Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2

Stable Identifier
R-HSA-211957
Type
Pathway
Species
Homo sapiens
Compartment
endoplasmic reticulum membrane, endoplasmic reticulum lumen
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2
Click the image above or here to open this pathway in the Pathway Browser

CYP1A2 oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. It is most active in catalyzing N-hydroxylation or N-dealkylation reactions.

Participants
Events
Participates
as an event of
Event Information
Go Biological Process
xenobiotic metabolic process (0006805)
Orthologous Events
Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 (Bos taurus)
Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 (Danio rerio)
Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 (Gallus gallus)
Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 (Mus musculus)
Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 (Rattus norvegicus)
Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 (Sus scrofa)
Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 (Xenopus tropicalis)
Cross References
BioModels Database
Authored
Jassal, B  (2008-05-19)
Reviewed
D'Eustachio, P  (2008-05-28)
Created
Jassal, B  (2008-02-08)
Cite Us!