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MAFA [nucleoplasm]
Stable Identifier
R-HSA-211283
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
MafA
Icon
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Regulation of beta-cell development (Homo sapiens)
Regulation of gene expression in beta cells (Homo sapiens)
FOXOA2-, MAFA-, and PAX6-dependent synthesis of PDX1 protein (Homo sapiens)
MAFA [nucleoplasm] (Homo sapiens)
MAFA-, NKX2-2-, PAX6-, and PDX1-dependent synthesis of insulin precursor protein (Homo sapiens)
MAFA [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8NHW3 MAFA
Gene Names
MAFA
Chain
chain:1-353
Reference Genes
BioGPS Gene:389692 MAFA
COSMIC (genes):MAFA MAFA
CTD Gene:389692 MAFA
dbSNP Gene:389692 MAFA
ENSEMBL:ENSG00000182759 MAFA
HGNC:23145 MAFA
KEGG:hsa:389692 MAFA
Monarch:389692 MAFA
NCBI Gene:389692 MAFA
OMIM:610303 MAFA
UCSC:Q8NHW3 MAFA
Reference Transcript
RefSeq:NM_201589.3 MAFA
Other Identifiers
11758703_s_at
11759465_s_at
17082083
3157446
3157451
3157452
3157453
3157454
3157455
3157456
3157457
3157459
389692
8153409
88684_at
A_24_P127719
GE789420
GO:0000785
GO:0000978
GO:0000981
GO:0001228
GO:0003677
GO:0003700
GO:0005634
GO:0006355
GO:0006357
GO:0009749
GO:0030073
GO:0043226
GO:0045893
GO:0045944
GO:0140110
GO:1990837
HMNXSV003041662
ILMN_1661577
PH_hs_0032487
TC08001715.hg
TC08001716.hg
This entity regulates
Positively
MAFA-, NKX2-2-, PAX6-, and PDX1-dependent synthesis of insulin precursor protein
(Homo sapiens)
FOXOA2-, MAFA-, and PAX6-dependent synthesis of PDX1 protein
(Homo sapiens)
Cross References
RefSeq
NP_963883.2
ENSEMBL
ENSP00000328364
,
ENST00000333480
OpenTargets
ENSG00000182759
HPA
ENSG00000182759-MAFA
PRO
Q8NHW3
Pharos - Targets
Q8NHW3
PDB
4EOT
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