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GlcGalHyl-COL4A4 [extracellular region]
Stable Identifier
R-HSA-2127443
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
Glu-Gal-Hyl-collagen alpha-4(IV) chain
Locations in the PathwayBrowser
Expand all
Extracellular matrix organization (Homo sapiens)
Collagen formation (Homo sapiens)
Assembly of collagen fibrils and other multimeric structures (Homo sapiens)
Anchoring fibril formation (Homo sapiens)
Collagen type VII binds laminin-322 and collagen IV (Homo sapiens)
Anchoring fibril complex [extracellular region] (Homo sapiens)
Collagen IV [extracellular region] (Homo sapiens)
Collagen type IV alpha3.alpha4.alpha5 network [extracellular region] (Homo sapiens)
Tropocollagen alpha-3(IV).alpha-4(IV).alpha-5(IV) [extracellular region] (Homo sapiens)
Collagen alpha-4(IV) chains [extracellular region] (Homo sapiens)
GlcGalHyl-COL4A4 [extracellular region] (Homo sapiens)
Collagen IV [extracellular region] (Homo sapiens)
Collagen type IV alpha3.alpha4.alpha5 network [extracellular region] (Homo sapiens)
Tropocollagen alpha-3(IV).alpha-4(IV).alpha-5(IV) [extracellular region] (Homo sapiens)
Collagen alpha-4(IV) chains [extracellular region] (Homo sapiens)
GlcGalHyl-COL4A4 [extracellular region] (Homo sapiens)
Crosslinking of collagen fibrils (Homo sapiens)
Collagen type IV sulfilimine cross-linking by peroxidasin (Homo sapiens)
Collagen IV [extracellular region] (Homo sapiens)
Collagen type IV alpha3.alpha4.alpha5 network [extracellular region] (Homo sapiens)
Tropocollagen alpha-3(IV).alpha-4(IV).alpha-5(IV) [extracellular region] (Homo sapiens)
Collagen alpha-4(IV) chains [extracellular region] (Homo sapiens)
GlcGalHyl-COL4A4 [extracellular region] (Homo sapiens)
Collagen type IV networks with sulfilimine cross-links [extracellular region] (Homo sapiens)
Sulfilimine-containing collagen type IV alpha3.alpha4.alpha5 network [extracellular region] (Homo sapiens)
Tropocollagen alpha-3(IV).alpha-4(IV).alpha-5(IV) with or without sulfilimine cross-links [extracellular region] (Homo sapiens)
Tropocollagen alpha-3(IV).alpha-4(IV).alpha-5(IV) [extracellular region] (Homo sapiens)
Collagen alpha-4(IV) chains [extracellular region] (Homo sapiens)
GlcGalHyl-COL4A4 [extracellular region] (Homo sapiens)
Formation of collagen networks (Homo sapiens)
Collagen networks [extracellular region] (Homo sapiens)
Collagen IV [extracellular region] (Homo sapiens)
Collagen type IV alpha3.alpha4.alpha5 network [extracellular region] (Homo sapiens)
Tropocollagen alpha-3(IV).alpha-4(IV).alpha-5(IV) [extracellular region] (Homo sapiens)
Collagen alpha-4(IV) chains [extracellular region] (Homo sapiens)
GlcGalHyl-COL4A4 [extracellular region] (Homo sapiens)
Network forming tropocollagens [extracellular region] (Homo sapiens)
Tropocollagen type IV [extracellular region] (Homo sapiens)
Tropocollagen alpha-3(IV).alpha-4(IV).alpha-5(IV) [extracellular region] (Homo sapiens)
Collagen alpha-4(IV) chains [extracellular region] (Homo sapiens)
GlcGalHyl-COL4A4 [extracellular region] (Homo sapiens)
Degradation of the extracellular matrix (Homo sapiens)
Collagen degradation (Homo sapiens)
Collagen type IV degradation by MMP2,3,4,9,10,12 (Homo sapiens)
Collagen IV [extracellular region] (Homo sapiens)
Collagen type IV alpha3.alpha4.alpha5 network [extracellular region] (Homo sapiens)
Tropocollagen alpha-3(IV).alpha-4(IV).alpha-5(IV) [extracellular region] (Homo sapiens)
Collagen alpha-4(IV) chains [extracellular region] (Homo sapiens)
