PTPN1 [cytosol]

Stable Identifier
R-HSA-210625
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
PTP1B, Protein-tyrosine phosphatase 1B
Locations in the PathwayBrowser for interactor UniProt:P56945 BCAR1
External Reference Information
External Reference
Gene Names
PTPN1, PTP1B
Chain
chain:1-435
Other Identifiers
0000730348
11717146_at
11717147_a_at
16914844
16914859
202716_at
3888722
3888723
3888724
3888725
3888747
3888751
3888753
3888755
3888761
3888762
3888764
3888766
3888767
3888769
3888770
3888772
3888773
3888774
3888775
3888776
3888777
3888778
3888783
3888785
40137_at
5770
588_at
591_s_at
8063394
A_14_P115470
A_23_P338890
GE57927
GO:0002376
GO:0003674
GO:0003723
GO:0004721
GO:0004725
GO:0005158
GO:0005515
GO:0005575
GO:0005622
GO:0005737
GO:0005739
GO:0005759
GO:0005768
GO:0005769
GO:0005783
GO:0005789
GO:0005829
GO:0005886
GO:0006464
GO:0006470
GO:0006810
GO:0006950
GO:0007010
GO:0007165
GO:0007257
GO:0008150
GO:0008219
GO:0008270
GO:0008286
GO:0009056
GO:0009966
GO:0009968
GO:0015031
GO:0016020
GO:0016021
GO:0016192
GO:0016311
GO:0016787
GO:0016791
GO:0019899
GO:0019901
GO:0030061
GO:0030100
GO:0030948
GO:0030968
GO:0030971
GO:0031410
GO:0031532
GO:0032991
GO:0033157
GO:0034620
GO:0034976
GO:0035335
GO:0035791
GO:0036498
GO:0043167
GO:0043226
GO:0043407
GO:0045296
GO:0046626
GO:0046627
GO:0046875
GO:0051721
GO:0060338
GO:0060397
GO:0061098
GO:0070373
GO:0097443
GO:0098554
GO:1902202
GO:1902236
GO:1903896
GO:1903898
GO:1990264
GO:2000646
ILMN_1681591
ILMN_3310291
M31724_at
M33684_s_at
PH_hs_0025079
TC20000403.hg
TC20000405.hg
g4506288_3p_at
Participant Of
Inferred To
Cross References
ZINC - World Drugs
OpenTargets
ZINC - FDA approved
ZINC - Substances
ZINC target
ZINC - Biogenic
PRO
PDB
1OEV, 5QG0, 5QG8, 1I57, 5KA7, 5QFA, 5K9W, 5QF5, 1LQF, 5QEK, 2CMC, 5KAD, 2CMA, 2HNQ, 1PTT, 5QFD, 5QFL, 1OES, 5QG3, 3ZV2, 1A5Y, 6PHS, 2ZN7, 1PYN, 6PM8, 6OLQ, 5QDN, 1BZH, 2CNG, 6B8E, 5QFS, 2VEW, 5QEN, 5QFV, 2H4G, 5QF0, 4QAH, 2QBR, 1T48, 3D9C, 5QDR, 5QDZ, 2F6F, 1C88, 5QEI, 3QKP, 1KAV, 1C83, 5QFJ, 1Q6J, 5QDK, 5QGE, 5QEL, 6B8Z, 1NL9, 5QEC, 1T49, 6CWV, 5KA3, 1NWL, 5QDO, 6NTP, 2VEX, 1C86, 5QEG, 1GFY, 5QEX, 2VEU, 3A5K, 5QF8, 5KA0, 1Q6T, 1Q6N, 2BGE, 5QDH, 2AZR, 5QE2, 5QFG, 2QBP, 5QF3, 2FJN, 1BZC, 1PTV, 5QET, 1ECV, 5KA4, 5QF4, 2CNH, 5K9V, 2F6V, 5QEW, 5QG2, 5QFK, 5QFC, 5QF7, 5QE6, 3EAX, 2CNF, 1G7G, 4ZRT, 2QBQ, 2NT7, 5QDQ, 5QFU, 5QFX, 1T4J, 5KA9, 1ONY, 5QFP, 1OEU, 6B95, 5QE4, 5QFI, 2CNI, 1KAK, 5KAC, 6CWU, 5KA2, 3ZMP, 