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SLC1A6 [plasma membrane]
Stable Identifier
R-HSA-210433
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
EAAT4
Locations in the PathwayBrowser
Expand all
Neuronal System (Homo sapiens)
Transmission across Chemical Synapses (Homo sapiens)
Neurotransmitter release cycle (Homo sapiens)
Glutamate Neurotransmitter Release Cycle (Homo sapiens)
SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ (Homo sapiens)
SLC1A1-3,6,7 [plasma membrane] (Homo sapiens)
SLC1A6 [plasma membrane] (Homo sapiens)
Transport of small molecules (Homo sapiens)
SLC-mediated transmembrane transport (Homo sapiens)
Transport of inorganic cations/anions and amino acids/oligopeptides (Homo sapiens)
SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol (Homo sapiens)
SLC1A1-3,6,7 [plasma membrane] (Homo sapiens)
SLC1A6 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P48664 SLC1A6
Gene Names
SLC1A6, EAAT4
Chain
chain:1-564
Reference Genes
BioGPS Gene:6511 SLC1A6
COSMIC (genes):SLC1A6 SLC1A6
CTD Gene:6511 SLC1A6
dbSNP Gene:6511 SLC1A6
ENSEMBL:ENSG00000105143 SLC1A6
HGNC:10944 SLC1A6
KEGG:hsa:6511 SLC1A6
Monarch:6511 SLC1A6
NCBI Gene:6511 SLC1A6
OMIM:600637 SLC1A6
UCSC:P48664 SLC1A6
Reference Transcript
RefSeq:NM_001272088.1 SLC1A6
RefSeq:NM_005071.2 SLC1A6
RefSeq:XM_006722842.1 SLC1A6
RefSeq:XM_006722844.1 SLC1A6
RefSeq:XM_017027152.1 SLC1A6
RefSeq:NM_001272087.1 SLC1A6
Other Identifiers
11744870_a_at
11759665_a_at
1554592_PM_a_at
1554592_a_at
1554593_PM_s_at
1554593_s_at
16869725
206882_PM_at
206882_at
35096_at
3853037
3853038
3853039
3853040
3853042
3853043
3853044
3853045
3853046
3853047
3853049
3853050
3853051
3853052
3853053
3853054
3853058
55891_i_at
55893_r_at
6511
8034907
A_24_P179467
GE58976
GO:0001504
GO:0005215
GO:0005313
GO:0005314
GO:0005794
GO:0005856
GO:0005886
GO:0006811
GO:0006836
GO:0006865
GO:0007268
GO:0015175
GO:0015179
GO:0015183
GO:0015293
GO:0015501
GO:0015804
GO:0015810
GO:0015813
GO:0016020
GO:0023052
GO:0042391
GO:0042734
GO:0043226
GO:0045111
GO:0046872
GO:0051649
GO:0055085
GO:0098712
GO:0098796
GO:0098978
GO:0140009
GO:1902475
HMNXSV003040459
HMNXSV003054258
Hs2.113602.2.S1_3p_s_at
ILMN_2171471
PH_hs_0023880
PH_hs_0032730
U18244_at
g4827011_3p_at
Participates
as a member of
SLC1A1-3,6,7 [plasma membrane] (Homo sapiens)
Inferred To
Eaat1 [plasma membrane]
(Drosophila melanogaster)
glt-1 [plasma membrane]
(Caenorhabditis elegans)
glt-5 [plasma membrane]
(Caenorhabditis elegans)
SLC1A6 [plasma membrane]
(Bos taurus)
SLC1A6 [plasma membrane]
(Caenorhabditis elegans)
SLC1A6 [plasma membrane]
(Canis familiaris)
SLC1A6 [plasma membrane]
(Gallus gallus)
SLC1A6 [plasma membrane]
(Mus musculus)
SLC1A6 [plasma membrane]
(Rattus norvegicus)
SLC1A6 [plasma membrane]
(Sus scrofa)
glt-7 [plasma membrane]
(Caenorhabditis elegans)
slc1a6 [plasma membrane]
(Xenopus tropicalis)
Homologues of SLC1A6 [plasma membrane]
(Caenorhabditis elegans)
glt-3 [plasma membrane]
(Caenorhabditis elegans)
glt-6 [plasma membrane]
(Caenorhabditis elegans)
Cross References
RefSeq
NP_005062.1
,
XP_016882641.1
,
XP_006722907.1
,
XP_006722905.1
,
NP_001259017.1
,
NP_001259016.1
Guide to Pharmacology - Targets
871
ENSEMBL
ENST00000221742
,
ENST00000544886
,
ENST00000598504
,
ENSP00000472133
,
ENSP00000471781
,
ENSP00000446175
,
ENSP00000221742
,
ENST00000594383
OpenTargets
ENSG00000105143
HPA
ENSG00000105143-SLC1A6
ZINC - Substances
EAA4_HUMAN
ZINC target
P48664
PRO
P48664
Pharos - Targets
P48664
GlyGen
P48664
ZINC - Predictions - Purchasable
EAA4_HUMAN
HMDB Protein
HMDBP03267
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