Reactome | NEUROG3-dependent synthesis of NEUROD1

NEUROG3-dependent synthesis of NEUROD1

Stable Identifier

R-HSA-210920

Type

Reaction [omitted]

Species

Homo sapiens

Compartment

nucleoplasm

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The NEUROD1 gene is transcribed, its mRNA is translated, and the protein product is transported to the nucleus. NEUROD1 transcription requires the activity of the NEUROG3 transcription factor (Heremans et al. 2002; Mellitzer et al. 2006).

Literature References

PubMed ID	Title	Journal	Year
12403815	Recapitulation of embryonic neuroendocrine differentiation in adult human pancreatic duct cells expressing neurogenin 3 Heremans, Y, Van De Casteele, M, in't Veld, P, Gradwohl, G, Serup, P, Madsen, OD, Pipeleers, D, Heimberg, H	J Cell Biol	2002
16511571	IA1 is NGN3-dependent and essential for differentiation of the endocrine pancreas Mellitzer, G, Bonne, S, Luco, RF, Van De Casteele, M, Lenne-Samuel, N, Collombat, P, Mansouri, A, Lee, J, Lan, M, Pipeleers, D, Nielsen, FC, Ferrer, J, Gradwohl, G, Heimberg, H	EMBO J	2006