2ZMM, 5QFN, 5QEF, 4BJO, 5QDE, 4QBW, 1G1G, 5QEQ, 5QGB, 5QDY, 1Q6S, 6PG0, 3SME, 2F6Z, 2BGD, 5QE1, 5QEH, 1Q1M, 1NO6, 5QF2, 2HB1, 5QDT, 1AAX, 5QFZ, 5QEB, 2FJM, 3EU0, 1PXH, 1QXK, 2F6T, 5QDM, 1EEO, 2B4S, 5QFR, 2H4K, 1WAX, 4QAP, 5QEE, 3CWE, 2QBS, 5QE5, 1PA1, 5QDG, 5QF6, 1PTU, 5QEZ, 2CM8, 1BZJ, 1C84, 5QFO, 2F71, 5QG7, 6PHA, 1PTY, 5KA8, 5QDJ, 3A5J, 5QES, 2F6W, 1OEO, 5QFW, 5QE3, 2CM3, 5QDV, 6PFW, 1C85, 5QEV, 5T19, 6OMY, 6BAI, 5QFF, 5QFM, 5QG5, 1NWE, 1G1F, 2B07, 5QEP, 5QE9, 5QGA, 2F6Y, 3I80, 6B8X, 1PH0, 5QDS, 4QBE, 5QGD, 1NZ7, 5QFB, 5QFQ, 1L8G, 5QEA, 4I8N, 5QG1, 5QG9, 5QDL, 1EEN, 5QFY, 5QFT, 5QED, 1OET, 1G7F, 5QDF, 5QDW, 5QEO, 2CMB, 5KAA, 6PGT, 5QE7, 5QE0, 5QEY, 1SUG, 2CNE, 5QF1, 1NNY, 5QG6, 3QKQ, 5QDI, 5QEJ, 1OEM, 2CM7, 1Q6M, 1C87, 4Y14, 5QEU, 5QDU, 5QEM, 2CM2, 5QGF, 3EB1, 2NTA, 3ZMQ, 2VEY, 1G1H, 5KAB, 5QDP, 2HNP, 5QDX, 6OLV, 5QG4, 6B8T, 5QFE, 5KA1, 5QF9, 3I7Z, 5QE8, 1ONZ, 2VEV, 5QFH, 2F70, 1JF7, 5QGC, 5QER, 6B90, 1XBO, 1Q6P
ZINC - Investigational
ZINC - Metabolites
GeneCards
ZINC - Predictions - Purchasable
HMDB Protein
Interactors (39)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P06213 INSR  6 0.979 32
 UniProt:P12931 SRC  6 0.937 14
 UniProt:P00533 EGFR  59 0.864 8
 UniProt:O60674 JAK2  8 0.819 5
 UniProt:P56945 BCAR1  4 0.786 5
 UniProt:Q61140 Bcar1  6 0.756 5
 UniProt:Q9H1D0 TRPV6  1 0.744 6
 UniProt:P08581 MET  7 0.713 3
 UniProt:P09619 PDGFRB  3 0.713 3
 UniProt:P08069 IGF1R  3 0.702 3
 UniProt:Q03135 CAV1  5 0.697 5
 UniProt:P07384 CAPN1  4 0.676 4
 UniProt:P05622  3 0.656 3
 UniProt:Q96TC7 RMD3      0.646 4
 UniProt:P10912 GHR  7 0.645 5
 UniProt:P62993 GRB2  1 0.642 4
 UniProt:P40763 STAT3  10 0.623 2
 ChEBI:17440 4-NITROPHENYL DIHYDROGEN PHOSPHATE      0.623 2
 UniProt:P11274-1 BCR      0.602 3
 UniProt:P19235 EPOR  2 0.602 3
 UniProt:Q63767  4 0.591 5
 UniProt:O43561 LAT  3 0.591 3
 UniProt:Q63768 Crk  2 0.589 2
 UniProt:P62994 Grb2  3 0.589 3
 UniProt:Q9WUD9 Src  11 0.564 2
 UniProt:P42229 STAT5A  5 0.558 2
 IntAct:EBI-22326698 CCSB ORF ID      0.556 3
 UniProt:P10686 Plcg1  8 0.556 4
 UniProt:Q9NPL8 TIMMDC1  1 0.556 3
 UniProt:Q8N661 TMEM86B  1 0.556 3
 UniProt:Q96HV5 TM41A      0.556 3
 UniProt:Q9GZR5 ELOVL4  1 0.556 3
 UniProt:Q13520 AQP6  1 0.556 3
 UniProt:P57054 PIGP  1 0.556 3
 UniProt:Q96GX1 TCTN2  1 0.527 3
 UniProt:P35570 Irs1  7 0.525 3
 UniProt:P15116  3 0.524 3
 UniProt:P02730 SLC4A1  8 0.499 2
 UniProt:P05106 ITGB3  3 0.499 4
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