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CYP2J2 [endoplasmic reticulum membrane]
Stable Identifier
R-HSA-211022
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum membrane
Synonyms
Cytochrome P450 2J2, CPJ2_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Biological oxidations (Homo sapiens)
Phase I - Functionalization of compounds (Homo sapiens)
Cytochrome P450 - arranged by substrate type (Homo sapiens)
Fatty acids (Homo sapiens)
CYP2J2 oxidises ARA (Homo sapiens)
Cytochrome P450 (CYP2J2 based) [endoplasmic reticulum membrane] (Homo sapiens)
CYP2J2 [endoplasmic reticulum membrane] (Homo sapiens)
Xenobiotics (Homo sapiens)
CYP2D6 4-hydroxylates debrisoquine (Homo sapiens)
Cytochrome P450 (CYP2D6 based) [endoplasmic reticulum membrane] (Homo sapiens)
CYP2J2 [endoplasmic reticulum membrane] (Homo sapiens)
CYP2F1 dehydrogenates 3-methylindole (Homo sapiens)
Cytochrome P450 (CYP2F1 based) [endoplasmic reticulum membrane] (Homo sapiens)
CYP2J2 [endoplasmic reticulum membrane] (Homo sapiens)
Coumarin is 7-hydroxylated by CYP2A13 (Homo sapiens)
Cytochrome P450 (CYP2A13 based) [endoplasmic reticulum membrane] (Homo sapiens)
CYP2J2 [endoplasmic reticulum membrane] (Homo sapiens)
Cyclophosphamide is 4-hydroxylated by CYP2B6 (Homo sapiens)
Cytochrome P450 (CYP2B6 based) [endoplasmic reticulum membrane] (Homo sapiens)
CYP2J2 [endoplasmic reticulum membrane] (Homo sapiens)
O-atom dealkylation of dextromethorphan (Homo sapiens)
Cytochrome P450 (CYP2D6 based) [endoplasmic reticulum membrane] (Homo sapiens)
CYP2J2 [endoplasmic reticulum membrane] (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Fatty acid metabolism (Homo sapiens)
Arachidonic acid metabolism (Homo sapiens)
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) (Homo sapiens)
Arachidonic acid is epoxidated to 5,6-EET by CYP(4) (Homo sapiens)
CYP(4) [endoplasmic reticulum membrane] (Homo sapiens)
CYP2J2 [endoplasmic reticulum membrane] (Homo sapiens)
Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) (Homo sapiens)
CYP(5) [endoplasmic reticulum membrane] (Homo sapiens)
CYP2J2 [endoplasmic reticulum membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P51589 CYP2J2
Gene Names
CYP2J2
Chain
chain:1-502
Reference Genes
BioGPS Gene:1573 CYP2J2
COSMIC (genes):CYP2J2 CYP2J2
CTD Gene:1573 CYP2J2
dbSNP Gene:1573 CYP2J2
ENSEMBL:ENSG00000134716 CYP2J2
ENSEMBL_homo_sapiens_GENE:ENSG00000134716.11 CYP2J2
HGNC:2634 CYP2J2
KEGG Gene (Homo sapiens):1573 CYP2J2
Monarch:1573 CYP2J2
NCBI Gene:1573 CYP2J2
OMIM:601258 CYP2J2
UCSC:P51589 CYP2J2
Reference Transcript
RefSeq:NM_000775.3 CYP2J2
Other Identifiers
11722614_a_at
1573
16687914
205073_PM_at
205073_at
2415269
2415270
2415272
2415274
2415275
2415276
2415277
2415278
2415279
2415282
2415291
2415292
500_at
501_g_at
7916616
A_23_P103486
GE62534
GO:0003013
GO:0003824
GO:0004497
GO:0005506
GO:0005576
GO:0005615
GO:0005737
GO:0005783
GO:0005789
GO:0006082
GO:0006629
GO:0006631
GO:0006690
GO:0006805
GO:0008016
GO:0008392
GO:0008404
GO:0008405
GO:0016020
GO:0016491
GO:0016705
GO:0016712
GO:0016853
GO:0019369
GO:0019373
GO:0020037
GO:0043226
GO:0043231
GO:0043651
GO:0046872
GO:0070062
GO:0071614
GO:0106255
GO:0106301
HMNXSV003017935
ILMN_1758731
PH_hs_0009155
TC01002717.hg
U37143_at
g4503226_3p_at
Participates
as a member of
CYP(5) [endoplasmic reticulum membrane] (Homo sapiens)
CYP(4) [endoplasmic reticulum membrane] (Homo sapiens)
Cytochrome P450 (CYP2J2 based) [endoplasmic reticulum membrane] (Homo sapiens)
as a candidate of
Cytochrome P450 (CYP2B6 based) [endoplasmic reticulum membrane] (Homo sapiens)
Cytochrome P450 (CYP2A13 based) [endoplasmic reticulum membrane] (Homo sapiens)
Cytochrome P450 (CYP2D6 based) [endoplasmic reticulum membrane] (Homo sapiens)
Cytochrome P450 (CYP2F1 based) [endoplasmic reticulum membrane] (Homo sapiens)
Inferred To
cyp2x8 [endoplasmic reticulum membrane]
(Danio rerio)
cyp2x9 [endoplasmic reticulum membrane]
(Danio rerio)
cyp-33d1 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
cyp-33d3 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
cyp2aa12 [endoplasmic reticulum membrane]
(Danio rerio)
cyp2ae1 [endoplasmic reticulum membrane]
(Danio rerio)
cyp2n13 [endoplasmic reticulum membrane]
(Danio rerio)
LOC105945483 [endoplasmic reticulum membrane]
(Xenopus tropicalis)
cyp-35a2 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
cyp-35a1 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
CYP2J2 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
CYP2J2 [endoplasmic reticulum membrane]