GlcGalHyl-COL4A4 [extracellular region] (Homo sapiens)
ECM proteoglycans (Homo sapiens)
VTN binds collagens I, IV and VI (Homo sapiens)
Collagen type I,IV,VI [extracellular region] (Homo sapiens)
Collagen IV [extracellular region] (Homo sapiens)
Collagen type IV alpha3.alpha4.alpha5 network [extracellular region] (Homo sapiens)
Tropocollagen alpha-3(IV).alpha-4(IV).alpha-5(IV) [extracellular region] (Homo sapiens)
Collagen alpha-4(IV) chains [extracellular region] (Homo sapiens)
GlcGalHyl-COL4A4 [extracellular region] (Homo sapiens)
VTN:Collagen type I,IV,VI [extracellular region] (Homo sapiens)
Collagen type I,IV,VI [extracellular region] (Homo sapiens)
Collagen IV [extracellular region] (Homo sapiens)
Collagen type IV alpha3.alpha4.alpha5 network [extracellular region] (Homo sapiens)
Tropocollagen alpha-3(IV).alpha-4(IV).alpha-5(IV) [extracellular region] (Homo sapiens)
Collagen alpha-4(IV) chains [extracellular region] (Homo sapiens)
GlcGalHyl-COL4A4 [extracellular region] (Homo sapiens)
FN1 binds Collagen types I-V, VII (Homo sapiens)
Collagen types I-V, VII [extracellular region] (Homo sapiens)
Collagen IV [extracellular region] (Homo sapiens)
Collagen type IV alpha3.alpha4.alpha5 network [extracellular region] (Homo sapiens)
Tropocollagen alpha-3(IV).alpha-4(IV).alpha-5(IV) [extracellular region] (Homo sapiens)
Collagen alpha-4(IV) chains [extracellular region] (Homo sapiens)
GlcGalHyl-COL4A4 [extracellular region] (Homo sapiens)
FN1(32-2386):Collagen types I-V, VII [extracellular region] (Homo sapiens)
Collagen types I-V, VII [extracellular region] (Homo sapiens)
Collagen IV [extracellular region] (Homo sapiens)
Collagen type IV alpha3.alpha4.alpha5 network [extracellular region] (Homo sapiens)
Tropocollagen alpha-3(IV).alpha-4(IV).alpha-5(IV) [extracellular region] (Homo sapiens)
Collagen alpha-4(IV) chains [extracellular region] (Homo sapiens)
GlcGalHyl-COL4A4 [extracellular region] (Homo sapiens)
Integrin cell surface interactions (Homo sapiens)
Collagen type IV binds integrin alpha10beta1 (Homo sapiens)
Collagen IV [extracellular region] (Homo sapiens)
Collagen type IV alpha3.alpha4.alpha5 network [extracellular region] (Homo sapiens)
Tropocollagen alpha-3(IV).alpha-4(IV).alpha-5(IV) [extracellular region] (Homo sapiens)
Collagen alpha-4(IV) chains [extracellular region] (Homo sapiens)
GlcGalHyl-COL4A4 [extracellular region] (Homo sapiens)
Collagen type IV networks:Integrin alpha10beta1 [plasma membrane] (Homo sapiens)
Collagen IV [extracellular region] (Homo sapiens)
Collagen type IV alpha3.alpha4.alpha5 network [extracellular region] (Homo sapiens)
Tropocollagen alpha-3(IV).alpha-4(IV).alpha-5(IV) [extracellular region] (Homo sapiens)
Collagen alpha-4(IV) chains [extracellular region] (Homo sapiens)
GlcGalHyl-COL4A4 [extracellular region] (Homo sapiens)
Collagen type IV networks bind integrins alpha1beta1, alpha2beta1 (Homo sapiens)
Collagen IV [extracellular region] (Homo sapiens)
Collagen type IV alpha3.alpha4.alpha5 network [extracellular region] (Homo sapiens)
Tropocollagen alpha-3(IV).alpha-4(IV).alpha-5(IV) [extracellular region] (Homo sapiens)
Collagen alpha-4(IV) chains [extracellular region] (Homo sapiens)
GlcGalHyl-COL4A4 [extracellular region] (Homo sapiens)
Integrins alpha1beta1, alpha2beta1:Collagen type IV networks:Mg2+ [plasma membrane] (Homo sapiens)
Collagen IV [extracellular region] (Homo sapiens)
Collagen type IV alpha3.alpha4.alpha5 network [extracellular region] (Homo sapiens)
