Reactome | DFFB [cytosol]

DFFB [cytosol]

Stable Identifier

R-HSA-211211

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

DFF40/DFFB/CAD

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:O76075 DFFB

Gene Names

DFFB, CAD, DFF2, DFF40

Chain

chain:1-338

Reference Genes

COSMIC (genes):CAD DFFB

COSMIC (genes):DFFB DFFB

ENSEMBL:ENSG00000169598 DFFB

HGNC:2773 DFFB

UCSC:O76075 DFFB

Other Identifiers

11731383_a_at

11731384_x_at

11745428_a_at

11745693_a_at

11745694_x_at

11753611_a_at

11753612_x_at

16658231

1677

206752_PM_s_at

206752_s_at

2317419

2317420

2317514

2317515

2317516

2317517

2317518

2317519

2317520

2317521

2317522

2317523

2317524

2317527

2317528

2317529

2317530

2317531

2317532

2317533

2317537

2317538

2317539

2317540

2317541

2317542

2317546

3203170

34937_at

7897210

A_14_P201751

A_23_P44546

A_24_P278684

A_24_P370626

A_33_P3277012

GE54583

GO:0000785

GO:0003677

GO:0003824

GO:0004518

GO:0004520

GO:0004536

GO:0005515

GO:0005634

GO:0005654

GO:0005730

GO:0005737

GO:0005829

GO:0006308

GO:0006309

GO:0006915

GO:0012501

GO:0016787

GO:0019899

GO:0019904

GO:0030263

GO:0032991

GO:0042802

GO:0043226

GO:0097718

GO:0140097

GO:1902511

HMNXSV003004507

ILMN_1678962

ILMN_2384133

PH_hs_0031751

TC01000074.hg

g4758149_3p_s_at

Participates

as an input of

Association of DFF40 with DFF45 (Homo sapiens)

as a component of

DFFA:DFFB [cytosol] (Homo sapiens)

Other forms of this molecule

DFFB [nucleoplasm]

Inferred To

dffb [cytosol] (Danio rerio)

dffb [cytosol] (Xenopus tropicalis)

Drep4 [cytosol] (Drosophila melanogaster)

DFFB [cytosol] (Bos taurus)

DFFB [cytosol] (Canis familiaris)

DFFB [cytosol] (Sus scrofa)

Dffb [cytosol] (Mus musculus)

Dffb [cytosol] (Rattus norvegicus)

CAD [cytosol] (Gallus gallus)

Cross References

ENSEMBL

ENST00000378209, ENST00000491998, ENSP00000343218, ENSP00000367454, ENSP00000436775, ENST00000339350

OpenTargets

ENSG00000169598

HPA

ENSG00000169598-DFFB

PRO

O76075

Pharos - Targets

O76075

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O00273 DFFA	6	DFFA [cytosol] (R-HSA-211221) DFFA(1-?) [nucleoplasm] (R-HSA-211228) DFFA(225-331) [nucleoplasm] (R-HSA-211188) DFFA(118-224) [nucleoplasm] (R-HSA-211205) DFFA(118-331) [nucleoplasm] (R-HSA-211199) DFFA(1-117) [nucleoplasm] (R-HSA-211185)	0.909	10
UniProt:P61326 MAGOH	1	MAGOH [nucleoplasm] (R-HSA-156658)	0.527	2
UniProt:P0CG47 UBB	20	UBB(77-152) [endocytic vesicle membrane] (R-HSA-939253) UBB(1-76) [endocytic vesicle membrane] (R-HSA-939231) UBB(153-228) [endocytic vesicle membrane] (R-HSA-939171) Ub-33-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783023) Ub-109-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783008) Ub-185-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783046) Ub-215-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783002) Ub-63-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783148) Ub-139-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783012) Ub-158-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783162) Ub-6-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783014) Ub-82-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783015) Ub-163-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783025) Ub-87-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6782998) Ub-11-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783109) Ub-124-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783131) Ub-200-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783100) Ub-48-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783165) Ub-181-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783160) Ub-29-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783070)	0.527	2
UniProt:Q16513 PKN2	2	PKN2 [cytosol] (R-HSA-5623612) p-T816-PKN2 [cytosol] (R-HSA-5623652)	0.527	2

Cite Us!