(Canis familiaris)
CYP2J2 [endoplasmic reticulum membrane]
(Dictyostelium discoideum)
CYP2J2 [endoplasmic reticulum membrane]
(Drosophila melanogaster)
CYP2J2 [endoplasmic reticulum membrane]
(Gallus gallus)
CYP2J2 [endoplasmic reticulum membrane]
(Mus musculus)
CYP2J2 [endoplasmic reticulum membrane]
(Rattus norvegicus)
cyp-35a5 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
cyp-35a3 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
cyp-35a4 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
cyp-33c1 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
cyp2aa2 [endoplasmic reticulum membrane]
(Danio rerio)
Homologues of CYP2J2 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
Homologues of CYP2J2 [endoplasmic reticulum membrane]
(Danio rerio)
Homologues of CYP2J2 [endoplasmic reticulum membrane]
(Dictyostelium discoideum)
Homologues of CYP2J2 [endoplasmic reticulum membrane]
(Drosophila melanogaster)
Homologues of CYP2J2 [endoplasmic reticulum membrane]
(Rattus norvegicus)
zgc:110749 [endoplasmic reticulum membrane]
(Danio rerio)
cyp-33c5 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
cyp-33c12 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
cyp-33c3 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
cyp2ad3 [endoplasmic reticulum membrane]
(Danio rerio)
cyp-33c7 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
cyp-33c9 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
cyp-33e2 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
cyp-34a1 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
cyp-33b1 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
CYP2J34 [endoplasmic reticulum membrane]
(Sus scrofa)
cyp-34a9 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
cyp-35b2 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
cyp-34a5 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
Cyp2j16 [endoplasmic reticulum membrane]
(Rattus norvegicus)
cyp-34a7 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
cyp2x10.1 [endoplasmic reticulum membrane]
(Danio rerio)
LOC530929 [endoplasmic reticulum membrane]
(Bos taurus)
cyp2p8 [endoplasmic reticulum membrane]
(Danio rerio)
dach-1 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
cyp2p7 [endoplasmic reticulum membrane]
(Danio rerio)
cyp-34a10 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
zgc:162502 [endoplasmic reticulum membrane]
(Danio rerio)
cyp-33a1 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
cyp2p10 [endoplasmic reticulum membrane]
(Danio rerio)
daf-9 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
cyp2aa9 [endoplasmic reticulum membrane]
(Danio rerio)
cyp2v1 [endoplasmic reticulum membrane]
(Danio rerio)
cyp-35c1 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
cyp-33c2 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
cyp-33c6 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
cyp-33c11 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
cyp-33c4 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
cyp2aa3 [endoplasmic reticulum membrane]
(Danio rerio)
cyp2ad2 [endoplasmic reticulum membrane]
(Danio rerio)
cyp-33c8 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
cyp2ad6 [endoplasmic reticulum membrane]
(Danio rerio)
cyp-33e1 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
cyp-33e3 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
cyp-34a2 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
cyp-35b1 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
cyp-34a8 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
cyp-35b3 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
cyp-34a6 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
si:dkey-286h2.3 [endoplasmic reticulum membrane]
(Danio rerio)
cyp-23a1 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
cyp2j22 [endoplasmic reticulum membrane]
(Danio rerio)
cyp2p6 [endoplasmic reticulum membrane]
(Danio rerio)
Cross References
RefSeq
NP_000766.2
ZINC - World Drugs
CP2J2_HUMAN
Guide to Pharmacology - Targets
1332
OpenTargets
ENSG00000134716
ZINC - FDA approved
CP2J2_HUMAN
ZINC - Substances
CP2J2_HUMAN
ZINC - Biogenic
CP2J2_HUMAN
ZINC target
P51589
PRO
P51589
ZINC - Investigational
CP2J2_HUMAN
ZINC - Metabolites
CP2J2_HUMAN
IntEnz
1.14.14.73
,
5.4.4.7
,
1.14.14.74
GeneCards
P51589
HPA
ENSG00000134716-CYP2J2
Ensembl
ENSG00000134716
,
ENST00000371204
,
ENSP00000360247
Pharos - Targets
P51589
ZINC - Predictions - Purchasable
CP2J2_HUMAN
Orphanet
24453
HMDB Protein
HMDBP01565
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