Tropocollagen alpha-3(IV).alpha-4(IV).alpha-5(IV) [extracellular region] (Homo sapiens)
Collagen alpha-4(IV) chains [extracellular region] (Homo sapiens)
GlcGalHyl-COL4A4 [extracellular region] (Homo sapiens)
Collagen types III, IV, V, VI, VIII, IX, XVI bind integrins alpha1beta1 and alpha2beta1 (Homo sapiens)
Collagen types III, IV, V, VI, VIII, IX, XVI [extracellular region] (Homo sapiens)
Collagen IV [extracellular region] (Homo sapiens)
Collagen type IV alpha3.alpha4.alpha5 network [extracellular region] (Homo sapiens)
Tropocollagen alpha-3(IV).alpha-4(IV).alpha-5(IV) [extracellular region] (Homo sapiens)
Collagen alpha-4(IV) chains [extracellular region] (Homo sapiens)
GlcGalHyl-COL4A4 [extracellular region] (Homo sapiens)
Collagen types III, IV, V, VI, VIII, IX, XVI:Integrins alpha1beta 1, alpha2beta1 [plasma membrane] (Homo sapiens)
Collagen types III, IV, V, VI, VIII, IX, XVI [extracellular region] (Homo sapiens)
Collagen IV [extracellular region] (Homo sapiens)
Collagen type IV alpha3.alpha4.alpha5 network [extracellular region] (Homo sapiens)
Tropocollagen alpha-3(IV).alpha-4(IV).alpha-5(IV) [extracellular region] (Homo sapiens)
Collagen alpha-4(IV) chains [extracellular region] (Homo sapiens)
GlcGalHyl-COL4A4 [extracellular region] (Homo sapiens)
Laminin interactions (Homo sapiens)
Collagen type VII binds collagen type IV (Homo sapiens)
Collagen IV [extracellular region] (Homo sapiens)
Collagen type IV alpha3.alpha4.alpha5 network [extracellular region] (Homo sapiens)
Tropocollagen alpha-3(IV).alpha-4(IV).alpha-5(IV) [extracellular region] (Homo sapiens)
Collagen alpha-4(IV) chains [extracellular region] (Homo sapiens)
GlcGalHyl-COL4A4 [extracellular region] (Homo sapiens)
Collagen type IV networks:Collagen type VII fibril [extracellular region] (Homo sapiens)
Collagen IV [extracellular region] (Homo sapiens)
Collagen type IV alpha3.alpha4.alpha5 network [extracellular region] (Homo sapiens)
Tropocollagen alpha-3(IV).alpha-4(IV).alpha-5(IV) [extracellular region] (Homo sapiens)
Collagen alpha-4(IV) chains [extracellular region] (Homo sapiens)
GlcGalHyl-COL4A4 [extracellular region] (Homo sapiens)
Laminin-111 binds collagen type IV (Homo sapiens)
Collagen IV [extracellular region] (Homo sapiens)
Collagen type IV alpha3.alpha4.alpha5 network [extracellular region] (Homo sapiens)
Tropocollagen alpha-3(IV).alpha-4(IV).alpha-5(IV) [extracellular region] (Homo sapiens)
Collagen alpha-4(IV) chains [extracellular region] (Homo sapiens)
GlcGalHyl-COL4A4 [extracellular region] (Homo sapiens)
Collagen type IV network:Laminin-1 [extracellular region] (Homo sapiens)
Collagen IV [extracellular region] (Homo sapiens)
Collagen type IV alpha3.alpha4.alpha5 network [extracellular region] (Homo sapiens)
Tropocollagen alpha-3(IV).alpha-4(IV).alpha-5(IV) [extracellular region] (Homo sapiens)
Collagen alpha-4(IV) chains [extracellular region] (Homo sapiens)
GlcGalHyl-COL4A4 [extracellular region] (Homo sapiens)
Laminins:Nidogens binds collagen type IV networks (Homo sapiens)
Collagen IV [extracellular region] (Homo sapiens)
Collagen type IV alpha3.alpha4.alpha5 network [extracellular region] (Homo sapiens)
Tropocollagen alpha-3(IV).alpha-4(IV).alpha-5(IV) [extracellular region] (Homo sapiens)
Collagen alpha-4(IV) chains [extracellular region] (Homo sapiens)
GlcGalHyl-COL4A4 [extracellular region] (Homo sapiens)
Laminins with gamma-1, gamma-3:Nidogens:Collagen type IV network [extracellular region] (Homo sapiens)
Collagen IV [extracellular region] (Homo sapiens)
