NEUROG3-dependent synthesis of NEUROD1

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Reaction [omitted]
Homo sapiens
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The NEUROD1 gene is transcribed, its mRNA is translated, and the protein product is transported to the nucleus. NEUROD1 transcription requires the activity of the NEUROG3 transcription factor (Heremans et al. 2002; Mellitzer et al. 2006).

Literature References
PubMed ID Title Journal Year
12403815 Recapitulation of embryonic neuroendocrine differentiation in adult human pancreatic duct cells expressing neurogenin 3

Heremans, Y, Van De Casteele, M, in't Veld, P, Gradwohl, G, Serup, P, Madsen, OD, Pipeleers, D, Heimberg, H

J Cell Biol 2002
16511571 IA1 is NGN3-dependent and essential for differentiation of the endocrine pancreas

Mellitzer, G, Bonne, S, Luco, RF, Van De Casteele, M, Lenne-Samuel, N, Collombat, P, Mansouri, A, Lee, J, Lan, M, Pipeleers, D, Nielsen, FC, Ferrer, J, Gradwohl, G, Heimberg, H

EMBO J 2006
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