GO:0048009
GO:0048265
GO:0048286
GO:0048407
GO:0048630
GO:0048741
GO:0048771
GO:0048856
GO:0048872
GO:0050877
GO:0050954
GO:0051216
GO:0051262
GO:0051402
GO:0051882
GO:0055001
GO:0055085
GO:0055086
GO:0060065
GO:0060070
GO:0060348
GO:0060425
GO:0060487
GO:0060538
GO:0060612
GO:0061024
GO:0061061
GO:0062023
GO:0065003
GO:0070062
GO:0070341
GO:0070836
GO:0071230
GO:0071711
GO:0071965
GO:0072593
GO:0085029
GO:0097009
GO:0097708
GO:0098528
GO:1901135
GO:1901652
GO:1904026
GO:1904583
GO:1904975
GO:1990542
HMNXSV003034787
Hs.108885.0.A1_3p_a_at
Hs.108885.1.S1_3p_a_at
Hs.25459.0.S1_3p_at
Hs.25459.0.S2_3p_at
Hs.25459.0.S2_3p_s_at
ILMN_1732151
PH_hs_0025035
TC21000249.hg
X15880_at
Participates
as a member of
Collagen alpha-1(VI) chains [extracellular region] (Homo sapiens)
Other forms of this molecule
GalHyl-COL6A1 [endoplasmic reticulum lumen]
3x4Hyp-GlcGalHyl-COL6A1 [endoplasmic reticulum lumen]
GlcGalHyl-COL6A1 [endoplasmic reticulum lumen]
3x4Hyp-GalHyl-COL6A1 [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-GalHyl-COL6A1 [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-GlcGalHyl-COL6A1 [endoplasmic reticulum lumen]
COL6A1 [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-GlcGalHyl-COL6A1 [extracellular region]
3x4Hyp-5Hyl-COL6A1 [extracellular region]
GalHyl-COL6A1 [extracellular region]
3x4Hyp-GlcGalHyl-COL6A1 [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL6A1 [extracellular region]
3x4Hyp-COL6A1 [extracellular region]
COL6A1 [extracellular region]
3x4Hyp-3Hyp-COL6A1 [extracellular region]
3x4Hyp-GalHyl-COL6A1 [extracellular region]
GlcGalHyl-COL6A1 [extracellular region]
5Hyl-COL6A1 [extracellular region]
3x4Hyp-GlcGalHyl-COL6A1(?-1028) [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL6A1(?-1028) [extracellular region]
3x4Hyp-3Hyp-COL6A1(?-1028) [extracellular region]
3x4Hyp-5Hyl-COL6A1(20-?) [extracellular region]
5Hyl-COL6A1(20-?) [extracellular region]
3x4Hyp-3Hyp-COL6A1(20-?) [extracellular region]
3x4Hyp-GalHyl-COL6A1(?-1028) [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL6A1(20-?) [extracellular region]
3x4Hyp-GalHyl-COL6A1(20-?) [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL6A1(?-1028) [extracellular region]
GalHyl-COL6A1(?-1028) [extracellular region]
5Hyl-COL6A1(?-1028) [extracellular region]
3x4Hyp-GlcGalHyl-COL6A1(20-?) [extracellular region]
GlcGalHyl-COL6A1(?-1028) [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL6A1(20-?) [extracellular region]
COL6A1(20-?) [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL6A1(?-1028) [extracellular region]
GlcGalHyl-COL6A1(20-?) [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL6A1(20-?) [extracellular region]
3x4Hyp-5Hyl-COL6A1(?-1028) [extracellular region]
GalHyl-COL6A1(20-?) [extracellular region]
3x4Hyp-COL6A1(20-?) [extracellular region]
COL6A1(?-1028) [extracellular region]
3x4Hyp-COL6A1(?-1028) [extracellular region]
5Hyl-COL6A1 [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-5Hyl-COL6A1 [endoplasmic reticulum lumen]