Collagen type IV alpha3.alpha4.alpha5 network [extracellular region] (Homo sapiens)
Tropocollagen alpha-3(IV).alpha-4(IV).alpha-5(IV) [extracellular region] (Homo sapiens)
Collagen alpha-4(IV) chains [extracellular region] (Homo sapiens)
GlcGalHyl-COL4A4 [extracellular region] (Homo sapiens)
Non-integrin membrane-ECM interactions (Homo sapiens)
DDR1 binds collagen type I, II, III, IV, V, XI fibrils (Homo sapiens)
Collagen type I, II, III, IV, V, XI fibrils [extracellular region] (Homo sapiens)
Collagen IV [extracellular region] (Homo sapiens)
Collagen type IV alpha3.alpha4.alpha5 network [extracellular region] (Homo sapiens)
Tropocollagen alpha-3(IV).alpha-4(IV).alpha-5(IV) [extracellular region] (Homo sapiens)
Collagen alpha-4(IV) chains [extracellular region] (Homo sapiens)
GlcGalHyl-COL4A4 [extracellular region] (Homo sapiens)
DDR1 dimer:Collagen type I, II, III, IV, V, XI fibrils [plasma membrane] (Homo sapiens)
Collagen type I, II, III, IV, V, XI fibrils [extracellular region] (Homo sapiens)
Collagen IV [extracellular region] (Homo sapiens)
Collagen type IV alpha3.alpha4.alpha5 network [extracellular region] (Homo sapiens)
Tropocollagen alpha-3(IV).alpha-4(IV).alpha-5(IV) [extracellular region] (Homo sapiens)
Collagen alpha-4(IV) chains [extracellular region] (Homo sapiens)
GlcGalHyl-COL4A4 [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:P53420 COL4A4
Gene Names
COL4A4
Chain
signal peptide:1-38, chain:39-1690
Reference Genes
BioGPS Gene:1286 COL4A4
COSMIC (genes):COL4A4 COL4A4
CTD Gene:1286 COL4A4
dbSNP Gene:1286 COL4A4
ENSEMBL:ENSG00000081052 COL4A4
ENSEMBL_homo_sapiens_GENE:ENSG00000081052.14 COL4A4
HGNC:2206 COL4A4
KEGG Gene (Homo sapiens):1286 COL4A4
Monarch:1286 COL4A4
NCBI Gene:1286 COL4A4
OMIM:120131 COL4A4
UCSC:P53420 COL4A4
Reference Transcript
RefSeq:NM_000092.4 COL4A4
RefSeq:XM_005246281.3 COL4A4
Other Identifiers
11725265_at
11725266_at
1286
16909172
214602_PM_at
214602_at
229779_PM_at
229779_at
2602116
2602117
2602118
2602119
2602120
2602121
2602122
2602123
2602125
2602131
2602132
2602134
2602138
2602141
2602142
2602143
2602144
2602145
2602146
2602150
2602151
2602152
2602153
2602154
2602155
2602156
2602157
2602158
2602159
2602160
2602161
2602163
2602164
2602165
2602166
2602169
2602170
2602171
2602172
2602173
2602174
2602175
2602176
2602177
2602178
2602179
2602180
2602181
2602182
2602184
2602185
2602186
2602187
2602188
2602191
2602192
2602193
2602194
2602198
2602199
2602200
2602201
2602202
2602209
2602212
2602216
2602217
2602219
35493_at
8059477
88649_at
A_23_P254522
A_33_P3227400
D17391_at
GE87916
GO:0005198
GO:0005201
GO:0005576
GO:0005581
GO:0005587
GO:0005604
GO:0005615
GO:0005783
GO:0005788
GO:0030020
GO:0030198
GO:0030312
GO:0031012
GO:0032836
GO:0043226
GO:0048856
GO:0060090
GO:0062023
HMNXSV003000568
HMNXSV003033888
HMNXSV003056969
Hs.119471.0.A1_3p_at
Hs.180828.0.S2_3p_at
ILMN_1778308
PH_hs_0023458
TC02002832.hg
TC02004836.hg
Participates
as a member of
Collagen alpha-4(IV) chains [extracellular region] (Homo sapiens)
Other forms of this molecule
3x4Hyp-GlcGalHyl-COL4A4 [endoplasmic reticulum lumen]
GlcGalHyl-COL4A4 [endoplasmic reticulum lumen]
3x4Hyp-GalHyl-COL4A4 [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-GalHyl-COL4A4 [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-GlcGalHyl-COL4A4 [endoplasmic reticulum lumen]
GalHyl-COL4A4 [endoplasmic reticulum lumen]
COL4A4 [endoplasmic reticulum lumen]
3x4Hyp-COL4A4 [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-COL4A4 [endoplasmic reticulum lumen]
