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HNF1B-dependent synthesis of HNF6 protein
Stable Identifier
R-HSA-210784
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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Developmental Biology (Homo sapiens)
Regulation of beta-cell development (Homo sapiens)
Regulation of gene expression in early pancreatic precursor cells (Homo sapiens)
HNF1B-dependent synthesis of HNF6 protein (Homo sapiens)
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The HNF6 gene is transcribed, its mRNA is translated, and the protein product is transported to the nucleus. HNF6 transcription requires the activity of the HNF1B transcription factor. These events and interactions have not been studied directly in humans, but are inferred from corresponding ones worked out in the mouse.
Participants
Input
ONECUT1 gene [nucleoplasm]
(Homo sapiens)
Output
ONECUT1 [nucleoplasm]
(Homo sapiens)
Participates
as an event of
Regulation of gene expression in early pancreatic precursor cells (Homo sapiens)
This event is regulated
Positively by
Regulator
HNF1B [nucleoplasm]
(Homo sapiens)
Inferred From
HNF1b transactivates Hnf6 (Mus musculus)
Authored
Tello-Ruiz, MK (2008-05-24)
Ferrer, J (2008-05-24)
Reviewed
Jensen, J (2008-05-13)
Created
D'Eustachio, P (2008-01-16)
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