3x4Hyp-5Hyl-COL6A1 [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-COL6A1 [endoplasmic reticulum lumen]
3x4Hyp-COL6A1 [endoplasmic reticulum lumen]
Inferred To
Col6a1 [extracellular region]
(Mus musculus)
3x4Hyp-3Hyp-GalHyl-COL6A1 [extracellular region]
(Caenorhabditis elegans)
3x4Hyp-3Hyp-GalHyl-COL6A1 [extracellular region]
(Dictyostelium discoideum)
COL6A1 [extracellular region]
(Bos taurus)
COL6A1 [extracellular region]
(Sus scrofa)
Modified Residues
Name
(2S,4R)-4-hydroxyproline at unknown position
PsiMod Name
(2S,4R)-4-hydroxyproline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline
Name
(2S,4R)-4-hydroxyproline at unknown position
PsiMod Name
(2S,4R)-4-hydroxyproline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline
Name
(2S,4R)-4-hydroxyproline at unknown position
PsiMod Name
(2S,4R)-4-hydroxyproline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline
Name
(2S,3S)-3-hydroxyproline at unknown position
PsiMod Name
(2S,3S)-3-hydroxyproline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to 3-hydroxy-L-proline.
Name
O5-galactosyl-L-hydroxylysine at unknown position
PsiMod Name
O5-galactosyl-L-hydroxylysine
PsiMod Definition
A protein modification that effectively converts an L-lysine residue to O5-galactosyl-L-hydroxylysine.
Cross References
RefSeq
NP_001839.2
OpenTargets
ENSG00000142156
ENSEMBL
ENSP00000355180
,
ENST00000361866
HPA
ENSG00000142156-COL6A1
PRO
P12109
Pharos - Targets
P12109
GlyGen
P12109
Orphanet
COL6A1
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P08253 MMP2
5
MMP2(110-660) [extracellular region]
(R-HSA-381456)
MMP2(30-660) [extracellular region]
(R-HSA-1604364)
MMP2(67-660) [extracellular region]
(R-HSA-1604345)
MMP2(30-66) [extracellular region]
(R-HSA-1604347)
MMP2(67-109) [extracellular region]
(R-HSA-1604371)
0.527
2
UniProt:P59665 DEFA1
9
DEFA1(20-94) [Golgi lumen]
(R-HSA-1467282)
DEFA1(66-94) [Golgi lumen]
(R-HSA-975663)
DEFA1(20-65) [Golgi lumen]
(R-HSA-8864970)
DEFA1(1-94) [Golgi lumen]
(R-HSA-1467215)
DEFA1(66-94) [extracellular region]
(R-HSA-1461998)
DEFA1(66-94) [azurophil granule lumen]
(R-HSA-1470038)
DEFA1(65-94) [extracellular region]
(R-HSA-1462022)
omega-N-(ADP-ribosyl)-L-arginine-DEFA1(65-94) [extracellular region]
(R-HSA-1972397)
DEFA1(65-94) [azurophil granule lumen]
(R-HSA-1470053)
0.527
2
UniProt:P14780 MMP9
8
MMP9(107-707) [extracellular region]
(R-HSA-668812)
MMP9(20-707) [extracellular region]
(R-HSA-1604376)
MMP9(20-106) [extracellular region]
(R-HSA-1604713)
MMP9(20-59) [extracellular region]
(R-HSA-1604685)
MMP9(60-707) [extracellular region]
(R-HSA-1604726)
MMP9(60-106) [extracellular region]
(R-HSA-1604699)
MMP9 [tertiary granule lumen]
(R-HSA-6800181)
MMP9 [ficolin-1-rich granule lumen]
(R-HSA-6800973)
0.527
2
UniProt:P0DTC8 8
2
8 [extracellular region]
(R-COV-9755410)
8 [endoplasmic reticulum lumen]
(R-COV-9727283)
0.527
2
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