3x4Hyp-5Hyl-COL4A4 [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-5Hyl-COL4A4 [endoplasmic reticulum lumen]
5Hyl-COL4A4 [endoplasmic reticulum lumen]
5-sulfiliminyl collagen alpha-4(IV) chain [extracellular region]
3,4-Hyp 5-sulfiliminyl collagen alpha-4(IV) chain [extracellular region]
4-Hyp 5-sulfiliminyl collagen alpha-4(IV) chain [extracellular region]
3x4Hyp-COL4A4(39-?) [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL4A4(39-?) [extracellular region]
3x4Hyp-GalHyl-COL4A4(39-?) [extracellular region]
3x4Hyp-5Hyl-COL4A4(?-1690) [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL4A4(?-1690) [extracellular region]
3x4Hyp-3Hyp-COL4A4(39-?) [extracellular region]
GalHyl-COL4A4(39-?) [extracellular region]
GlcGalHyl-COL4A4(?-1690) [extracellular region]
COL4A4(39-?) [extracellular region]
3x4Hyp-GalHyl-COL4A4(?-1690) [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL4A4(?-1690) [extracellular region]
5Hyl-COL4A4(39-?) [extracellular region]
COL4A4(?-1690) [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL4A4(?-1690) [extracellular region]
5Hyl-COL4A4(?-1690) [extracellular region]
GlcGalHyl-COL4A4(39-?) [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL4A4(39-?) [extracellular region]
3x4Hyp-5Hyl-COL4A4(39-?) [extracellular region]
3x4Hyp-COL4A4(?-1690) [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL4A4(39-?) [extracellular region]
3x4Hyp-GlcGalHyl-COL4A4(39-?) [extracellular region]
3x4Hyp-3Hyp-COL4A4(?-1690) [extracellular region]
GalHyl-COL4A4(?-1690) [extracellular region]
3x4Hyp-5Hyl-COL4A4 [extracellular region]
COL4A4 [extracellular region]
GalHyl-COL4A4 [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL4A4 [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL4A4 [extracellular region]
3x4Hyp-COL4A4 [extracellular region]
5Hyl-COL4A4 [extracellular region]
3x4Hyp-GalHyl-COL4A4 [extracellular region]
COL4A4(39-?) [extracellular region]
3,4-Hyp Glu-Gal-Hyl collagen alpha-4(IV) NC1 domain [extracellular region]
4-Hyp 5-Gal-Hyl collagen alpha-4(IV) NC1 domain [extracellular region]
5-Gal-Hyl collagen alpha-4(IV) NC1 domain [extracellular region]
3,4-hydroxyprolyl collagen alpha-4(IV) NC1 domain [extracellular region]
Glu-Gal-Hyl-collagen alpha-4(IV) NC1 domain [extracellular region]
5-hydroxylysyl collagen alpha-4(IV) NC1 domain [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL4A4 NC1 domain [extracellular region]
4-Hyp 5-Hyl collagen alpha-4(IV) NC1 domain [extracellular region]
3,4-Hyp 5-Hyl collagen alpha-4(IV) NC1 domain [extracellular region]
4-hydroxyprolyl collagen alpha-4(IV) NC1 domain [extracellular region]
Collagen alpha-4(IV) NC1 domain [extracellular region]
3x4Hyp-3Hyp-COL4A4 [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL4A4 [extracellular region]
Inferred To
Col4a4 [extracellular region]
(Mus musculus)
Col4a4 [extracellular region]
(Rattus norvegicus)
COL4A4 [extracellular region]
(Canis familiaris)
COL4A4 [extracellular region]
(Sus scrofa)
Modified Residues
Name
O5-glucosylgalactosyl-L-hydroxylysine at unknown position
PsiMod Name
O5-glucosylgalactosyl-L-hydroxylysine
PsiMod Definition
A protein modification that effectively converts an L-lysine residue to O5-glucosylgalactosyl-L-hydroxylysine.
Cross References
RefSeq
NP_000083.3
,
XP_005246338.1
OpenTargets
ENSG00000081052
HPA
ENSG00000081052-COL4A4
GeneCards
P53420
Ensembl
ENSP00000379866
,
ENSG00000081052
,
ENST00000396625
PRO
P53420
Pharos - Targets
P53420
Orphanet
15773
PDB
6WKU
,
5NB1
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